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Biomedical subjects

J J Amy

Publications and source records attributed to J J Amy.

At least 55 records · Page 3Linked to original sources
PubMed1975

Prostaglandin E2 on the electroencephalogram.

Present study was prompted by the report from another center on the occasional occurrence of convulsions and abnormal electroencephalogram (E.E.G.) patterns in women aborted with intra-amniotic prostaglandin F2alpha (PGF2alpha). Fifty four subjects were investigated by means of an E.E.G. taken before and after initiation of PGE2 administration. They included pregnant and non-pregnant patients, nearly half (23) of whom were known epileptics. One seizure was observed during PG administration in a man with daily psychomotor attacks who had not taken his anticonvulsants on the day the test was performed. PGE2 caused no alteration of the E.E.G. in subjects with a normal control tracing; in those with an abnormal E.E.G., a deterioration was seen in one and an improvement in three. It is concluded that PGE2 is not epileptogenic at doses required for termination of pregnancy.

Abortion, Induced↗
PubMed1973

Prostaglandin 15 (R) 15-methyl-E2 methyl ester for suppression of gastric acidity in gravida at term.

During the second hour after giving 100 mug of orally administered prostaglandin 15 (R) 15-methyl-E(2) methyl ester in the pregnant patient at term a noticeable reduction in basal gastric acid secretion took place. At this dose no excessive uterine stimulation was observed. Prostaglandin 15 (R) 15-methyl-E(2) methyl ester could prove of value in the preoperative preparation of the pregnant patient before anaesthesia for reducing the incidence of acid regurgitation.

Esters↗