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Biomedical subjects

J Tomala

Publications and source records attributed to J Tomala.

At least 19 recordsLinked to original sources
PubMed2000

[Pregnancy outcome in women after ovulation induction].

UNLABELLED: The study was performed in 116 pregnant women after ovulation induction in 1995-1999. The pregnancy outcome was analysed. In 92 of 116 women (79.3%) successful outcome ("home taken baby") was observed. In 56 of them (60.9%) spontaneous delivery took place, in 4 (4.3%) women birth with vacuum extractor was performed, and in 32 (34.8%) caesarean section was done. In 24 of 116 women (20.7%) the pregnancy outcome was unsuccessful. In 12 of them (10.3%) missed abortion, and in 7 women (6%) spontaneous abortion was observed. 2 patients (1.7%) had caesarean section (in 24th and in 29th week of gestation) because of preeclampsia. One birth (0.9%) was premature because of the cervical incompetency. CONCLUSIONS: The pregnancy outcome in women after ovulation induction is frequently (20.7%) unsuccessful. The delivery in patients after ovulation induction frequently (34.8%) takes place with caesarean section.

Adult↗
PubMed2000

[Continuous amnioinfusion in premature rupture of membranes].

Results of premature rupture of membranes treatment including administration of continuous amnioinfusion procedure using amniotal catheter in 18 pregnancies between 23 and 28 weeks of gestation are presented in the study. Only a few early treatment complications and high rate of clinical success in the aspect of fetal surveillance were found. Clinical evidence of intra-amniotal infection after 2-6 weeks of therapy had become cesarean section cause in most cases of the study group. Authors have observed 17 live birth (one case of placental ablation excluded) with birth weight in the range of 950-2210 g (1540 +/- 230 g) with Apgar score 5-7. In the early neonatal period 7 cases of intensive care and 2 neonatal deaths were found.

Adult↗
PubMed2000

[Usefulness of the pulse oximetry in diagnosis of fetal distress during labor].

We report the computer control system of simultaneous monitoring of cardiotocography and pulse oximetry during labour. Five of twenty five patients have abnormal CTG results with oxygen saturation over 30%. In the three subjects severe late decelerations were related with decrease of saturation to 20%. Mean SaO2 measurements ranged from 62% at the early stage of labour to 45% in the second stage. We conclude that fetal pulse oximetry plays important complementary role among methods of intrapartum monitoring and it will be used in every case with suspicious or pathological CTGm.

Cardiotocography↗
PubMed1996

[Pregnancy induced changes in lipid-lipoprotein serum profile in women and newborn birth weight].

The pregnancy is associated with hyperlipoproteinemia including an increased level of total cholesterol, LDL-cholesterol, HDL2 and HDL3-cholesterol and triglycerides. The mechanism of pregnancy associated hyperlipoproteinemia remain unclear. The aim of the study was to estimate the relationship between the newborn body mass at delivery and changed by pregnancy lipid-lipoprotein blood profile in women. Studies were carried out in the cases of 67 women. Blood samples were studied at 25 week of pregnancy, during the labor, and at 5th day after delivery. No influence of the pregnancy-changed lipid-lipoprotein pattern of the mothers on the body mass of newborns was found in any of the investigated period.

Adult↗
PubMed1996

[The type of material primary hyperlipoproteinemia and newborn birth weight].

Twenty four cases of hyperlipoproteinemia were reported in the investigated group of 67 mother, which delivered behind 38 and 41 week of pregnancy newborns above 2500 g body mass. They were characterized as IIa and IV types according to the WHO classification. Fifteen mothers had HLP of IV type. The average delivery body mass of newborns of these mothers was 3550 g. Nine mothers had HLP of IIa type and these mothers delivered the lightest newborns, average delivery body mass was 3117 g while the average of with normolipidemia mothers was 3238 g. The chi 2 test indicated that the delivery body mass of the newborns is related to the type of hyperlipoproteinemia of mother (p < 0.05).

Adult↗
PubMed1996

[Lipid-lipoprotein serum profile of the newborn and its birth weight].

The sixty-seven newborns were investigated. The umbilical cord blood samples were used to determine following indices: total cholesterol, LDL, HDL2, HDL3-cholesterol, total phospholipids, LDL, HDL-phospholipids, triglycerides and apolipoprotein B. The chi 2 test indicated correlations between increased levels of triglycerides, phospholipids LDL and cholesterol HDL2 and decreased level of cholesterol LDL in the group of newborns with the lowest delivery body mass.

Birth Weight↗
PubMed1995

The total free radical trapping ability of blood plasma in eclampsia.

The interaction between various antioxidants may be important in protecting against oxygen toxicity. We studied the total radical trapping capacity of the antioxidants in plasma (TRAP) and compared the TRAP-level in the patients with eclampsia with that in normal pregnant women. The measured and calculated TRAP-level was higher in the control group than in the group with eclampsia. The uric acid, vitamins E and C and sulfide concentrations were lower in the group of women with eclampsia compared with the controls. The central conclusion from this work is that for patients with eclampsia, the plasma concentrations of the essential nutrients: vitamin E, vitamin C, and cysteinerich protein are too low for optimal antioxidant systems activities.

Adult↗
PubMed1995

[Mineral components of the human placenta, birth weight and infant head circumference].

Levels of mineral elements (F, Na, Mg, Al, S, Cl, K, Ca, V, Cr, Mn, Fe, Co, Cu, Zn, Se, Br, Rb, Mo, Cd, J, Ba, Hg and Pb), the role of which is well known and documented, were studied in 365 placentas. The significant negative correlations were ascertained between the content of Pb, Cd, F, Hg and the birth weight; the positive correlations were ascertained between some minerals (Mg, Ca, Co, Cu, Zn, Se) that are indispensable for the proper organism functioning and the fetus development.

Birth Weight↗
PubMed1995

[Retinoids--drugs with a strong teratogenic side effect].

The derivatives of the vitamin A--retinoids, are very precious drugs used in dermatology. Forever, they are very strong teratogens and their applications in case of women before the menopause may cause serious deformations of the fetus. So we presented the recommendations so as to applications of the retinoids in such women.

Abnormalities, Drug-Induced↗
PubMed1995

[Decreased activity of oxidoreductases in erythrocytes and blood platelets from venous and umbilical blood of women with pregnancy-induced hypertension].

Thirty two pregnancies with pregnancy-induced hypertension (PIH) and twenty seven control normal pregnancies were analysed with regard to maternal and fetal blood enzymatic antioxidants. In PIH maternal erythrocyte, platelet and serum blood and in umbilical cord blood levels of lipid peroxides were higher than in normal pregnancy. Also the activities of platelet and erythrocyte superoxide dismutase and glutathione peroxidase were lower in PIH women. The concentration of lipid peroxides was higher, and the activity of glutathione peroxidase were lower in umbilical cord elements of women with PIH, than corresponding values of women with normal pregnancy. We suggest that disturbances in antioxidant enzymatic system are involved in the pathogenesis of maternal PIH, and it may also have effects on the function of antioxidant status of the fetus.

Adult↗
PubMed1994

[Usefulness of determining tumor markers CEA, CA125 and CA72-4 in blood serum of patients with ovarian carcinoma].

Serum levels of 3 markers: CEA, CA125 and CA72-4 have been determined in 58 patients aged from 15-60 years with histologically diagnosed ovarian cancer. Serum CEA was determined by radioimmunoassay using kits POLATOM (Poland), CA72-4 was determined using kits CIS BIOINTERNATIONAL (France) and CA125 was determined by enzyme immunoassay using kits Hoffmann-la-Roche (Wien-Austria). We have observed the growth of sensitivity and specificity of serum levels: CA125 and CA72-4 if we have referred to the simultaneous elevation of CA125 and CA72-4 markers. We have observed that CA125 and CA72-4 elevated levels were proceeded clinical recurrent of the disease from 2 to 6 months.

Adolescent↗
PubMed1994

[Bile acids from blood serum of women during normal pregnancy].

Bile acid concentrations were measured enzymatically in study of women through normal pregnancy. Mean serum bile acid levels increased significantly, from 5.3 (SD 0.9) mumol/l at 16 weeks to 7.2 (SD 1.0) mumol/l at term. Serum bile acid concentrations were greater of older women, than of younger women.

Adult↗
PubMed1994

[Zinc levels in semen of men from childless marriages].

Zinc concentration in human semen was studied on the material of 106 male patients aged 20-35, from childless marriages. Full microscopic examination was performed including number of spermatozoons, mobility, fluxing time, pH, morphological composition, number of leucocytes. Zinc level was measured using spectrophotometric analysis. Trial of relation estimation between zinc concentration and number of live spermatozoons and pH of the semen was taken out. Any significant differences between zinc concentration in the semen from normospermic and oligospermic males were found. There was proved, that semen pH increase was correlated to zinc concentration decrement in the semen fluid.

Adult↗
PubMed1994

Serum potassium levels during pregnancy.

In our study of potassium levels in normal pregnant women the mean serum potassium concentration was 5.65 (0.76) (SD) mmol/l. This level decreased with maternal age and parity and increased progressively with gestational age. The value recorded in the first trimester was 4.25 mmol/l, which increased to 5.83 mmol/l in the second trimester and to 5.95 mmol/l in the third trimester. Apart from other factors that affect serum potassium levels during pregnancy, the social status of the pregnant women was also found to influence the values, rising from 4.97 mmol/l in the case of poor women to 6.03 mmol/l in the case of civil servants. The nutritional implications of this study with respect to proper fetal development is discussed.

Adolescent↗