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Biomedical subjects

J S Sim

Publications and source records attributed to J S Sim.

59 records · Page 4Linked to original sources
PubMedDate not supplied

Detection of segmental branch renal artery stenosis by Doppler US: a case report.

In stenosis of a segmental branch or among multiple renal arteries, Doppler sampling of intrarenal arteries in the upper, mid and lower poles demonstrates strikingly different waveform patterns that might otherwise be overlooked. We report a case of segmental branch renal artery stenosis in which a pulsus parvus et tardus waveform was observed in a segmental branch of a renal artery. In this case, systematic analysis of Doppler waveforms of intrarenal arteries at more than three different locations facilitated a rapid and confident diagnosis of segmental branch renal artery stenosis.

Adult↗
PubMedDate not supplied

Effects of excess vitamin D3 and cage density on the incidence of leg abnormalities in broiler chickens.

A 2 X 2 factorial experiment was designed to investigate the effects of excess vitamin D3 and cage density on the incidence and severity of leg abnormalities in broiler chickens. One hundred eighty 1-day-old broiler chicks were randomly divided into densities of either 10 (680 cm2/chick) or 20 (340 cm2/chick) per cage and fed a diet containing 22% protein and 2879 kcal/kg metabolizable energy formulated to meet National Research Council requirements. Two levels of vitamin D3 were incorporated to supply either 400 ICU or 4000 ICU/kg feed. High density and excess vitamin D3 resulted in a significant (P less than 0.05) increase in the incidence of twisted leg. Differences in incidence could not be explained through differences in body weight or feed consumption. However, broilers fed the excess vitamin D3 consumed more feed but gained less body weight, suggesting that metabolic stress may have been involved. High density appeared to increase the severity of the disorders, whereas excess vitamin D3 had no effect on severity.

Animals↗
PubMedDate not supplied

Morphometric and radiographic characteristics of tibial bone of broiler chickens with twisted leg disorders.

Tibiae from normal broiler chickens were compared with those from broilers displaying twisted leg in an attempt to develop a pattern recognition for the disorder. Qualitative differences were determined using conventional radiography, and quantitative differences were determined using sequential morphometry. Sequential radiography revealed that twisted leg developed from a slight deviation or torsion of the distal tibiae. Progressive bowing of the tibiae and compensatory thickening of the cortex on the weight-bearing side were characteristic radiographic features of twisted leg and were most likely a functional adaptation to the disorder. Sequential morphometry suggests that the development of twisted leg in broilers may be related to a structural abnormality in the distal tibiae, namely shallow distal condyle grooves. Shallow distal condyle grooves may predispose the distal tibiae to a slight displacement of the gastrocnemius tendon and hence uneven strain on the distal condyles. Other changes in tibial morphology (diameter at midshaft, condylar width, cortical thickness) appeared to be functional adaptations to the deformation rather than the primary cause.

Animals↗
PubMedDate not supplied

Consumption of n-3 polyunsaturated fatty acid-enriched eggs and changes in plasma lipids of human subjects.

The cholesterolemic effect of chicken eggs enriched with n-3 polyunsaturated fatty acids (PUFA) was investigated in healthy volunteers. Twenty-three male university students consumed two regular or n-3 PUFA-enriched eggs per day with their habitual diet for 18 days. Plasma total cholesterol (TC) and low-density lipoprotein cholesterol (LDL-C) levels were raised in subjects who consumed regular eggs but were maintained virtually unchanged in those who consumed n-3 PUFA-enriched eggs. Intake of two regular eggs a day did not affect plasma high-density lipoprotein cholesterol (HDL-C) and plasma triglyceride (TG) levels, but intake of two n-3 PUFA-enriched eggs a day resulted in a significant elevation in HDL-C (p < 0.05) and a reduction in plasma TG (p < 0.01). Consuming regular eggs tended to decrease both HDL-C/TC and HDL-C/LDL-C ratios, whereas consuming n-3-enriched eggs tended to increase them. The n-3 PUFA contents in plasma lipids of subjects who consumed n-3 PUFA-enriched eggs were also found to be elevated. These results demonstrate that the cholesterolemic property of chicken eggs can be modified by altering the fatty acid composition of yolk lipids.

Adolescent↗