Biomedical subjects
Publications and source records attributed to J Noone.
Table 2 provides an overview of the classifications of antiarrhythmic agents, their actions, and their uses against reentrant arrhythmias and those caused by enhanced automaticity. Table 3 reviews many of the differences between the two mechanisms of arrhythmias: enhanced automaticity and reentry. Clinical distinction will assist in the most appropriate choice of therapy for terminating cardiac arrhythmias.
Binding (or interaction) of cortisol with microbial molecule(s) was observed by employing Bio-Gel HTP affinity chromatography and subsequently by fluorescence spectrophotometry. Molecule(s) in the crude extract of baker's yeast and in other microbial proteases exhibited varied degrees of cortisol-binding. Bacterial protease (type IX) had highest, while the type XXVI enzyme had the lowest, binding capacity. In addition, these two proteases exhibited a distinct difference in the alterations of ultraviolet spectra due to interaction with cortisol. Using casein as a substrate, cortisol, CTP, trypsin inhibitor or leupeptin appreciably inhibited type IX protease at low concentrations of Ca2+. However, thyroxine had no effect on this protease.
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Acquired Immune Deficiency Syndrome (AIDS) has made a wide impact not limited to those persons who have or are likely to contact it. A case history of a man with a near-delusional belief he had AIDS is presented to exemplify the individual issues that concern about AIDS may raise. Thorough exploration of the dynamic interplay of biological, psychological and social factors is recommended in each case before reassurance may be effective. Psychiatric consultation should assist in developing optimal intervention in each individual case.
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