Mid-line presentation of cervical lymphomata.
Three cases of lymphoma are reported, all of which presented as a mid-line cervical swelling and appeared to be localised disease. The importance of early removal of such lesions is emphasized.
Adult↗
Biomedical subjects
J G Buckley
Publications and source records attributed to J G Buckley.
Kikuchi's disease--apparent malignancy of a neck mass.
We report a case of Kikuchi's disease presenting as cervical lymphadenopathy in an adolescent. The original histological diagnosis in this case was a metastatic neoplasm. We wish to highlight the importance of this rare condition because of its potential for mimicking malignancy.
Adolescent↗
Total laryngotracheal hypoplasia in a case of G syndrome.
We report a case of congenital hypoplasia of the larynx and trachea in the presence of an essentially normal cartilaginous structure. To our knowledge this abnormality is not recognised in the literature. Previously reported hypoplastic laryngeal anomalies have all shown anatomical defects ranging from clefts to atresia (Smith and Bain 1965, Gatti et al., 1987). Similarly total congenital tracheal stenosis is accompanied by abnormalities of the cartilaginous structure, usually complete tracheal rings. These types of anomaly typically present either at, or soon after, birth and are associated with other congenital abnormalities. In this particular case the laryngotracheal hypoplasia occurred in the context of a herditary condition of multiple congenital abnormalities known as G syndrome (also known as Opitz-Frias syndrome or the Opitz-G syndrome).
Abnormalities, Multiple↗
Hypoplastic superficial femoral artery associated with bilateral persistent sciatic arteries: a diagnostic pitfall.
A patient with unsuspected bilateral persistent sciatic arteries (PSAs) underwent angiography following a gunshot wound to the right thigh. A hypoplastic superficial femoral artery associated with this rare vascular anomaly was misdiagnosed as being traumatically occluded. Pitfalls in the diagnosis of PSA as well as the embryology, clinical features, and complications are discussed.
Adult↗
General considerations on distant metastases from head and neck cancer.
Mortality in head and neck cancer is due to locoregional disease, distant metastases or intercurrent disease. As treatment of the primary tumor and cervical metastases has improved, the proportion of deaths from co-morbidity and from distant metastases has increased. Distant metastases almost invariably herald a poor prognosis in head and neck cancer with an average survival of 4.3-7.3 months and treatment is usually palliative. Reliable detection is important to prevent inappropriate treatment. The risk is related to the site, stage and histology of the primary tumor and the presence of cervical metastases. Early detection and treatment of cervical metastases may prevent distant metastases. Accurate staging of tumors helps to identify high-risk tumors that should be specifically investigated for distant metastases.
Head and Neck Neoplasms↗
Screening tests to evaluate distant metastases in head and neck cancer.
Investigation for distant metastases is part of the staging process of a primary tumor or recurrent disease before treatment. The lung is the most frequent site followed by bone and liver. Advanced stage and cervical metastases are the most important predictors of metastases. Almost all distant metastases are associated with lung metastases. Computed tomography scan of the chest is the single most effective investigation. The value of routine screening tests is questionable and merits further investigation.
Bone Neoplasms↗
The treatment of distant metastases in head and neck cancer--present and future.
At the present time the occurrence of distant metastases in patients with head and neck squamous cell carcinoma means that lifespan is measured in months. In most instances treatment is purely palliative. Isolated lung metastasis can be successfully removed with long-term disease control in selected patients. Radiotherapy can be useful for palliation of bone metastases and occasionally lung or brain metastases. Chemotherapy does not have a major impact at the present time except for the treatment of metastases from nasopharyngeal cancer. Palliative symptomatic care, along with appropriate pain control, is essential since pain management is very important in these patients. A significant change in the survival of patients with head and neck cancer is only likely to occur by the development of new approaches to treatment. Blocking tumor angiogenesis and treatment based on genetic abnormalities or cell surface receptors offer the two strategies that are most likely to be successful.
Head and Neck Neoplasms↗
Post-angiographic femoral artery injuries.
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Aneurysm↗