Scanning electron microscopy of gastroscopic biopsies.
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Biomedical subjects
Publications and source records attributed to J Goodwin.
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To assess restoration of pulmonary perfusion after pulmonary embolism serial lung scans were carried out on 74 patients. Of these, one-third showed almost complete recovery, one-third improved, and the remainder either failed to improve or became worse. Perfusion was most rapidly restored in the first few days after the embolus and more slowly during the next two to three weeks.Untreated patients improved less often and had more new defects in perfusion than patients treated with anticoagulant therapy, no difference occurring in either the amount of improvement or in the rate of recovery of perfusion between patients treated with different anticoagulant regimens. There was evidence of further pulmonary emboli in 35% of treated patients, 82% of these occurring within two weeks of the initial embolus. Patients with defects in perfusion greater than 30% showed considerable improvement but recovered less well than those with smaller defects.
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Sense RNA-mediated virus resistance has been described for transgenic plants expressing potyviral capsid protein sequences. This study was undertaken to determine if expression of other viral sequences could induce this type of virus resistance. Plants showing highly resistant or 'recovery' phenotypes were generated by expressing the tobacco etch virus (TEV) 6 kDa/21 kDa reading frames. Expression of translatable or untranslatable versions of this TEV sequence produced resistant lines. Highly resistant and recovery phenotype plants expressing TEV coat protein sequences. High transcription rates with low steady-state levels of the transgene transcript generally correlated with resistance. During recovery and induction of the resistance, RNA and protein steady-state levels decreased 5- to 20-fold, while transcription of the transgene continued at a similar level. A posttranscriptional, cellular system eliminating sequences contained in the transgene transcript and viral genome would be consistent with the results.
A simple movement-analysis system is described which provides a video display of the moving image and an easily-observable EMG signal in the form of a time-synchronized light-emitting-diode (LED) display. Its salient feature is the economic and meaningful way in which both data are displayed simultaneously. Its applications in the field of clinical education and training, in diagnosis, and in rehabilitation are discussed.
This investigation compared the reliability and interchangeable use of three currently available goniometers--a universal goniometer, a fluid goniometer, and an electrogoniometer. Three consecutive readings of the active range of movement of the right elbow joint were taken from each of 23 healthy female volunteers; three experienced observers each used each type of goniometer on two occasions. A balanced experimental design was used to eliminate order effects with respect to subject, tester, or goniometer, and a rigid protocol was employed to reduce error due to diurnal or methodological variations. The results show that there are significant differences between the goniometers used, the testers, and the replications. Significant interaction effects also exist between the goniometers and the occasion, the goniometers and the testers, and the testers and replications. The data suggest that the interchangeable use of different types of goniometer in a clinical setting is inadvisable.
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Several factors make 1980s Wisconsin a useful window on the social changes now shaping the response by psychiatry and other medical specialties to patients who accuse physicians of sexual misconduct. The state medical board disciplined 19 such physicians in the 1980s, in contrast to 1 each in the two prior decades, as the state weathered several highly publicized cases in which multiple complainants accused prominent psychiatrists. Wisconsin was one of the first states to enact criminalization (1984) and mandatory reporting (1988) laws. Also, the relatively high number of physicians (3% of the state's psychiatrists) disciplined in the 1980s allows a beginning look at the epidemiology of this problem. Several patterns emerged: 1) Lone complainants who are psychiatric patients face many pressures. Fewer than 25% of successful cases against psychiatrists involved a lone complainant, while all the nonpsychiatrists were disciplined on the basis of a single patient's complaint. 2) More than half of disciplined psychiatrists had regained licensure by decade's end. Neither multiple sexual complainants nor multiple types of complaints seemed to deter relicensure. However, no physician with a criminal conviction has been relicensed. 3) Surprisingly, several connections were noted among offenders, including mentorships, friendships, and therapy relationships. Three disciplined psychiatrists were past presidents of local psychiatric societies. Psychiatrists who had been disciplined were significantly more likely to have been trained under one of the eminent sexual abusers than were other male psychiatrists in the state.
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