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Biomedical subjects

J V Robinson

Publications and source records attributed to J V Robinson.

12 recordsLinked to original sources
PubMed1992

Efficacy of Bacillus thuringiensis var. israelensis against larvae of the southern buffalo gnat, Cnephia pecuarum (Diptera: Simuliidae), and the influence of water temperature.

Susceptibility of southern buffalo gnat larvae to Bacillus thuringiensis var. israelensis (B.t.i.) was studied during 1986-88. Tests were conducted using Vectobac 12AS in a mini-gutter aquatic bioassay system. Mini-gutter tests using a 4.5 ppm B.t.i. concentration and a 10 min exposure period confirmed a positive correlation between water temperature and B.t.i. effectiveness. Significantly lower larval mortality occurred as water temperature decreased below 9 degrees C, indicating that proper timing of B.t.i. application is essential to maximize larval control. Even with this temperature limitation, larval control using B.t.i. should provide an economically effective means of preventing outbreaks of the southern buffalo gnat.

Animals↗
PubMed1991

Structural and antigenic polymorphism of the 35- to 48-kilodalton merozoite surface antigen (MSA-2) of the malaria parasite Plasmodium falciparum.

Merozoite surface antigen MSA-2 of the human parasite Plasmodium falciparum is being considered for the development of a malaria vaccine. The antigen is polymorphic, and specific monoclonal antibodies differentiate five serological variants of MSA-2 among 25 parasite isolates. The variants are grouped into two major serogroups, A and B. Genes encoding two different variants from serogroup A have been sequenced, and their DNA together with deduced amino acid sequences were compared with sequences encoded by other alleles. The comparison shows that the serological classification reflects differences in DNA sequences and deduced primary structure of MSA-2 variants and serogroups. Thus, the overall homologies of DNA and amino acid sequences are over 95% among variants in the same serogroup. In contrast, similarities between the group A variants and a group B variant are only 70 and 64% for DNA and amino acid sequences, respectively. We propose that the MSA-2 protein is encoded by two highly divergent groups of alleles, with limited additional polymorphism displayed within each group.

Amino Acid Sequence↗
PubMed1978

The dilemma of the second surgeon.

The dilemma of the second surgeon is created when a patient is seen who has received advice and/or treatment by a colleague in the same specialty. The problem is compounded when conflicting opinions as to diagnosis, treatment, and results occur. This is discussed in the context of providing optimal care, maintaining effective communication, and avoiding the obvious pitfalls.

Diagnosis↗
PubMed1977

Finding the missing information in cancer statistics.

The current cancer literature is imprecise and confusing. This hampers the ability to draw meaningful conclusions regarding diagnosis and treatment. It is suggested that all future reporting of statistics contain the following features: (1) discussion of case selection criteria; (2) use of TNM system for case classification; (3) listing of minimal treatment details; (4) explanation for length of follow-up used; (5) standardized terms for evaluation (relating these to individual TNM classification); and (6) listing of all failures by standardized terms. It is proposed that editors of journals and organizers of meetings reject all papers that do not meet these criteria.

Bibliographies as Topic↗
PubMed1975

A comparison of the biochemical activities of Bacteroides corrodens and Eikenella corrodens with those of certain other gramnegative bacteria.

Tests carried out on strictly anaerobic and facultatively anaerobic strains of "corrodens" bacteria, showed that although these organisms are relatively inactive biochemically, differentiation can be made on the basis of tests that demonstrate reduction of nitrite, hydrolysis of urea and 1-naphthyl acetate, decarboxylation of lysine and ornithine, and sensitivity to certain selective agents included in culture medium. Plasma was found to be superior to serum in supporting the growth of all "corrodens" bacteria, and a combination of heated and unheated blood added to a nutrient base was shown to yield good growth. Comparative studies are reported with various species of Bacteroides, Haemophilus, Bordetella and related genera.

Amino Acids↗
PubMed1975

Some observations on the effects produced in white mice following the injection of certain suspensions of corroding bacilli.

Strictly anaerobic and facultatively anaerobic strains of "corroding bacilli" failed to produce any pathological symptoms when injected into white mice and no viable organisms could be recovered after 7 days. However, when these same strains were coupled with certain other living bacteria or certain sterile bacterial extracts, lesions developed from which corroding bacilli could be isolated even after 21 days.

Animals↗
PubMedDate not supplied

Facial nerve repair in cerebellopontine angle surgery.

Facial nerve continuity was restored during cerebellopontine angle tumor removal in nine cases. The distal facial nerve was rerouted from the stylomastoid foramen into the cerebellopontine angle. Direct suture was accomplished in seven cases while two required interposition of a greater auricular nerve graft. There was excellent return of facial function in eight of the nine cases. Overall results are superior to nerve substitution techniques. The facial nerve should be inspected for continuity following tumor removal. If one is not certain the nerve is intact, the proximal facial stump should be identified at the brain stem and facial nerve continuity reestablished. A nerve substitution procedure should be resorted to a later time only when the proximal facial stump is not identifiable.

Adult↗