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Biomedical subjects

J T Møller

Publications and source records attributed to J T Møller.

At least 37 records · Page 2Linked to original sources
PubMed1988

Midazolam combined with paracervical blockade compared to general anaesthesia for curettage of the uterus.

Two anaesthetic techniques were compared in a randomized trial of 60 ASA I and II women admitted for diagnostic dilatation and curettage of the uterus. Group I had fentanyl 2.5 micrograms/kg and thiopentone 2 mg/kg i.v. Supplementary thiopentone 50 mg was given every 15 s until loss of the eyelid reflex. Anaesthesia was maintained with nitrous oxide in oxygen 2/1 together with supplementary thiopentone 50 mg as required. Group II had midazolam 0.1 mg/kg i.v. and a supplementary 0.025 mg/kg every second min until sleep or dysarthria, followed by paracervical blockade with 1% mepivacaine 10 ml on each side of the portio. There was no significant depression of the cardiovascular system. The working conditions for the gynaecologist were good in both groups. The midazolam technique gave just as good amnesia as did general anaesthesia, and there was a high degree of patient satisfaction in both groups. In the thiopentone group there was a significant depression of the respiratory rate and a significantly higher frequency of adverse effects (nausea and vomiting) as compared to the midazolam group. It is concluded that paracervical blockade combined with midazolam, titrated i.v., until sleep or dysarthria, is a recommendable anaesthetic technique for diagnostic dilatation and curettage.

Anesthesia, General↗
PubMed1987

A comparison between two emergency cricothyroidotomy instruments.

As part of a training programme for younger doctors, two commercially available, emergency cricothyroidotomy sets were evaluated. Prior to the surgical procedure, half of the doctors in each group received an audiovisual lesson. In a simulated but realistic emergency situation, involving autopsy material, cricothyroidotomy was performed utilizing either the "Nutrake" or the "Gentofte" system. The audiovisual lesson increased the speed and the success rate of the doctors performing this procedure as well as strengthening their confidence. Both systems allowed positive pressure ventilation. The participating doctors achieved a higher success rate at a faster speed with the "Nutrake" set.

Catheterization↗
PubMed1986

Fibrin sealant in bone transplantation. No effects on blood flow and bone formation in dogs.

To study bone formation and regional blood flow following the use of fibrin sealant in autologous cancellous bone transplantation, a dog model was developed. In 18 dogs, a standardized defect in both tibiae was filled with an autologous iliac crest graft. On one side, the bone chips were mixed with fibrin sealant while the other side served as control. After 1, 2 and 3 weeks the blood flow of the transplant was calculated and the new bone formed evaluated histomorphometrically. Generally, the highest blood flow rates and most intensive new bone formation were observed at 2 weeks postoperatively. Fibrin sealant did not alter blood flow or new bone formation, but a tendency to diminished new bone formation was found in some grafts. Our study does not support the application of fibrin sealant in ordinary cancellous bone grafting.

Animals↗
PubMed1985

Tibial plateau strength patterns in experimental modular knee replacement.

Nondestructive low-strain-rate compression tests were carried out on 12 human cadaver tibiae fitted with a metal modular resurfacing component on the medial or lateral condyle. The tests were done at 20 regularly spaced points on each plateau. The reproducibility of measurement was +/- 16% (95% tolerance limits). A statistically significant correlation was demonstrated between stiffness and ultimate force values obtained from the same points (r = 0.75, P less than 0.005). On the medial plateau the compressive stiffness of the system was maximal when load was applied to the center of the prosthesis, but declined sharply toward the medial and posterior margins. On the lateral plateau maximal stiffness values were obtained more posteriorly, and the stiffness gradients toward the periphery were less marked. Details of surgical technique and specific loading situations that may cause undesirable combinations of load and point of prosthetic component contact are discussed.

Biomechanical Phenomena↗
PubMed1985

Unicompartmental arthroplasty of the knee. Cadaver study of tibial component placement.

In 30 knee preparations the median posterior inclination (tilt) of the medial tibial plateau was 10 degrees (5 degrees-15 degrees). Following medial compartmental arthroplasty in 20 knees, 10 with horizontal, and 10 with 10 degrees tilted tibial components, the point of articulation was determined radiographically. For the combinations of tibial angle and knee flexion that represent the initial 60 per cent of the stance phase, articulation took place more posteriorly on the horizontal components; there was a correlation between the operation-induced change of the tibial inclination and articulation. Articulation took place far posterior on horizontal components inserted in knees with a steep posterior tilt. We concluded that both the component placement and the preoperative inclination of the tibial plateau determine where on the tibial component articulation takes place. An optimal, central articulation with this set-up is obtained when the component is inserted with the same posterior tilt as that of the original articular surface.

Biomechanical Phenomena↗
PubMed1985

Unicompartmental arthroplasty of the knee. Cadaver study of the importance of the anterior cruciate ligament.

The tibiofemoral articulation on horizontal and 10 degrees tilted tibial components was examined radiographically in 20 cadaver knees after lateral arthroplasty, and after cutting the anterior cruciate ligament in 10 knees with medial and 10 with lateral arthroplasty. Articulation took place more posteriorly on the horizontal components at any degree of flexion examined; a correlation was found between the operation-induced change in the inclination of the lateral tibial plateau and the point of articulation. Based on the regression equations, the expected point of articulation on an arbitrarily chosen component placement could be calculated for any degree of flexion provided the preoperative inclination was known. Cutting the anterior cruciate ligament caused articulation to move posteriorly on the tibial component at both medial and lateral arthroplasty. We concluded that it was possible to estimate the tilt of the tibial component that was required to avoid marginal articulations when the preoperative slope of the tibial plateau was known. Absence of the anterior cruciate ligament seems to contraindicate unicompartmental arthroplasty.

Biomechanical Phenomena↗
PubMed1984

Occupational accidents and alcohol.

Alcoholic intoxication is commonly considered to be an important cause of occupational accidents. Over a period of one year the alcohol concentration in the breath and/or blood was studied in 5439 patients, who, following an occupational accident, attended the emergency departments of a large Danish provincial city. It is concluded that only a few, apparently less than 3%, were inebriated in the legal sense of the term (BAC above 0.8%) at the time of the accident.

Accidents, Occupational↗