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Biomedical subjects

J Tada

Publications and source records attributed to J Tada.

100 records · Page 6Linked to original sources
PubMed1981

[Use of cefroxadine dry syrup in the management of acute skin infections in children (author's transl)].

1. Cefroxadine dry syrup was in principle administered at the dosage of 10 mg per kilogram of body weight 3 times a day. 2. Evaluation was done in 4 grades, i.e. excellent, good, fair and poor. 3. According to subjective judgement by attending doctors, 'excellent' or 'good' was recorded in 90.7%. 4. If the evaluation was partially standardized, 'excellent' or 'good' was obtained in 74.8% of total 163 cases and in 78.7% of 108 impetigo cases. 5. Side effects were observed in 3 cases (diarrhea 1, fever 2). No direct correlation of these complaints with the administration of the present drug was confirmed.

Abscess↗
PubMed1981

Cholesterol synthesis and esterification in experimental xanthoma tissues.

We studied cholesterol metabolism in experimental xanthoma tissues which were induced by injection of high molecular weight sodium dextran sulfate into the dermis of hypercholesterolemic rabbits. Control studies were performed on dermal specimens of the dextran sulfate-injected site of normolipemic rabbits. Cholesterol accumulation was much greater in the hypercholesterolemic rabbit tissues than in the normolipemic rabbit tissues. Histiocytes and foam cells in such lesions had an ability to synthesize cholesterol. However, cholesterol synthesis was suppressed in the cholesterol-rich tissues of hypercholesterolemic rabbits. This suppression was obviously caused by the accumulation of cholesterol in the tissues which take up lipoprotein in hypercholesterolemic rabbits. On the other hand, esterification of cholesterol was greater in the hypercholesterolemic rabbit tissues than in the normolipemic rabbit tissues. Cholesterol was esterified more selectively with oleic acid than with palmitic acid. Therefore, cholesteryl oleate increased in the tissues concomitantly with the accumulation of cholesteryl esters. Fatty acids of serum origin rather than those synthesized in situ were more important in the esterification process. It was suggested that cholesterol esterification was mediated by acyl-coenzyme A:cholesterol acyltransferase and that lecithin:cholesterol acyltransferase contributed little to the process.

Animals↗
PubMedDate not supplied

Compensation for beam intensity fluctuation in determination of P(ion) the ion-recombination correction factor for ionization chambers, by the two-voltage technique.

We have developed a method of compensation for fluctuations in beam intensity that may occur during measurement of Pion, the ion-recombination correction factor, by the two-voltage technique. The method requires signals proportional to beam intensity during measurement. We used a parallel-plate ionization chamber, whose Pion was known, and a vacuum chamber to obtain signals that were proportional to the beam intensity. Experiments were conducted using pulsed proton beam providing doses that ranged from 0.16 to 0.01 cGy/pulse. The value of Pion of a thimble ionization chamber was measured. With these measurements, the validity of the method which we proposed for pulsed beam was verified experimentally.

Particle Accelerators↗
PubMedDate not supplied

Time resolved properties of acoustic pulses generated in water and in soft tissue by pulsed proton beam irradiation--a possibility of doses distribution monitoring in proton radiation therapy.

Time-resolved acoustic pulses generated in water and in soft tissue by pulsed proton beam irradiation were observed. The spatial resolution of depth dose distribution in the clinically applied beam intensity is estimated about 3 mm by means of TOF measurement. The dependence of the acoustic signal intensity on the temperature of medium was examined. Proportionality of acoustic pulse intensity to absorbed dose per pulse was confirmed as well. These results suggest the possibility of clinical application to monitor dose distribution in the patient's body during irradiation of pulsed proton beam.

Humans↗