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Biomedical subjects

J Waldschmidt

Publications and source records attributed to J Waldschmidt.

At least 73 records · Page 4Linked to original sources
PubMed1987

Therapeutic results in cryptorchidism after combination therapy with LH-RH nasal spray and hCG.

Seventy-two boys with 81 cryptorchid testes were treated with combined LH-RH nasal spray and hCG in the period between 1983 and 1985. Cryptocur (LH-RH) was applied as nasal spray at a dose of 1.2 mg daily over a period of 14 days. In all of the patients, hCG treatment was carried out subsequently according to the WHO guidelines with five intramuscular injections at 2-day intervals. Primary treatment results considerably improved using the regimen. The rate of complete descent was 86.4% at the end of therapy and later dropped to 70.6% after 2 years follow-up. These results support the experience of Hadziselimovic et al. with this combined treatment.

Administration, Intranasal↗
PubMed1987

[Acute abdomen in immunoreaction mediated diseases].

Assessment of the acute abdomen as a real or simulated complication in immunovasculitis is extremely difficult. Despite modern laboratory and imaging procedures, the number of false diagnoses is considerable, and a superfluous, falsely indicated emergency laparotomy can be just as fatal as the failure to perform a necessary surgical intervention. It is important to do a careful follow-up, including sonography and possibly laparoscopy, and to bear in mind the experience of H. Bailey with PSH that complications are often suspected but only seldom found.

Abdomen, Acute↗
PubMed1987

[Disease picture of primary chronic intestinal pseudo-obstruction in childhood].

Primary CIPSO involves ileus symptoms without mechanical occlusion; these are caused by absence or ineffectiveness of peristalsis despite normal intestinal wall structure. The neonatal and adult types are differentiated. Ileus is progressive in the neonatal clinical pictures of CIPSO (neonatal CIPSO, MMIHS, congenital short-bowel syndrome) and chronic in the adult type, where it is also ultimately fatal, however. The problems of diagnosis and therapy are discussed and demonstrated in 5 children with primary CIPSO.

Adult↗
PubMed1987

[Diagnosis and differential diagnosis of congenital fistulas and cysts of the neck].

Maldevelopment of the embryonal branchial arches may result in widely different cervical midline and ear anomalies. It should generally not be difficult and clinically feasible to diagnose them and differentiate them against other diseases if one is conversant with the associated special embryological and anatomical features. Nevertheless, false diagnoses are still frequent. The rate of diagnostic errors is almost 20% in our own 318 child patients with swellings in the cervical midline. Hence, it is easy to understand why there is a demand for widening the scope of preoperative diagnosis. Sonography offers a highly effective imaging examination technique. Additional information can also be gained occasionally via CT and angiography. We can, however, usually omit punctures and x-ray imaging of fistulas.

Child↗
PubMed1985

[Abnormalities of the stomach].

Malformations of the stomach are rare, their complications can be very dangerous in infancy. Clinical picture and diagnosis are discussed using 5 own cases (one 2-years-old girl with membraneous atresia, one 3-day-old boy with pylorus atresia, one 2-years-old boy with bleeding diverticulum of the stomach and a newborn with tubular hypoplasia (i.e. microgastria)). The treatment of these malformations is always surgical. Only cases of membraneous stenosis of the stomach may be treated endoscopically.

Diagnosis, Differential↗
PubMed1985

[Disease picture of intra-abdominal hernias in childhood].

Through the demonstration of 3 cases (6-year-old-girl with right mesenterico-parietal hernia; 2 year-old-boy with a transverso-mesocolic hernia; 10-months-old-boy with a hernia in the mesenterium of a M.D.) we discuss the problems of intraabdominal hernia. The evaluation of the disease can take many forms. Only one third of the children remains without symptoms; the other third has a chronic evaluation and the last third an acute abdomen. Once diagnosed internal hernia must soon be operated.

Adolescent↗
PubMed1983

[Technical procedure in the use of lyophilized dura for closure of extensive abdominal wall defects].

In the Department of Pediatric Surgery in the Steglitz Hospital of Berlin Free University, major defects in the thoracic and abdominal wall and other sites were treated in 122 children by implantation of lyophilised dura. Surgery was performed 49 times at the abdominal wall, 26 times at the diaphragm, 14 times at the thoracic wall, and 33 times in various other regions. Lyophilised dura, after it has been desantigenised and sterilised, is very versatile in application. However, it is necessary to avoid any area of contact with the lumen of the digestive tract, the tracheo-bronchial system and the body surface. If the implanted dura can be covered with endogenous soft parts and skin, complete incorporation is achieved with the formation of a solid cicatricial plate which provides satisfactory stabilisation of the wall even in extensive defects. Another essential prerequisite is safe anchoring of the dura implants, which can always be achieved if an appropriate suturing technique is employed.

Abdominal Muscles↗
PubMed1983

[Omento-porto-duodeno-pexy in the treatment of bile-duct atresia and hypoplasia in infants].

From 1975 to 1982, central lymph drainage was performed in our hospital, on 12 infants with atresia of the intrahepatic bile ducts. The greater omentum was used for the drainage. It was mobilized and attached to the incised hilar lymph nodes and lymphatic vessels of the hepatic-duodenal ligament and to the decapsulated duodenum. In two children, this method was combined with Kasai's operation. These two children developed cirrhosis of the liver. Only one of the other 10 children, who underwent our own procedure, has developed cirrhosis so far. The remaining 9 children show no signs of liver damage.

Age Factors↗
PubMed1983

[Intra-abdominal ligament remnants of the vitelline duct and vessels].

Intraabdominal bands of the vitelline vessels and vitelline duct are discovered as a congenital disturbance any time in life. In more than 75% they cause an acute abdominal disease. In this paper we discuss the cause and the clinical picture in 19 children seen in our department together with 83 cases from the literature. In 70% of the cases we find remnants of the right and left vitelline artery, in a third remnants of the vitelline vein and vitelline duct. The characteristic course is the acute strangulation of the intestine with gangrene of the bowel and endotoxine shock. The best treatment in every case is the operation as soon as possible.

Abdomen, Acute↗
PubMed1980

[Diagnosis and treatment of congenital cysts and fistulae of the neck].

The diagnosis and operative treatment of congenital cervical fistulae and cysts are in many cases difficult, especially abnormalities of the first branchial cleft and of the sinus cervicalis. In our hospital 90 congenital cervical fistulae and cysts were treated surgically between April 1972 and August 1979, excluding cysts of the thyroid gland, lymphangiomas etc. Four of these children with a median cyst and two children with fistulae of the first branchial cleft had recurrences due to partial obliteration and fibrosis of the ducts following inflammation. Other causes for recurrence were atypical locations of the fistulae and cysts. Therefore it is necessary to operate the congenital fistulae and cysts as early as possible.

Branchioma↗
PubMed1980

[Megaduodenum in the newborn (author's transl)].

Megaduodenum presents a functional obstruction which is difficult to correct surgically. Various serious complications have been reported and repeat laparotomy is frequently necessary. 6 newborns with megaduodenum are reported and a sub-total longitudinal resection of the duodenum is advocated. The remainder of the duodenal wall is reconstituted over a tube and this procedure has been used by us 4 times. 3 infants have survived. It may be possible to avoid repeat laparotomy by the method described above.

Duodenal Obstruction↗
PubMed1980

[The syndrome of the fifth postoperative day after appendicectomy (author's transl)].

41 children were subjected to re-laparotomy because of obstruction after appendectomy. The causes were entero-colitis, occlusive ileus, rupture of the bowel and suture insufficiency. In this paper we report 6 children who had none of these complications. In these 6 children a "5-day syndrome" consisted usually of a fatal outcome with severe general peritonitis without a leakage of the appendix stump. Infection caused the endogenous spread of Bacteroides, following paralytic ileus and septicaemia. Early therapy with antibiotics and eventual re-laparotomy is then necessary.

Adolescent↗
PubMed1980

[Experience in treating hepatic coma by extracorporal liver perfusion (author's transl)].

19 extracorporeal liver perfusions have been performed for treating hepatic coma in 11 patients. No improvement was found in 3 patients, improvement in 8.5 of these 8 patients recovered full consciousness. All 7 patients with pre-existent liver disease died. Of 4 patients without pre-existent liver disease, 2 were discharged and are still alive. At present, extracorporeal liver perfusion seems to be the most promising treatment for hepatic coma. It should be undertaken at Stage IV and at Stage III with increasing prothrombin time. Pre-existent liver disease should be excluded before by laparoscopy.

Adult↗
PubMed1979

[Treatment of complications of pulmonary anomalies in childhood (author's transl)].

Congenital anomalies of the lungs very often remain asymptomatic and are discovered accidentally during routine examinations. Only one-third of 24 patients with congenital pulmonary abnormalities showed acute symptoms; in a further one-third a chronic recurrent symptom complex required surgical intervention as the only possible mode of treatment. The complications arising from these anomalies varied considerably. The most serious was the "acute thorax" in newborns; in a number of cases it needed emergency thoracotomy. The various types and their symptoms are described and their treatment is reviewed.

Adolescent↗
PubMed1979

Causes of death in operated neonates with diaphragmatic defects.

The causes for the high mortality in neonates with diaphragmatic hernia are manifold. These cases have to be classified as being in the "fatal zone" of Boix-Ochoa. Analysis of our patients showed that 27 patients belonged to this group, 15 of whom died. The causes of death were hypoplasia of both lungs in 1 case and intracranial haemorrhage in 1. In 6 neonates there were additional complex cardiac malformations and in 1 other severe malformations. The foetal circulation persisted in 3 infants and a tension pneumothorax was the cause in 2, an intestinal obstruction the cause of death in 1 infant. In these 5 last-mentioned children, improvements in treatment might have possibly prevented death.

Abnormalities, Multiple↗