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Biomedical subjects

J M Brunetaud

Publications and source records attributed to J M Brunetaud.

72 records · Page 4Linked to original sources

The value of endoscopic retrograde opacification of biliary-pancreatic ducts in icterus.

Important progress in the last few years in fiberscopic instrumentation for digestive endoscopy has made possible duodenoscopy with catheterization of the papilla to obtain retrograde biliopancreatic contrast x-rays. Up to now the only possible way to explore biliary ducts, in icterus, was surgically. This new method makes their study possible without any surgical intervention and with a simple neuroleptanalgesia. It is most advantageous in icterus where clinical tests, laboratory tests and other complementary examinations such as laparoscopy do not help to determine the cause. This examination is not devoid of dangers, particularly of the risk of cholangitis and pancreatitis and therefore certain technical precautions are necessary, e.g., immediate surgical intervention in case of organ obstruction and well defined indications.

Cholangiography↗

Lasers in rectosigmoid tumors.

Over a 14-year period, 746 patients were treated at the Lille Laser Center for rectosigmoid tumor. Two hundred seventy-two patients were treated for palliation of symptoms from rectosigmoid cancer and 474 patients were treated for a benign rectosigmoid villous adenoma. The immediate success rate and complication rate were 85% and 2%, respectively, for patients with advanced cancer, and 92.8% and 1.8% for those with a villous adenoma. Patients with an advanced cancer remained functionally improved during a 10.1-month average period after initial improvement. The recurrence rate after initial treatment for villous adenomas was 18% during a 29.7-month average follow-up. Immediate results were influenced by reason for treatment, initial symptoms, and circumferential extension for patients with a cancer, and only by circumferential extension for patients with a villous adenoma. Long-term results were influenced by reason for treatment and circumferential extension for patients with cancer, and by reason for treatment, initial histology and localization for patients with a villous adenoma. Laser treatment provided relief of symptoms in inoperable patients with advanced rectosigmoid carcinomas. Because treatment is long and difficult and the cancer rate is high, endoscopic laser should be limited in patients with a circumferential villous adenoma to non-surgical candidates. The risk of complication after surgery (some being fatal) has to be balanced against the risk of undetected carcinoma and the indication for endoscopic laser treatment should be discussed case by case.

Adenoma, Villous↗

[Laser treatment of rectosigmoidal tumors: long-term results].

Over a 10 year period, 530 patients were treated at the Lille Laser Center for a rectosigmoid tumour. Both argon and Nd:YAG lasers were used. Two hundred patients were treated for palliation of symptoms from a rectosigmoid cancer, 313 patients were treated for a rectosigmoid villous adenoma, and 17 patients with a familial polyposis were treated for the rectal polyposis remaining after total colectomy. The immediate success rate and complication rate were 88% and 2.7%, respectively, for patients with advanced cancer, 92% and 2% for those with a villous adenoma, and 100% and 0% for those with polyposis. Patients with an advanced cancer remained functionally improved during a 10.1 month average period after initial improvement. The recurrence rate after initial treatment for villous adenomas was 14% during a 3.1 year average follow-up. Immediate results were influenced by reason for treatment, initial symptoms and circumferential extension for patients with a cancer, and only by circumferential extension for patients with a villous adenoma. Long term results were influenced by reason for treatment and circumferential extension for patients with a cancer, and by reason for treatment, initial histology and localization for patients with a villous adenoma.

Adult↗