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Biomedical subjects

K H Hübener

Publications and source records attributed to K H Hübener.

17 recordsLinked to original sources
PubMed1979

[Computer tomographic diagnosis of abscesses (author's transl)].

The computer tomographic diagnosis of an abscess must be related to the clinical condition of a patient. In the presence of pyaemia or following an operation, with high fever, tenderness on palpation, leucocytosis and rapid development of the illness, an abscess may be suspected. The computer tomographic findings depend on the stage of the development of the abscess. Early on there is the finding of a cellular tumour with high attenuation values; after a few days, with leucocyte degeneration, there is a significant reduction in the attenuation value to that of serus fluid, or even less. Later, when organisation takes place, the development of connective tissue causes a marked increase in attenuation values which correspond with those of solid tissues. If the abscess becomes encapsulated, or if there is caseation in a tuberculous lesion, a cyst may be imitated with, again, a reduction in attenuation values. The usefulness of contrast examinations is discussed.

Abdominal Muscles↗
PubMed1979

[Computer tomographic differential diagnosis of thyroid diseases with special reference to scintigraphic cold spots (author's transl)].

A high proportion of carcinomas of the thyroid produce scintigraphic cold spots, this finding therefore requires further investigation in order to prevent unnecessary thyroidectomies. In order to clarify the value of computer tomography in thyroid disease, 70 patients with scintigraphic cold spots, or equivocal thyroid scans, were submitted to computer tomography of the neck. The findings in the majority of these cases have been correlated with histological results.

Diagnosis, Differential↗
PubMed1979

[Computer tomographic densitometry of human blood. The effect of absorption by parenchymatous organs and effusions (author's transl)].

In vitro measurements of human blood with varying haemoglobin and plasma concentrations have shown a linear relationship between haemoglobin concentrations and attenuation values. A change of haemoglobin content of 1 g/100 ml. blood produced and equivalent density change of 1.5 HU. Attenuation of normal blood is between 55 to 75 HU, that of plasma about 33 HU. Transudates with a protein concentration of less than 5 g/100 ml. show an attenuation value of less than 26 HU. It is therefore possible to indicate the presence of effusions by computer tomography. The effect of the composition of the blood on the attenuation produced by parenchymatous organs is discussed. It is concluded that attenuation values of organs is not seriously affected by even severe haematological changes.

Absorptiometry, Photon↗
PubMed1979

[Unusual CT skull findings after preventive CNS treatment of acute leukemia in children].

CT examinations of the cranium were carried out among 15 children who had previously received cranial radiation and i.th. methotrexate during leukemia management. Surprisingly, 10 of 15 patients had abnormal CT findings. Only 2 of the 10 "CT-positive" children were clinically-neurologically conspicuous. The visible CT alterations of brain structure seemed especially marked and frequent the more time had elapsed since CNS-treatment. The most striking CT pathologica were found among children up to 5 years of age, who were also conspicuous through convulsions and delayed development.

Central Nervous System↗
PubMed1979

[Comparison between conventional X-ray diagnostics and computed tomography as techniques for irradiation planning in renal carcinoma and carcinoma of the bladder (author's transl)].

In order to obtain quantitative results by means of a comparison between irradiation planning with X-ray diagnostics and planning with cross-sectional computed tomography in abdominal tumors, therapeutic programs have been established twice for the same patients, each time using one of the two techniques. Fifteen patients with renal carcinoma and 24 patients with cancer of the urinary bladder have been examined.

Humans↗
PubMed1978

[Attenuation values of normal and pathological liver tissue as a basis for computer tomographic densitometry of fatty livers (author's transl)].

Measurements of the density of normal and diffusely disease liver parenchyma show a significant difference only in the presence of fatty livers. A linear relationship between the fat content and density (g/cm3) has been demonstrated. Computer tomographic densitometry of liver tissue correlates well with physical in vitro measurements and permits measurements of fat content which are sufficiently accurate for clinical use. Other types of liver disease cannot be differentiated by densitometry.

Absorptiometry, Photon↗
PubMed1978

[Radiotherapy of testicle tumors--results and consequences (author's transl)].

A report is given on 113 patients who had been irradiated because of testicle tumors and a part of whom had been submitted to an anterior lymphadenectomy. The five-year survival rate of the seminomas of all stages was 81% (n = 61) and that of the non-seminomas of all stages was 54% (n = 52). It has to be mentioned that the group of patients with seminomas of the stages T1-2N0M0 had a five-year survival rate of 100%, and those with embryonic teratomas of all stages had a five-year survival rate of 69%. With regard to these therapy results, it is recommended to carry out the radiotherapy of testicle tumors in conformity to the individual stage. A therapy scheme is presented.

Adult↗
PubMed1978

[Conceptions for optimization in radiation therapy (author's transl)].

The discrepancy between the exact radiation planning possible nowadays and the distinctly differing real dose to the target volume is interpreted as due to the appearance of unavoidable time-dependent disturbance variables which are not quantitatively predictable. By means of the block diagram generally used in control engineering is shown the necessity of introducing a feedback mechanism with small time-lag in order to eliminate the disturbance variables. A practicable plan of such a control system for application in therapeutic radiology is outlined.

Feedback↗
PubMed1977

[Radiation therapy of renal carcinoma: investigations and results (author's transl)].

Between 1969 and 1975, 93 patients were irradiated because of renal carcinoma, most of them after surgical treatment. The 5-year survival rate was 71%; in 56% of the cases no symptom suggested metastasition or recurrence. Invasive growth into a vein was ascertained histologically in a high percentage but did not cause significant alteration of postoperative irradiation results. The evaluation reveals that megavoltage irradiation distinctly improves the prognosis after nephrectomy in comparison with sole radical operation of malignant renal tumors. In many cases radiation therapy of solitary metastases from hypernephroma may be utilized with curative intention.

Adenocarcinoma↗