Biomedical subjects

J Ryś

Publications and source records attributed to J Ryś.

44 records · Page 3Linked to original sources

PubMed1989

[Presence of lysozyme and alpha 1-antichymotrypsin in tumors of the fibrous histiocytoma type. Immunohistochemical evaluation of 52 cases].

In 52 cases of fibrohistiocytic sarcoma activity of alfa-1-antichymotripsin (ACT) in tumour cells was found in 47 cases and lysozyme in 16 cases. ACT was found in all types of tumour except angiomatous. Lysozyme was positive only in pleomorphic type, all these cases have also activity of ACT. Investigated enzymes are useful in diagnosis with correlation to others markers used in diagnostic procedure of soft tissue tumours.

Adult↗

PubMedDate not supplied

Expression of the c-erbB2 proto-oncogene in male breast carcinoma: lack of prognostic significance.

Increase of gene activity of the proto-oncogene erbB2 which codes for the transmembrane kinase receptor p185erbB2 has been observed in > 30% of female breast and gynecological carcinomas. This overexpression was shown to be correlated with poor prognosis. We have investigated 38 samples of carcinomas of the male breast for p185erbB2 expression by using tumor thin sections and a monoclonal antibody. The immunostaining was compared to clinical data to assess a possible prognostic value of this parameter. Although most cases were immunopositive (36/38), no correlation to tumor grading and survival spans was notable. Therefore, erbB2 activity fails to add a new prognostic parameter in male breast carcinomas.

Biomarkers, Tumor↗

PubMedDate not supplied