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Biomedical subjects

J Haot

Publications and source records attributed to J Haot.

At least 127 records · Page 7Linked to original sources
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The histopathology of reflux esophagitis.

The histological features of the esophageal mucosa in patients with gastroesophageal reflux are basal zone hyperplasia of the squamous epithelium, elongation of the papillae towards the epithelial surface, an increase in the transverse diameter of the papillae and the blood vessels, and an ingrowth of capillaries into the epithelial layers. The presence of polymorphonuclear leucocytes in the epithelium and the lamina propria clearly represents esophagitis. In the advanced stages, erosions and ulcerations can be seen. Intra-epithelial lymphocytes are present in the normal esophageal mucosa. They are mainly T-cytotoxic lymphocytes.

Animals↗
PubMedDate not supplied

[Acute necrotic hemorrhagic pancreatitis. Major complications (author's transl)].

Forty-four cases of acute necrotic haemorrhagic pancreatitis are studied. Fourteen cases were treated medically by peritoneal dialysis, 20 were treated surgically of which 16 had been medically treated by peritoneal dialysis. Fifteen died or 34%. Forty-one patients, 93.1% presented 8 major complications on admission and 2 complications were observed during the course of medical treatment (pulmonary shock and high digestive haemorrhage). The post surgical complications are excluded from this study. We report in order of frequency; effusion of the large peritoneal cavity (37 cases : 84%), hypocalcaemia less than or equal to 8 mg% (21 cases : 47.7%), renal insufficiency defined by a creatinaemia greater than or equal 2 mg% (17 cases : 38.6%), state of shock (13 cases : 29.5%), severe neurological disorders (11 cases : 25%), peritoneal haemorrhage (3 cases : 4.5%), disseminated intravascular coagulation (1 case : 2.2%), acute rabdomyolysis (1 case : 2.2%). Certain cases are particularly derogatory : pulmonary shock : 2 cases -- 2 deaths (100%); hypocalcaemia less than or equal to 7 mg/ : 6 cases -- 5 deaths (83.3%); acute tubular necrosis : 8 cases -- 6 deaths (75%); hypocalcaemia less than or equal 8 mg% : 21 cases -- 12 deaths (57.1%); high digestive haemorrhage : 3 cases -- 1 death (33.3%); amber known brown peritoneal effusion : 27 cases -- 12 deaths (44.4%); shock : 13 cases -- 5 deaths (38.5%). When in the same patients, less than 3 complications were present, the mortality rate was 20.8%. If more than 3 signs were observed the mortality rate rose to 53.3%. Except for pulmonary shock, six major complications were needed to give 100% mortality rate.

Acute Disease↗
PubMedDate not supplied

[Acute necrotizing hemorrhagic pancreatitis. Surgical treatment (author's transl)].

From 1976 till 1980, 30 patients were operated upon for acute necrotizing hemorrhagic pancreatitis (ANHP). All patients had severe signs of necrosis. Thirty-three operations were performed on these patients: 7 total pancreatectomies, 3 sub-total pancreatectomies, 1 Whipple procedure, 6 left pancreatectomies and 2 caudal-pancreatectomies. Furthermore, 9 patients had an extended sequestrectomy with drainage-lavage, 2 pseudo-cysts were drained into the pancreas and an extended sequestrectomy was performed through the opening in the posterior wall of the stomach; 3 more patients had a simple drainage-lavage of the pancreatic area performed. Twelve patients, among whom 11 with diffuse total ANHP, died after the procedure. The operative indications are discussed together with the possible advantage of using the CT-scan. The therapeutic approach of the biliary ANHP is demonstrated.

Acute Disease↗