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Biomedical subjects

J Robillard

Publications and source records attributed to J Robillard.

At least 37 records · Page 2Linked to original sources
PubMed1978

Arginine vasopressin response to an osmotic stimulus in the fetal sheep.

Baseline plasma osmolality (pOsm) and plasma arginine vasopressin (pAVP) were measured in chronically catheterized fetal sheep. Mean baseline pAVP in fetuses from 101-120 days was 1.9 +/- 0.46 muU/ml (mean +/- SEM) with a pOsm of 293 +/- 1.8 mOsm/kg. In fetuses of 121-141 days of gestation, mean pAVP was significantly lower, 0.77 +/- 0.19 muU/ml (P less than 0.05), with a similar pOsm (293 +/- 1.9 mOsm/kg). The logarithmic baseline pAVP values were linearly correlated with pOsm for both groups. Hypertonic saline infusion resulted in a similar increase in the log pAVP corrected for the rise in pOsm in the 101-120-day fetuses and in 121-141-day fetuses. The slope of this response was similar to that of the steady state relationship. The data indicates that the fetal osmoreceptor system for control of arginine vasopressin secretion is fully functional in the last trimester of pregnancy.

Animals↗
PubMed1977

[Scanning of bone metastases (author's transl)].

The Centers against cancer of Caen, Angers, Montpellier, Strasbourg and "the Curie Foundation" have confronted their experience in detection of bone metastases by total body scanning. From the investigation by this procedure, of 1,467 patients with cancer, it results: --the confrontation between radio and scanning shows a rate of false positive and false negative identical to the literature ones; --the countage scanning allows to reduce the number of false positive; --scanning allows to direct bone biopsy and to improve efficiency of histological examination.

Bone Neoplasms↗
PubMed1977

[Time factor in local radiotherapy (author's transl)].

This study was aimed at determining the influence of time factor in local radiotherapy in patients with spindle cell neoplasms of the skin or basal cell carcinomas of the face, treatable in a single plane. These neoplasma were treated using identical doses (6,000 rads distributed over the envelope isodose), but divided at random into two groups corresponsing to two different spreads (60 +/- 12 hours and 156 +/- 12 hours). The biological effects observed (rate of disappearance of the lesion, intensity of skin reaction, duration of skin reaction) showed no difference between the two types of treatment. This results is unexpected considering the important influence of time factor in the case of fractionated irradiation. In fact, if it is accepted that between 60 and 156 hours, cellular multiplication phenomena are equivalent to approximately 30 rads per day, the difference in spread the two types of treatment is not sufficient to give a significant result.

Basal Cell Carcinoma↗
PubMed1976

[Non-surgical treatment of tuberous angiomas of the lip. Apropos of 26 cases].

Among the various methods that can be used for the treatment of hemangiomas of the face, the use of Yttrium 90 radium needles seems to give the most satisfactory esthetic results. One application is usually sufficient to obtain disappearance of the tumor. Spontaneous regression is now a generally accepted fact, however, and the essential problem remains whether hamangiomas should be treated all when no complications are present.

Child, Preschool↗
PubMed1976

[A quantitative and quanlitative examination of bone metastases by whole body scanning with 99mTc-pyrophosphate (author's transl)].

The purpose of the present work is to "quantify" bone scanning, in order to calculate indices of localized uptake that will make it possible to differentiate between normal and pathological uptake, and approach an etiologicial diagnosis. The authors use an Elscint dual head whole body scanner and an offline video display calculator. The patient is given 8 mc technetium 99m pyrophosphate 4 hours prior to scanning. The whole body count is expressed in thousands of counts multipled by two so that the knee to whole body ratio is close to one, to facilitate comparison of the indices. Results show that the presence of metastases is demonstrated more clearly by using a ratio bone segment to whole body. Quantitative scanning with 99mTc-pyrophosphate makes it possible to: 1) detect bone metastases easily, 2) follow the metastases during treatment, 3) avoid the gross errors that can be made in nomquantitative scanning.

Bone Neoplasms↗
PubMed1976

[Adaptation of an A.G.S. endo-uterine catheter for hysterographic examination during radium therapy (author's transl)].

The authors propose an endo-uterine catheter which will permit a hysterographic examination to be made during utero-vaginal radium therapy, thus making it possible to check: --that the catheter has advancec correctly after insertion; --that the uterine cavity intact: --that the catheter is in the correct place; --its retention during treatment. By using radio-opaque rings and small balloons in the hysterographic examination, it is possible to locate: --the external orifice of the cervix; --the urethral meatus; --the anterior wall of the rectum and the posterior wall of the bladder. In this way, the target volume is loated with precision, and the length, position and activity of the various radio-active sources can be adapted accordingly.

Catheterization↗