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Biomedical subjects

J Haot

Publications and source records attributed to J Haot.

134 records · Page 8Linked to original sources
PubMedDate not supplied

[Hepatic angiosarcoma developed 5 years following treatment for subacute glomerulonephritis].

A patient with hepatic angiosarcoma is described. This tumour, thought rare, still generates clinical interest, because of its characteristic association with occupational exposure to certain chemicals such as vinyl chloride and thorotrast. That association has led to extensive screening of high risk populations. An additional case of liver angiosarcoma which probably developed following long-term treatment with cyclophosphamide. The significant aspects of this tumour are delineated and the diagnostic modalities are discussed.

Cyclophosphamide↗
PubMedDate not supplied

Primary melanosarcoma of the rectum.

We report two cases of anorectal malignant melanoma observed these last four years in the department. The first case was a 62-year-old female patient, and the second case was a 68-year-old male patient. Both suffered from a primary rectal tumour, arising from the rectum, with an intact anal canal. There were pulmonary metastases in the latter patient. At rectal biopsies, tumours were poorly differentiated and diagnosis of malignant melanoma could only be established by the complementary immuno-histochemical methods. The first patient had an AP excision of the rectum and died from generalized disease seven months later. In the second case, only palliative irradiation was carried out and the patient died six weeks later. Literature review confirms that rectal melanoma is a very rare tumour. Diagnosis is difficult, especially in the amelanotic forms. Prognosis remains very poor and the best therapeutic approach is still controversial.

Aged↗
PubMedDate not supplied

Primary squamous-cell carcinoma of the colon: a case report.

We report a new case of S.C.C. of the large bowel with multiple liver metastases. A resection of the primary tumour and liver biopsies were performed with administration of a postoperative chemotherapy (5-Fluorouracil). After a stabilization of 3 months, the metastases were rapidly progressive and the patient died a year after the diagnosis. About 70 cases of S.C.C. of the colon and rectum have been described in the literature. It is most common in the fifth decade and occurs equally in male and female. The most frequent locations are the rectum and the sigmoid. Clinical and physical features and common diagnostic methods do not differentiate the S.C.C. from adenocarcinoma. Treatment is the same but the prognosis of S.C.C. appears to be worse than that of adenocarcinoma.

Carcinoma, Squamous Cell↗
PubMedDate not supplied

Two cases of water-melon stomach and a review of the literature.

We report two cases of "water-melon stomach", which is a peculiar form of gastric antral vascular ectasia, characterized by a specific and striking endoscopic aspect. It is observed in a context of chronic iron deficiency anemia and gastrointestinal blood loss, particularly in elderly female patients. The clinical endoscopic, histologic, pathogenic and therapeutic aspects are described, with review of the literature.

Aged↗
PubMedDate not supplied

[Current morphological methods in the study of endocrine tumors and their receptors].

The authors review the recent development of methods aimed at characterizing endocrine tumours. With new immunocytochemical methods, not only specific hormonal peptides can be identified but also hormonal precursors and their sites of processing. Immunodensitometry allows to quantify the hormonal cellular load and to assess hormonal synthesis via the precursors. Finally hormonal receptors can be identified by various techniques of autoradiography.

Endocrine Gland Neoplasms↗