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Biomedical subjects

J Ito

Publications and source records attributed to J Ito.

At least 415 records · Page 23Linked to original sources

Adult T-cell leukemia with generalized cytomegalic inclusion disease and pneumocystis carinii pneumonia.

An autopsy case of adult T-cell leukemia with generalized cytomegalic inclusion disease and pneumocystis carinii pneumonia is reported. Tumor cells had T-cell characteristics (E-rosette) and cerebriform nucleus similar to Sèzary cells. Generalized lymphadenopathy, hepatosplenomegaly and an ectopic pancreas in the ileum were found at the time of autopsy. Histologically, leukemic infiltration was observed in almost every organ, and perivascular infiltration, vascular invasion were conspicuous findings. Cytomegalic inclusion bodies were observed in most organs (lungs, salivary glands, pancreas, liver, ectopic pancreas, sweat gland, stomach, thyroid gland, pituitary body, etc.). An acute hepatitis, probably caused by cytomegalovirus, was also noted. Presumed correlation of adult T-cell leukemia, cutaneous T-cell lymphoma and T-cell lymphoma was discussed.

Adult↗

The tumor-forming type of multiple myeloma. I. Biological behavior.

A total of 45 cases of multiple myeloma has been followed up clinically during the period from 7 to 80 months. Out of these, six patients (13.3%) were diagnosed to be the tumor-forming type; they developed discrete tumor formation at the disease onset or during clinical observation. Biological behavior of these cases is briefly outlined. Histologically, five cases presented with well or moderately well differentiated plasma cells according to the grading made by Pasmantier and Azar. The remaining one case was poorly differentiated in cell maturity, and with electron and immunofluorescence microscopies, proved to be of plasmacytic nature.

Aged↗

Bacteriophage phi29 terminal protein: its association with the 5' termini of the phi29 genome.

The location of the protein bound to bacteriophage phi29 DNA has been studied with restriction endonucleases, exonucleases, and polynucleotide kinase. The protein is invariably associated with the two terminal DNA fragments generated by restriction endonucleases. The phi29 DNA prepared with or without proteinase K treatment is resistant to the action of the 5'-terminal-specific exonucleases, lambda-exonuclease and T7 exonuclease. The phi29 DNA is also inaccessible to phosphorylation by polynucleotide kinase even after treatment with alkaline phosphatase. On the other hand, phi29 DNA is sensitive to exonuclease III, and the 3' termini of the DNA can be labeled by incubating with alpha-[32P]ATP and terminal deoxynucleotidyl transferase. The protein remains associated with the phi29 DNA after treatment with various chaotropic agents, including 8 M urea, 6 M guanidine-hydrochloride, 4 M sodium perchlorate, 2 M sodium thiocyanate, and 2 M LiCl. These results are consistent with the notion that the protein is linked covalently to the 5' termini of the phi29 DNA.

Bacillus↗

Studies on the fresh water cercariae in Leyte Island, Philippines. 6. Cercariae from Lymnaeidae and Bulinidae.

In the previous paper of this series, the cercariae from Oncomelania quadrasi (Part 2), from the snails of Thiaridae (Part 3), from the snails of Viviparidae and Pilidae (Part 4), and from Planorbidae (Part 5) were reported continuously. In this paper the crecariae from Lymnaeidae and Bulinidae were dealt with. These studies were all carried on during the period of 1975 and 1976 in Leyte Island, Philippines. From the lymnaeid snails seven species of cercariae, comprising two echinostome cercariae, one fasciolid cercaria, and four xiphidiocercariae were detected. From the bulinid snails, only two xiphidiocercariae were found, both of which were identifiable with those from the lymnaeid snails. These seven species of cercariae are described and illustrated with a tentative name from Cercaria leyteensis no. 37 to Cercaria leyteensis no. 43, in addition with some remarks on their presumptive life histories.

Animals↗

[Convexity cavernous hemangioma, its angiographic and CT findings. Report of a case (author's transl)].

A case of cavernous hemangioma which developed in the parietal convexity is reported. Angiography reveals that the mass is located extra-axially in the parietal convexity and the middle meningeal artery feeds the tumor. The feature of tumor stain is pooling or laking of contrast medium which is partially visualized even 10 minutes after injection of contrast medium. CT findings are almost identical to those of meningioma.

Adult↗