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Biomedical subjects

J Rotgans

Publications and source records attributed to J Rotgans.

23 records · Page 2Linked to original sources

[Antimicrobial properties of cements with and without copper content].

Copper-containing cements seem to inhibit bacterial growth better than copper-free materials. Twenty-four hours after insertion, a statistically significant difference is noted. The initial bactericidal effect of copper-free cements declines considerably as compared to copper-containing cements. The results obtained largely correspond to those given in the literature. The method used of including bacterial suspension in a liquid medium is suitable to establish dose-reaction curves for dental materials.

Copper

[The effect of amyloglucosidase and glucoseoxydase containing toothpastes on plaque formation and gingivitis].

Earlier studies showed that an antibacterial lactoperoxydase system in the saliva is activated by the application of a hydrogen paroxide-generating combination of enzymes: amyloglucosidase and glucose oxydase. The object of the present study was to investigate the effect of these enzymes in a test and control group of 29 subjects. The results showed the plaque-inhibiting effect of the enzyme paste. An influence on the gingiva could not be demonstrated.

Dental Plaque

[Maturation of mammalian bone minerals. A new method for determining bone metabolism].

The present report begins by comparing data on bone mineralization communicated in the literature to date with the authors' own previously published concept of the "three-phase model". The age-dependent accumulation of minerals in the femurs of Wistar rats was also chemically-analytically investigated. The results suggest that the mineral first formed is octacalcium phosphate. It is followed by sodium- and magnesium-containing phases. Maturation of octacalcium phosphate only occurs after this; it is converted into a highly carbon-deficient hydroxyapatite. During this conversion the molar Ca/P ratio rises from 1.33 to 2. However, the final value of 2 is not fully attained: this is attributable to the "turnover" activity of bone-metabolic processes. The paper concludes with a discussion of how the newly developed chemical method of determining bone turnover can be used to determine its vitality.

Animals