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Biomedical subjects

James M Hartford

Publications and source records attributed to James M Hartford.

8 recordsLinked to original sources

Surveillance venous duplex is not clinically useful after total joint arthroplasty when effective deep venous thrombosis prophylaxis is used.

The early detection of deep venous thrombosis (DVT) and treatment with systemic anticoagulation to prevent pulmonary embolism (PE) are essential in the management of patients undergoing total joint arthroplasty (TJA). However, improvements in prophylactic measures have significantly decreased the occurrence of DVT in these patients. The purpose of this study was to determine whether routine postoperative duplex surveillance for DVT remains clinically useful. The medical records of all patients undergoing total knee or total hip arthroplasty between October 1997 and January 2002 at a University Hospital and its Veterans Affairs (VA) affiliate were reviewed. The type of operation and occurrence of complications (e.g., DVT, PE, and hemorrhage) were noted. All patients were treated postoperatively with both enoxaparin 30 mg b.i.d. and bilateral lower extremity sequential compression devices (SCDs). A venous duplex scan was performed prior to discharge. Three hundred ninety-eight patients underwent 441 TJAs for 149 hips and 292 knees. The average age was 65 years (range, 23-95). Venous duplex scans were performed within 1 week (median, 4 days) of operation. Initial inpatient scans revealed acute, ipsilateral DVT in five patients (1.3%). Three patients experienced documented PE-one as an inpatient and two after hospital discharge; both outpatients had negative inhospital duplex scans. One of the 398 patients did not have a duplex scan as an inpatient and returned 6 weeks later with a popliteal DVT. Complications included one upper gastrointestinal hemorrhage, and one patient died postoperatively of unknown causes. These data demonstrate that routine postoperative venous duplex scans rarely found DVT (5 of 398 patients) after TJA when effective prophylaxis was used. Furthermore, surveillance scanning did not enable reliable prediction of PE. Therefore, we conclude that postoperative inpatient surveillance duplex scans for DVT provide very minimal benefit and that a routine screening program is not clinically useful for patients managed with effective DVT prophylaxis.

Adult↗

Biomechanical superiority of plate fixation for proximal tibial osteotomy.

Proximal tibial osteotomies require secure and durable fixation to allow early range of motion; however, biomechanical data comparing commonly used fixation methods are lacking. The current study was done to quantify the dynamic biomechanical performance of blade staple fixation and plate fixation of simulated proximal tibial osteotomies. A 15 degrees proximal tibial osteotomy was done on each of 18 synthetic adult composite tibias. Blade staples were used as the means of fixation in nine tibias; plate fixation was used in the remaining nine tibias. The specimens were stressed cyclically in sinusoidal loading whose peak compression and tension loads imitate those measured during normal gait. Device performance was quantified by measuring displacement at the osteotomy site and the number of cycles to failure. Plate fixation had a greater fatigue life than staples (eight plates surviving past 200,000 cycles versus one blade staple) and showed a trend toward less displacement (0.69 mm versus 0.97 mm). Plate fixation of proximal tibial osteotomies offers better fixation and dynamic mechanical performance than blade staples.

Adult↗

Endovascular repair of external iliac artery occlusion after hip prosthesis migration.

PURPOSE: To report emergent endovascular intervention to restore lower extremity arterial patency after migration of a hip prosthesis caused thrombosis of the external iliac artery (EIA). CASE REPORT: Nine months following left hip revision arthroplasty, a 66-year-old woman presented to the Emergency Department with the complaints of an acutely painful left lower extremity for over 6 hours. Imaging showed the metallic acetabular portion of the hip prosthesis in the iliac fossa, with severe external compression of the EIA. After thrombolysis to remove clot from the EIA, an 8x60-mm self-expanding Smart stent was deployed in the left EIA from a contralateral access. The procedure was successful, and the patient was discharged. An infected wound from a compartment fasciotomy delayed revision of the hip prosthesis. Nine weeks after stenting, the patient returned with a cold, pulseless left limb; a femorofemoral bypass was constructed to restore perfusion. CONCLUSIONS: While stent placement restored flow for 9 weeks after the initial ischemic event, the recurrent thrombosis could have been prevented by earlier revision of the migrated prosthesis.

Aged↗

Intraoperative frozen section analysis in revision total joint arthroplasty.

A prospective study of the sensitivity, specificity, and predictive values for frozen sections against cultures obtained at the time of revision total joint replacement was done. One hundred twenty-one revision total joint replacements were done in 92 men and 29 women. A positive frozen section with more than 10 polymorphonuclear leukocytes per high power field was compared with the intraoperative cultures. Twenty-one patients who had revision surgery had greater than 10 polymorphonuclear leukocytes per high power field. Of these, 14 patients had positive cultures. The remaining 100 patients had less than 10 polymorphonuclear leukocytes per high power field, but seven had positive cultures. Statistical analysis of frozen sections for all total joint arthroplasties revealed a 67% sensitivity, 93% specificity, 67% positive predictive value, and 93% negative predictive value. Analysis of frozen sections for total hip arthroplasties revealed a 45% sensitivity, 92% specificity, 55% positive predictive value, and 88% negative predictive value. Analysis for total knee arthroplasties revealed 100% sensitivity, 96% specificity, 82% positive predictive value, and 100% negative predictive value. Comparisons of sensitivity, positive predictive value, and negative predictive value between total knee arthroplasty and total hip arthroplasty were significant. The results indicate that the use of intraoperative frozen section analysis with greater than 10 polymorphonuclear leukocytes per high power field as an indication of infection lacks the positive predictive value and sensitivity for accurate determination of prosthetic infection at the time of revision total hip arthroplasty. Frozen sections have an acceptable sensitivity and positive predictive value in total knee arthroplasty. The results of the current study show the limitation of using frozen sections as a diagnostic test for infection in revision total hip arthroplasty.

Adult↗

Press-fit metal-backed rotating patella: seven- to 14-year followup.

A consecutive series of 80 patients with 110 press-fit metal-backed rotating platform patella resurfacing surgeries were reviewed at an average of 107 months followup (range, 84-167 months). Twenty-eight patients died before followup. Fifty-two patients (70 patellae) were available for clinical and radiographic followups. One patella was revised for failure of the patella component. Four patellae were revised along with revision of the knee replacement. One patella realignment procedure was done for recurrent subluxation of the patella. There were no patellar dislocations in this series, no patella fractures, and no disruption of the quadriceps tendon or infrapatellar ligament. Six patellae had subluxation seen on postoperative radiographs. The incidence of patellar tilt greater than 5 degrees was 13%. No patellae were considered radiographically loose. The incidence of radiolucencies was 37%. Subsidence of the component superiorly was identified in 39% of the patellae, and inferiorly in 36% of the patellae. Of the 49 patients (67 knees) returning for followup, 70% of the knees were rated as excellent, 10% were rated good, 15% were rated fair, and 5% were rated poor. Press-fit metal-backed patella provided good component durability with only one revision because of component failure. Radiographic analyses showed a high incidence of subsidence associated with good clinical results.

Aged↗

Athletic activity after total joint replacement.

Total hip and knee replacement surgery is a successful treatment for the arthritic hip and knee ensuring proven pain relief and return of function. Younger, more active patients who have greater expectations and higher demands are receiving hip and knee replacements. With current surgical techniques and implant designs, athletic participation should be limited to low impact, low demand, and low duration activity. Future advancesin bearing surfaces may allow for higher demand activities.

Age Factors↗

Intertrochanteric osteotomy using a dynamic hip screw for femoral neck nonunion.

The dynamic hip screw, which is routinely used for intertrochanteric hip fractures, also provides a technically simple means of fixation for intertrochanteric valgus osteotomies in the treatment of femoral neck nonunions. Eight patients underwent intertrochanteric valgus osteotomy for femoral neck nonunion using a dynamic hip screw for fixation. One patient died 4 months postoperatively of causes unrelated to the procedure. The remaining 7 patients were followed for an average of 24 months postoperatively. The nonunion healed in all 7 cases. The average angle of the fracture plane decreased from 68 degrees to 41 degrees. All the hip fractures were classified as Pauwels type III preoperatively and Pauwels type II postoperatively. The average Harris Hip Score increased from 24 to 73. On radiographic review, no cases of osteonecrosis were identified postoperatively.

Bone Screws↗