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Biomedical subjects

J S Hsieh

Publications and source records attributed to J S Hsieh.

At least 55 records · Page 3Linked to original sources
PubMed1987

Intraperitoneal hemorrhage due to spontaneous rupture of hepatocellular carcinoma: treatment by hepatic artery embolization.

Seventeen patients with intraperitoneal hemorrhage due to spontaneous rupture of hepatocellular carcinoma were treated by emergency transcatheter arterial embolization. Fine-needle aspiration cytology was used to establish the histologic diagnosis in 11 patients with no history of hepatic malignancy. The other six patients had a pathologic confirmation of hepatic malignancy by open biopsy before admission. Pretreatment angiography showed extravasation of contrast material from the hepatic tumor in four patients (24%). In the other 13 patients, only hypervascular tumors were seen. Successful hemostasis was achieved in all patients. Fourteen patients survived after the embolization; the other three died immediately after embolization. Of the 14 patients, 11 died later (survival time ranged from 16 to 386 days). The remaining three patients are still alive at 3, 7, and 15 months, respectively, after the procedure. No serious complications related to embolization were encountered. Most patients had pain and fever. We conclude that emergency arterial embolization is an effective alternative to surgery for hepatic hemostasis in patients with spontaneous rupture of hepatocellular carcinoma.

Adult↗
PubMed1986

Demonstration of rectal varices by transhepatic inferior mesenteric venography.

A case of rectal varices confirmed by percutaneous transhepatic inferior mesenteric venography is reported. By using the transhepatic approach, the mesenteric venous tributaries can be catheterized selectively with direct injection of the high-density dye, and the location and extent of varices are clearly demonstrated. Transhepatic inferior mesenteric venography can be used as an alternative method of angiographic investigation for rectal varices.

Gastrointestinal Hemorrhage↗
PubMedDate not supplied

Portographic evaluation for recurrent esophagogastric varices following devascularization surgery.

PURPOSE: To investigate, by transhepatic portography, the changes in portosystemic collaterals and recurrent esophagogastric varices after devascularization surgery. METHODS: Thirty-five patients, who had undergone devascularization surgery 2-8 years previously, underwent follow-up portography and the collaterals and drainage routes were compared with preoperative portography results. RESULTS: Newly formed collaterals were present in 30 of 35 patients and the origins and drainage routes differed from preoperative ones. Most common were new collaterals arising from the junction of the portal and superior mesenteric veins; the next most frequent arose from a main portal branch, the portal trunk, or the superior mesenteric vein. New collaterals with recurrent varices were seen in 20 patients and without varices in 10; 5 patients had no collaterals or varices. CONCLUSION: Since the development of new collaterals is common in portal hypertensive patients following devascularization surgery, regular follow-up for recurrent varices is necessary.

Adult↗
PubMedDate not supplied

Endoscopic ultrasonography for preoperative locoregional staging and assessment of resectability in gastric cancer.

We performed a prospective study from November 1989 to December 1996 to assess the accuracy of endoscopic ultrasonography (EUS) in the locoregional staging and resectability of patients with gastric carcinoma. One hundred and nineteen patients with gastric cancer who received preoperative assessment by EUS underwent subsequent surgery. The endosonographic tumor-node-metastasis (TNM) classification was used for comparison with the histopathologic findings of the resected specimens. The ability of EUS to accurately predict the T stage (depth of tumor invasion) and N stage (involvement of lymph node) was 70% and 65%, respectively. EUS displayed a tendency to overestimate T stage and underestimate N state. The differentiation of early gastric cancer from advanced gastric cancer showed a concordance rate of 89% and underestimation rate of 8% and underestimation rate of 3%. The accuracy of EUS in predicting the stage T1 to T3, which correspond to D0 resectability (no macroscopic or microscopic tumor remains), was 91%. In conclusion, these results revealed EUS as a valuable tool for evaluating the local staging and resectability of gastric cancer. We suggest that EUS should be introduced in the preoperative assessment of patients with gastric cancer.

Adult↗
PubMedDate not supplied

The effect of portal hypertension on gastric epithelial proliferation in rats.

We investigated the effect of portal hypertension over time on gastric epithelial proliferation in rats. Portal-vein ligation (PVL) was applied to fourteen Wistar rats to produce experimental portal hypertension: seven rats (PVL2) had histological analysis after 2 months and the remaining seven (PVL4) after 4. An additional group of seven was employed as a control. Each rat was injected with bromodeoxyuridine and killed an hour later to assess gastric epithelial proliferation by an immunohistochemical staining technique. The labeling index between PVL and control animals differed significantly (p < 0.05). Labeling indices in fundic mucosa were 5.7 +/- 0.2% in controls, 3.9 +/- 0.3% in PVL2 rats and 4.0 +/- 0.3% in PVL4 rats, while in antral mucosa the corresponding figures were 7.5 +/- 0.6, 4.6 +/- 0.3 and 4.0 +/- 0.3%. In neither fundic nor antral mucosa was the total mucosal thickness significantly different between the control and PVL rats. In the PVL2 group, the frequency distribution of labeled cells showed a shift toward the mucosal surface in fundic glands. No significant differences between the two PVL groups were observed in any of the studied parameters. This study suggests that portal hypertension may inhibit gastric epithelial proliferation in rats.

Animals↗