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Biomedical subjects

K Amon

Publications and source records attributed to K Amon.

At least 19 recordsLinked to original sources
PubMed1990

[Dislocation-fracture of the cunei-navicular joint line. Clinical aspects, pathomechanism and therapeutic concept in a very rare foot injury].

Fracture dislocations of the cunei-navicular joints are a very rare type of intertarsal dislocation and most people are probably unfamiliar with this entity. Clinical, radiological and pathological aspects allow discrimination of such injuries from the dislocations in Lisfranc's and Chopart's articulation. We have seen one patient who was found to have a crush fracture of the cuneiforme mediale on one side and a fracture disruption with dorsal dislocation of the first and second metatarsals and of the medial and intermediate cuneiform bones on the other. According to the principles of treatment for other tarsal injuries, we carried out open reduction with joint debridement, reconstruction of ligaments and internal stabilization with transfixation screws.

Bone Screws↗
PubMed1990

[Force couple splint in unstable dislocation fracture of the interphalangeal joint].

A well-documented percutaneous method in the treatment of fracture dislocations of the PIP joint, the force couple splint technique according to Agee produces good functional results in these rare injuries. This paper presents our own modification with mass-produced preconstructed couple splints, which can be combined precisely with the elements of a mini-external fixation system.

Finger Injuries↗
PubMed1989

[Dynamic transfixation in unstable dislocation fracture of the proximal interphalangeal joint].

Unstable fracture dislocations of the PIP-joint are difficult to manage, because the primary joint destruction and the necessity of immobilisation often result in joint stiffness and the loss of immobilisation may promote chronic subluxation. In the case described in the article we treated the unstable fracture dislocation with a dynamic transfixation with a "force couple splint" following the open reconstruction and internal fixation of the destroyed joint. The application of this dynamic transfixation allowed early active mobility exercising of the PIP-joint during bone healing and produced an excellent result.

Adolescent↗
PubMed1989

[Dislocations of the talus joints].

With the exception of fracture dislocations following fractures of the ankle joint and talus, dislocations in the talus are very infrequent injuries. They pose a lot of management problems: soft-tissue damage in open and closed dislocations, imperfect reduction caused by osteochondral fragments, recurrent instability, and aseptic necrosis of the talus, which is greatly feared. Anatomical and prognostic criteria are included in a classification of mono-, bi- and triarticular dislocations of the talus. Based on six of our own cases treated in the last 12 months, we report the mechanisms of injury, management, and early results. In accordance with the results in the literature in the last few years, reconstruction of ligament damage and joint debridement were carried out in four cases and the results described. One case of open total dislocation of the talus is presented, which was complicated by a fracture of the calcaneus without traumatic avascular necrosis.

Ankle Injuries↗
PubMed1989

[Functional and morphological changes in the pharynx in achalasia and diffuse esophageal spasm].

Since the pharynx and the esophagus are a functional unit, functional radiodiagnosis has to be directed at pharyngo-esophageal interaction. Among our collective of 73 patients suffering from achalasia or diffuse esophageal spasm, we were able to recognize a substantially increased incidence of morphological or functional pharyngeal disorders by means of cineradiography. The functional alterations in particular were often not revealed by conventional fluoroscopy. High-speed cineradiography, with its high temporal and spatial resolution, turned out to be a valuable tool in analysis of the origin of pharyngeal dysphagia. Manometry correlated very well with the radiologic findings in tubular esophagus, but proved unreliable in the detection of alterations of the upper esophageal sphincter region, because of problems inherent in the method. Furthermore, membranous stenosis (webs), lateral or dorsal diverticula, and asymmetry of the pharynx were observed strikingly often.

Adult↗
PubMed1984

[Treatment of vulvovaginitis in children and adolescents with metronidazole].

Vulvovaginitis is the most observed genital disease in children and adolescents and dependent from different etiologic factors. Bacteriogenic non specific infections were the most frequent cause in 275 girls. Bacteria were evident in 77.5 per cent, monilia, in 12.7 per cent and trichomonas vaginalis in 3.3 per cent. 143 cases were treated with metronidazole. All patients with trichomoniasis vaginitis became free of trichomonads. The cure rate of the anaerobic infections was 73.1 per cent. No side effects were observed.

Adolescent↗
PubMed1984

[Problems of contraception in teenage girls].

930 female teenagers of 17 years were questioned to their knowledge of contraceptive methods and its use. Nearly 63,6% of the female teenagers with experiences of cohabitation practised no contraception. There is the demand of an increasing attention of contraception under the frame of sexual education of the youth; it's the main point.

Adolescent↗
PubMed1983

[Pharmacokinetics of metronidazole during perioperative short-term prophylaxis in cesarean section].

Placental transfer and elimination of metronidazole and its main metabolites, 1-(2-hydroxyethyl-)2-hydroxymethyl-5-nitroimidazole (metabolite I) and 2-methyl-5-nitroimidazole-1-acetic acid (metabolite II) were studied in newborn infants and compared with maternal data obtained in 8 high-risk parturients who were subjected to Caesarian section after intravenous infusion of 500 mg metronidazole. Unchanged metronidazole is rapidly transferred across the placental membranes. Its concentrations were the same in maternal venous blood and in both umbilical vessels at delivery. The concentrations of metabolite I were lower in the umbilical vein and artery than in the mother in the first hour after infusion. The elimination half-lives of metronidazole and metabolite I were markedly prolonged in the newborn infants in comparison with the maternal values. No adverse effects were observed in infants or mothers.

Bacteroides Infections↗
PubMed1983

Disposition kinetics of metronidazole in children.

The pharmacokinetics of metronidazole was studied in 20 paediatric patients aged 6 weeks and 4 to 14 years, who had trichomonal vaginitis or an anaerobic bacterial infection. The dosage of metronidazole was about 10 or 20 mg/kg b.i.d. orally. The serum concentrations found in children and the corresponding calculated kinetic parameters were similar to those in adults after intake of an equal, weight-related dose. Metronidazole shows rapid diffusion into the saliva with a concentration ratio of about 1.0. This can provide the basis for an efficient non-invasive method of drug monitoring.

Adolescent↗