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Biomedical subjects

J W Patterson

Publications and source records attributed to J W Patterson.

At least 127 records · Page 7Linked to original sources

Pterygium inversum unguis-like changes in scleroderma. Report of four cases.

During an 18-month period, four patients with scleroderma were found to have nail findings suggestive or pterygium inversum unguis, a recently described condition. In the same time period, two other examples of the disorder were seen. Pterygium inversum unguis-like change may represent an additional nail sign in scleroderma. There are possible mechanisms for its development in patients with Raynaud's phenomenon, connective tissue diseases, or peripheral vascular disease.

Adult↗

The effect of tonicity on lens volume.

Rat lenses incubated in hypotonic medium adapted to the medium by first undergoing osmotic swelling and then returning after 1 to 2 days to their originial volume. Two processes--osmotic swelling and volume regulation--appear to be working simultaneously. The former is indicated by a decrease in the concentration of cell potassium to the expected level and the latter by a limitation of lens volume associated with a decrease in the potassium content of the lens. These findings are consistent with those observed in other types of cells and may be of significance in understanding the etiology of cataracts.

Animals↗

A comparison of Rhodnius prolixus, Triatoma infestans and Panstrongylus megistus in the xenodiagnosis of a chronic Trypanosoma (schizotrypanum) cruzi infection in a rhesus monkey (Macaca mullatta).

Fifth instar Rhodnius prolixus, Triatoma infestans and Panstrongylus megistus were fed on a rhesus monkey (Macaca mullatta) with a chronic infection of Peru strain Trypanosoma cruzi and examined 30 days later for the presence of trypanosomes in the rectum. No correlation could be demonstrated between either blood meal size or sex and the subsequent development of a rectal infection with T. cruzi. As T. infestans and P. megistus were more highly infected than R. prolixus in terms of both percentage infected and degree of infection, the two former species can be regarded as more suitable for the xenodiagnosis of this particular strain of T. cruzi in M. Mullatta.

Animals↗