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Biomedical subjects

J Faulborn

Publications and source records attributed to J Faulborn.

At least 55 records · Page 3Linked to original sources
PubMed1985

Microproliferations in proliferative diabetic retinopathy and their relationship to the vitreous: corresponding light and electron microscopic studies.

Using a special embedding method, autopsied eyes with proliferative diabetic retinopathy were studied. In areas with no posterior vitreous detachment, small proliferations may arise multifocally and grow within the vitreous cortex. The fibrous material of the vitreous cortex is densely interconnected with and obviously incorporated into the newly formed proliferated tissue, a process which causes coarse traction lines on the vitreous cortex lamellae. The clinical consequences of these findings are discussed.

Adult↗
PubMed1985

[Histologic studies on the effect of light coagulation of the retina on the vitreous body].

Up to 6 months after panretinal photocoagulation of rabbit eyes the subsequent changes in the vitreous body were examined histologically by means of a stereomicroscope. Marked changes were evident: severe exudation into all of the vitreous tissue during the early follow-up period, circumscribed areas of higher density or loss of normal density, membrane-like structures, confluent cavities and liquefaction of most of the tissue at the later postcoagulative stage.

Animals↗
PubMed1984

[Vascular and ocular complications in a child with homocystinuria].

Homocystinuria, only partially responsive to pyridoxine, was first diagnosed at the age of 14 years in a boy with high myopia, spherophakia and subluxated lenses, when surgical removal of a dislocated lens became necessary. 2 years previously a fracture of the left tibia, treated conservatively, had been followed by ischemia of the leg necessitating amputation. Postoperatively, deep vein thrombosis had developed in the right leg. Plasma homocysteine was lowered to undetectable levels by treatment with betaine in addition to pyridoxine, folic acid and reduction of protein intake. During the two years on treatment no further thromboembolic complications have occurred.

Adolescent↗
PubMed1984

[Histology and therapy of diabetic traction detachment].

Diabetic tractional detachment of the retina is caused by shrinking processes of the vitreous, which at most detaches only partially, and by shrinking of epiretinal proliferations. The shrinking of the vitreous results in tractional forces working centripetally and toward the base of the vitreous. The shrinking of the epiretinal proliferations, however, results in a tangential gathering of the retina. The two processes are usually found together in diabetic tractional retinal detachment. Treatment consists of a vitrectomy to eliminate the centripetal forces and tractions to the vitreous base. Further relief and unfolding of the retina is achieved by segmentation of the epiretinal membranes. Additional conventional retinal surgery procedures and implantation of silicone oil may become necessary in especially unfavorable cases. The surgical technique is explained with examples of typical situations.

Adult↗
PubMed1983

[Suitability of resorbable sutures in the treatment of corneal wounds].

In a series of cataract operations with a corneal incision PDS 10-0 absorbable sutures were tested. In contrast to deeper PDS sutures, such as are used in corneoscleral incisions, the corneal sutures opened as early as between 13 and 30 days postoperatively in 5 out of 7 cases. Postoperative irritation was more severe and lasted longer than is usual when non absorbable sutures are used. This was probably caused by ends of the thread which had not yet been absorbed, resulting in a foreign body irritation of long duration. Altogether, absorbable PDS 10-0 sutures are only suitable for corneal wound closure to a limited extent.

Absorption↗
PubMed1983

Combined macroscopic, light microscopic, scanning, and transmission electron microscopic investigation of the vitreous body. 3. The structure of the anterior border layer of the vitreous.

The anterior vitreous border layer consists of multiple net-like densely compacted individual lamellae as shown by combined macroscopic, light microscopic, scanning, and transmission electron microscopic investigations. Each lamella displays a polygonal two-dimensional meshwork formed by vitreous fibrils. This multilamellar border layer is reinforced by zonula fibres which merge with anterior lamellae. Probably this special architecture corresponds to the membrane-like function as mentioned by Balazs.

Adult↗
PubMed1981

[Treatment of bacterial endophthalmitis by vitrectomy and intraocularly administered antibiotics (author's transl)].

Local and systemic applications of antibiotics in cases of vitreous bacterial infections have proved insufficient because of blood-vitreous barriers. Intravitreal antibiotic injections overcome these barriers and may control the infection. Recommendations are given for intravitreal therapy with Gentamicin, combined with a pars plana vitrectomy in advanced infections.

Anti-Bacterial Agents↗
PubMed1980

[Prognosis of vitrectomy].

Of 63 eyes on which vitrectomy was performed with a follow-up of at least six months 34 had an ERG with a b-wave of 50 muV or more preoperatively. Twenty-nine eyes had a b-wave of less than 50 muV. Twenty-six (76%) with an ERG > 50 muV, but only five eyes with an ERG < 50 muV had useful vision postoperatively. Of the eyes with an ERG <50 muV and without useful vision post-operatively, 75% were found intraoperatively to have a total retinal detachment. From these results it is concluded that the preoperative ERG findings are of great value for evaluating the prognosis of a vitrectomy.

Electroretinography↗
PubMed1978

[Reaction of ocular tissues to scleral-implant and encircling material: polyamide--silicone--polyester (author's transl)].

Twenty-two human eyes and one rejected Silastic sponge were examined histopathologically for the reaction of ocular tissues to buckling and encircling materials. The eyes were enucleated 22 days to 14 years following retinal detachment surgery. Silicone implants, Silastic sponges, and Mersilene bands were very well tolerated by the eye, whereas nylon threads caused a moderate and prolonged granulomatous inflammation due to their susceptability to enzymatic decomposition. This reaction, however, does not seem to be of major clinical importance, as the amount of nylon used in detachment operations is low. Atrophy of the underlying sclera can happen with any of the above-mentioned materials and depends mostly on mechanical factors of the implant and on the intraocular pressure. Even with total transcleral erosion of the buckling or encircling material, no severe histopathologic changes could be found in the overlying choroid and retina.

Choroid↗