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Biomedical subjects

K G Gupta

Publications and source records attributed to K G Gupta.

At least 55 records · Page 3Linked to original sources

Effect of substrates on acetoin production by Torulopsis colliculosa and Enterobacter species.

Under optimal conditions, Torulopsis colliculosa NRRL 172 and Enterobacter B-87 (ATCC 27613) produced 50 to 500 mg of acetoin per g of substrate. Whereas cane molasses, gur, glucose, and sucrose were suitable substrates for acetoin production, lactose and mannitol supported very good growth but yielded little or no acetoin. Production of acetoin increased with increases in the concentration of glucose, yeast extract, and peptone. Combination of substrates and intermittent feeding of substrate failed to increase the yields.

Acetoin↗

Presence of antisperm antibodies in fertile and infertile persons.

The sera of 70 infertile and 30 fertile couples were tested for the presence of sperm agglutinins with Kibrick's macroagglutination technique and Boyden's haemagglutination test. 15.7% of the couples studied showed the presence of sperm agglutinins (by Kibrick's method) of which 5.7% were from males and 10.0% were from females. By the haemagglutination test, 13% of the couples studied were found to possess sperm agglutinins, of which 3% were from males and 10% were from females. 30 fertile men and women studied for sperm agglutinins were found to be negative by both methods. It was also observed that these two tests detected different types of sperm agglutinins. The cervical mucus samples from 45 females (15 fertile and 30 infertile) were tested for sperm agglutinins with a mucus penetration test. 23.1, 16.5, and 57.4% of the samples from infertile females, showed 0-degree, 1-degree and 2-degree penetration respectively. In case of samples from fertile females, 6.6, 13.2 and 79.2% showed 0-degree, 1-degree and 2-degree penetration respectively. Addition of serum from infertile females to cervical mucus from the infertile female increased the 0-degree penetration percent cases to 50%, as compared with 23.1 when only cervical mucus was used. Addition of serum from fertile females, or horse serum or pure albumin or globulins did not increase the 0-degree penetration cases.

Agglutinins↗

Antibacterial activity of some newly synthesized azaphenanthrene and diazachrysene compounds.

Four newly synthesized azaphenanthrene compounds viz., 7,8,9,10-Tetrahydro-7-oxo-2-methoxy-benzo(c) phenathridine; 7,8,9,10-Tetrahydro -7-oxo-benzo(c) phenanthridine-2-[1-6-methoxy-1-naphthylimino)-methyl]cyclohexane-1,3-dione and 2-[1-(1-naphthyli; mino)-methyl]cyclohexane-1,3 dione and two diazachrysene compounds viz., 1,5-Diazachrysene and 2,5-Diazachrysese were screened for their antibacterial potency against a large number of bacterial strains. The antibacterial activity which to a varying degree was shown to be related to the aza, methoxy and keto groups, in the case of the Azaphenanthrene compounds, however, it was related to the position of the nitrogen atom in the ring in the case of Diazachrysene compounds.

Anti-Bacterial Agents↗