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Biomedical subjects

J Pandey

Publications and source records attributed to J Pandey.

At least 37 records · Page 2Linked to original sources
PubMed1994

Evaluation of two techniques (RPHA and latex agglutination) for use as a screening tool for HBsAg.

RPHA and latex agglutination are two cost effective techniques available for HBsAg screening in our country. Most of the blood banks and other clinical laboratories use RPHA technique or latex agglutination test for screening of donors or patients positive for Hepatitis B surface Ag (HBsAg). All the reagent kits available in the Indian market do not give the ranges of specificity, sensitivity and predictive values for the particular test. Also no data is available if they were tested on Asian sera. Therefore it was decided to evaluated the two most often used techniques RPHA and latex agglutination for their sensitivities and efficacy as a screening test. Our results indicate that though RPHA may be used in a diagnostic set up, it is a poor screening tool as it gives a fairly large number of false negatives and has a low sensitivity. Latex agglutination on the other hand, does not give any false negative results and is recommended for preliminary screening, wherever cost is a constraint. The sera with positive results should be subsequently tested by EIA to rule out the false positive results.

Hemagglutination Tests↗
PubMed1993

Aspiration cytology of maxillary myxoma.

Fine-needle aspiration was used to diagnose a case of maxillary myxoma. Abundant mucoid material was obtained. Microscopic examination showed three-dimensional fibrillary myxoid fragments entangling spindle-shaped, stellate, and fusiform cells with round to oval monomorphic nuclei. A striking feature was delicately branching capillaries. The diagnosis was subsequently confirmed on histology and histochemistry.

Adult↗
PubMed1993

Diagnostic value of maternal serum alpha fetoprotein for predicting pregnancy outcome in high risk pregnancies: an epidemiological perspective.

This study was conducted on high risk pregnancies, between 6-40 weeks of gestation, to evaluate the difference in maternal serum alphafetoprotein (MSAFP) levels in normal and abnormal pregnancies. It's predictive value for pregnancy outcome was calculated. Age and parity matched, normal pregnant women with normal pregnancy outcome were taken as controls. It was determined that the overall sensitivity (75.6%) and specificity (83.7%) was not very good for diagnostic purposes. On the contrary in patients with neural tube defects, congenital anomalies, early pregnancy complications leading to fetal death, still birth, neonatal deaths, Rh incompatibility and preterm deliveries the specificity was (96%-100%), due to very few false positives but sensitivity was comparatively low (75%-89%) due to many false negatives. As a result the predictive value of a negative test in these conditions was very high (80%-100%), though that of a positive test was comparatively low (60%-89%). This establishes a diagnostic value of MSAFP, especially in high risk pregnancies as opposed to its use as a screening test for all pregnancies. This is of special value for a poor country like India, where it is not possible to screen total pregnant population due to economic and logistic reasons.

Adolescent↗
PubMed1993

A simple screening procedure for detection of infraclinical cases of multiple myeloma.

Agarose Gel Serum Electrophoresis is a simple, rapid and sensitive technique routinely used for diagnosis of Multiple Myeloma. Its effectiveness as a screening tool for detecting infraclinical cases of Multiple Myeloma is brought out in this study. 29 out of the 219 patients presenting with unexplained osteoporosis and pain are found to be positive for M proteins. These patients were earlier adjudged organic disease free after preliminary investigation and examination.

Adult↗
PubMed1993

Blood safety.

Explore the source record for details and available documents.

Blood Banks↗
PubMed1993

Computerisation of blood bank services of a large hospital.

A comprehensive computer aided management scheme for Blood Bank of a large hospital is presented. The hardware requirement and networking pattern are simple flexible and cost effective to suit any kind of needs. Details of the modular software program are discussed. The advantages of the modular program is its flexibility and expandability, to suit not only the needs of a Blood Bank but also the whims and fancies of the personnel working in it. The program is completely portable and operates in an MS DOS environment on a IBM or compatible machine. The solutions are simple and cost-effective, a feature of particular importance to setups which have the technological capability but do not have the economic feasibility. The approach and software features are discussed in detail in order to make it possible for any one to develop similar system if desired.

Blood Banks↗
PubMed1990

Social support as a moderator of the relationship between poverty and coping behavior.

This study examined the relationship between poverty and coping and defense behaviors and the way social support moderates this relationship. One hundred fifty Indian adults responded to scales of income, perceived economic status, coping, defense and social support. In addition, physical quality of living was rated on the basis of observation and a short interview. Results showed that income and physical quality of living were positively associated with perceived economic status. Income, physical quality of living, and perceived economic status were negatively related to coping and defense behaviors. Finally, social support did not moderate the impact of poverty on coping and defense behaviors.

Adaptation, Psychological↗