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Biomedical subjects

J Lucaya

Publications and source records attributed to J Lucaya.

At least 37 records · Page 2Linked to original sources

CT of congenital malformations of the lung.

We reviewed 40 cases of congenital malformations of the lung that were studied with both plain radiography and computed tomography (CT). We compared the CT findings with those of radiography. We found that CT was helpful in the management of these cases because it helped confirm the diagnosis, demonstrated unsuspected findings, and better depicted anatomic extent of anomalies, thus allowing better planning for surgery. We believe that CT is the method of choice for the study of congenital lung malformations and that it should be used before more invasive procedures such as bronchography or aortography.

Bronchogenic Cyst↗

Congenital cystic adenomatoid malformation of the lung. Presentation of 16 cases.

Congenital cystic adenomatoid malformation (CCAM) of the lung is one of the rarest causes of neonatal distress. The principal radiological sign of CCAM is an intrapulmonary mass of soft tissue density, containing cystic areas of different sizes and shapes. The mass usually compresses the rest of the affected lung and displaces the mediastinum and heart to the opposite side, compressing the lung which is often therefore hypoplastic. If CCAM is diagnosed in utero by ultrasound, the treatment of choice is surgery as soon as possible after birth, with good survival rates. Sixteen cases of CCAM are presented, one with bilateral disease, diagnosed at different times, and one with an associated prune belly syndrome, to be added to the 405 already reported in the literature, and their clinical, radiological and pathological features are described.

Diagnosis, Differential↗

Osteofibrous dysplasia. A report of two cases.

Two cases of osteofibrous dysplasia of long bones are reported, one in a neonate with ipsilateral tibial and fibular involvement and the other in a 6-year-old patient with bilateral tibial lesions. The radiological features of the younger patient were remarkably different from those of the older one. These two different and age-related radiological patterns have also been found in most cases previously reported. All the lesions tended to regress spontaneously.

Child↗

Infantile fibrosarcoma of femur.

We describe the clinical presentation and pathological features of an infantile fibrosarcoma of the femur that occurred in a 3 1/2-month-old male infant. The tumor grew rapidly, reaching large size within a few months, finally requiring amputation. The tumor was poorly circumscribed, infiltrating the adjacent soft tissue extensively. Microscopically, it was a highly cellular tumor composed of immature-appearing spindle-shaped cells. Ultrastructural study revealed mesenchymal cells with fibroblastic and histiocytic differentiation.

Bone Neoplasms↗

Computed tomography of infantile hepatic hemangioendothelioma.

Computed tomography (CT) was performed on five infants with hepatic hemangioendothelioma. Precontrast scans showed solitary or multiple, homogeneous, circumscribed areas with reduced attenuation values. Tiny tumoral calcifications were identified in two patients. Serial scans, after injection of a bolus of contrast material, showed early massive enhancement, which was either diffuse or peripheral. On delayed scans, multinodular tumors became isodense with surrounding liver, while all solitary ones showed varied degrees of centripetal enhancement and persistent central cleftlike unenhanced areas. The authors believe that these CT features are characteristic and obviate arteriographic confirmation.

Female↗

[Importance of ultrasound in the study of cerebral pathology in childhood].

Results of 491 studies of the brain with gray-scale sonography in 341 patients with ages ranging from one day to one year are reported. Sonographic appearance of normal brain, cerebral abscesses and hemorrhages in neonates, together with sonographic findings of some congenital brain anomalies are described.

Brain↗

Infundibulopelvic stenosis in children.

Of 11,500 children who underwent excretory urography during a 17-year period, three were found to have the rare renal malformation infundibulopelvic stenosis, characterized by caliceal dilatation, infundibular stenosis, and hypoplasia or stenosis of the renal pelvis. The contralateral kidney was absent in two cases and normal in the other. Voiding cystourethrograms were normal in all three. Renal sonography showed a variable degree of caliceal dilatation without associated pelvic dilatation. The diagnosis was confirmed by retrograde ureteropyelography in one case. Two patients were followed for 12 and 18 months, respectively; both remained asymptomatic with normal renal function, and sequential sonographic examinations of their kidneys have shown no significant changes. The third patient died of an unrelated condition. Infundibulopelvic stenosis has highly characteristic radiographic features, and prognosis is good for most affected patients.

Child↗

Choanal atresia. Report of seventeen cases.

Seventeen cases of choanal atresia are presented, of which 13 were female and 4 male. In 11 patients the malformation was bilateral, being unilateral in the remaining 6; 8 patients also presented other malformations amongst which esophageal atresia and congenital heart disease were the most common. Treatment is surgical, and the prognosis depends largely on the presence or absence of associated malformations.

Esophageal Atresia↗

The Coffin-Siris syndrome. A report of four cases and review of the literature.

Four additional cases of the Coffin-Siris syndrome bring the number of reported cases to 16. This disorder is characterized by the absence or hypoplasia of the nails, especially those of the fifth fingers and toes, growth retardation and mental deficiency, microcephaly, coarse facial appearance, sparse scalp hair and lax joints. Feeding difficulties and respiratory problems are common in infancy. Absence or hypoplasia of the distal and middle phalanges, especially those of the fifth finger and toes and retarded bone maturation are the most common radiological features.

Abnormalities, Multiple↗

[Alterations of skull development in shunt-treated hydrocephalus. Analysis of pathogenic factors (author's transl)].

Skull roentgenograms of 184 children with hydrocephalus treated with shunts were revised. Radiological abnormalities of the skull related to CSF drainage were found in 49,5% of cases. Presence of X-ray abnormalities was correlated with the age of patients at operation, sex, etiology of hydrocephalus, type of shunt device, head circumference at operation and follow-up. Results were submitted to statistical analysis. In this study it is clearly demonstrated that age and head circumference before operation have a strong influence in the pathogenesis of this picture.

Age Factors↗