Biomedical subjects

John P Barber

Publications and source records attributed to John P Barber.

2 recordsLinked to original sources

PubMed2006

Single-molecule detection sensitivity using planar integrated optics on a chip.

We present a fully planar integrated optical approach to single-molecule detection based on microfabricated planar networks of intersecting solid and liquid-core waveguides. We study fluorescence from dye molecules in liquid-core antiresonant reflecting optical waveguides, and demonstrate subpicoliter excitation volumes, parallel excitation through multiple pump waveguides, and single-molecule detection sensitivity. Integrated silicon photonics combined with single-molecule detection in solution create a compact, robust, and sensitive platform that has applications in numerous fields ranging from atomic physics to the life sciences.

Biopolymers↗

PubMed2004

Fabrication and analysis of a low-loss in-fiber active polymer waveguide.

We present a method for fabricating an in-fiber electro-optic polymer waveguide within a D-shaped optical fiber. A combined process of selective chemical etching and spin coating creates a 2-cm in-fiber poly(methyl methacrylate)-DR1 dye polymer waveguide section with an overall insertion loss of micro 1.6 dB at 1550 nm. Numerical simulations show that, for in-fiber polymer waveguides to have low loss, the polymer layer's thickness must be kept below a certain value so that it will not support slab waveguide modes. Long transition regions between the unetched fiber and the polymer waveguide section also reduce loss. We analyze the efficiency of an in-fiber polymer waveguide by simulating its theoretical performance as an electro-optic modulator.

Journal Article↗