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Biomedical subjects

J Nowicka

Publications and source records attributed to J Nowicka.

At least 37 records · Page 2Linked to original sources

Hall effect transducer for apexcardiography and sphygmography.

Recording of mechanograms (Recording of mechanical activity of internal organs and vessels, often non-invasively eg. apex cardiogram) can be performed by applying different kinds of mechano-electric transducers. In this paper the idea and construction of a new transducer with Hall-generator are presented. This transducer is self-adjusting in the range of its linear characteristics, and exerts practically constant touching pressure independent of the configuration of the patients thorax. This facilitates the measuring process and allows for calibration of the obtained records. The sensitivity of the transducer is 250 mV/mm, frequency bandwidth 0-45 Hz and it has a linearity of +/- 1.5% in the range of displacements +/- 1.5 mm. The transducer also generates the signal of the first derivative of the investigated vibrations. Assessment of the transducer was carried out in a cardiology clinic on 27 patients with a normal heart and with different kind and degree of heart damage. The mechanograms obtained from different transducers for each patient were compared in respect of the essential time intervals and morphological elements. The comparison shows a good detecting capability, correctness and reproducibility of the data obtained by means of the Hall-effect transducer. Some recordings of mechanograms (apexcardiograms and different kinds of pulse) from patients with normal heart, valvular aortic stenosis and atrial heart defect are shown and discussed in the paper.

Heart Diseases

Intravascular coagulation and fibrinolysis syndrome (ICF) in acute non-promyelocytic leukemia.

Three cases of acute non-promyelocytic leukemia complicated with intravascular coagulation and fibrinolysis syndrome were described. The blood clotting system and fibrinolysis studies in all 3 cases revealed a significant increase of FDP level and shortening of fibrinolysis time as well as a decrease of fibrinogen content in 2 cases. In one patient the recovery from ICF syndrome and complete acute leukemia remission of 8 months duration was obtained. The further 2 cases failed to improve: in one of them the ICF syndrome appeared in relapse of acute myelocytic leukemia after 2 years of its duration and in the remaining one acute undifferentiated cell leukemia of fulminating course developed in the patient suffering from bone marrow aplasia.

Adolescent

[Lysozyme activity in the saliva of industrial workers exposed to fluorine compounds].

The authors performed investigations in Phosphoric Fertilizers Works in Gdańsk to find out whether or not the work environment contaminated by fluorine compounds affects the activity of lysozome--the protective enzyme of saliva. In some in vitro experiments lysozome activity in exposed workers' saliva was found to be significantly lowered, as opposed to that in unexposed workers. In vivo experiments did not indicate any effects of work conditions on the activity of this enzyme. The obtained results, in vivo and in vitro, do not demonstrate any clear effects of work environment in the Phosphoric Fertilizers Works in Gdańsk, upon lysozome activity in workers' saliva.

Adult