[Status of immunity in bullous pemphigoid].
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Humans↗
Biomedical subjects
K Herrmann
Publications and source records attributed to K Herrmann.
[Detection of intercellularsubstance-autoantibodies after antigen-antibody-complex splitting in pemphigus foliaceus (author's transl)].
One patient suffering from pemphigus foliaceus exhibited the typical intercellular deposits of immunoglobulins in the subcorneal layers of the affected and not affected skin by direct be detected by means of several antigensubstrates. They could only be found after splitting of the antigen-antibodies-complexes. The laboratory findings exclude a more distinct deviation of the humoral and cellular immune reactivity.
Antigen-Antibody Complex↗
[Review on nonessential constituents of vegetables. III. Carrots, celery, parsnips, beets, spinach, lettuce, endives, chicory, rhubarb, and artichokes (author's transl)].
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Acids↗
[Flavonol glycosides of leaves and fruits of dill (Anethum graveolens L.). II. Phenolics of spices (author's transl)].
From the leaves of dill (Anethum graveolens L.) ten flavonol glycosides have been isolated by means of polyamide, paper and thin-layer chromatography and could be identified by the usual procedures. The two major flavonoids, quercetin 3-O-beta-D-glucuronide and isorhamnetin 3-O-beta-D-glucuronide, were obtained crystalline. The minor components were found to be the 3-glucosides, 3-galactosides and 3-rhamnoglucosides of quercetin and isorhamnetin. Two other 3-glycosides of quercetin and isorhamnetin occur with the component sugars galactose, xylose, and arabinose. Besides these there are probably other two flavonoids present in trace amounts. In addition, the fruits of dill contain kaempferol 3-glucuronide as main component thought this component is completely absent in leaves.--This is probably the first time that isorhamnetin 3-O-beta-D-glucuronide has been obtained crystalline from a plant.
Chromatography, Thin Layer↗
[Analysis of flavonoid glycosides by high pressure liquid chromatography (author's transl)].
The development of a qualitative and quantitative method of determination for glycosides of flavones, flavonols and flavanones and their aglycones by means of high pressure liquid chromatography is described. Silicagel LiChrosorb Si 60 is used as stationary phase, as well as various eluents at different temperatures. The compounds are acetylated. An extract of plum leaves serves as example of application.
Chromatography, High Pressure Liquid↗
Podocytes in the blood vessel linings of Phoronis muelleri (Phoronida, Tentaculata).
In several metasomal blood vessels of Phoronis muelleri myofilament-containing podocytes are the predominatnt cell-type. In some regions the podocytes can build a labyrinth resembling e.g. the glomerular epithelium of Enteropneusta and the axial organ of Asteroidea.
Animals↗
[Flavonol glycosides of apples (Malus silvestris Mill.). 10. Phenolics of fruits (author's transl)].
The flavonol glycosides of apple skin (Malus silvestris Mill. cv. Golden Delicious) were separated by means of cellulose column chromatography and paper chromatography, and the following compounds were obtained crystalline and identified by usual procedures: quercetin 3-O-alpha-D-galactoside, quercetin 3-O-xyloside, quercetin 3-O-alpha-L-arabinofuranoside, quercetin 3-O-rhamnoside and rutin. Quercetin 3-O-beta-D-glucoside also was identified, but could not be obtained crystallin. A comparison by TLC of 10 very different varieties of apples namely Golden Delicious, Cox Orange, Roter Berlepsch, Cortland, Ingrid Marie, Jonathan, Boskoop, Laxtons Superb, Gloster, and James Grieve demonstrated the same flavonol glycosides and thus showed no distinctions in glycosid pattern between the different varieties of these apples.
Chromatography, Paper↗
Immune function in healthy relatives of patients with malignant disease.
Immune function studies of healthy members of families with multiple lymphoreticular neoplasms were compared with those of healthy members of families with multiple cancers and families with no known history of cancer. The lymphoma family group had a significantly elevated serum level of IgM and diminished responses to the Candida albicans skin test antigen and the T-cell mitogen concanavalin A. Subjects with Epstein-Barr virus-viral capsid antigen titers greater than or equal to 160 had lower responses to mitogens.
Adolescent↗
Detection of antibodies after immune complex splitting in serum of patients with bullous pemphigoid and systemic lupus erythematosus.
No free anti-basement membrane antibodies were found in the sera of four patients with bullous pemphigoid, and no free anti-DNA antibodies in the sera of two patients with systemic lupus erythematosus. The sera treated with 3 mol/l urea and by gel chromatography to separate these antibodies from any circulating complexes, and antibodies to basement membrane were detected by immunofluorescence and to DNA by the Farr technique. The appropriate antibodies were found in all the sera, indicating that failure to detect antibodies by routine procedures may be due to binding of the antibodies to soluble antigens forming complexes in the sera.
Antibodies↗
[Flavonols and flavones of vegetables. VIII. Flavones of carrot leaves (author's transl)].
The flavonoid constituents of carrot leaves (Daucus carota L. ssp. sativa) were separated by means of cellulose column chromatography, and the following compounds were obtained crystalline and identified by usual procedures: luteolin 7-beta-D-glucoside as the main flavon, luteolin 4'-beta-D-glucoside, luteolin 7-beta-D-glucuronide, apigenin 7-beta-D-glucoside, apigenin 7-rutinoside, chrysoeriol 7-beta-D-glucoside. Luteolin 7-rutinoside also was identified, but could not be obtained crystalline.
Chromatography↗
[Review on nonessential constituents of vegetables. II. Cruciferae (Brassica vegetables, radish, turnip, rutabaga, horse-radish) and gramineae (onion, leek, chive, garlic, asparagus) (author's transl)].
In this paper the hitherto known constituents of the titled vegetables except proteins, carbohydrates, triglyceride-fatty acids, and vitamins are reviewed, especially the volatiles, organic acids, phenolics, carotenoids and lipids.
Brassica↗
[Review on nonessential constituents of vegetables. I. Cumcumbers, melons, squashes and pumpkins, bell peppers, eggplants, peas, beans, and broad beans (author's transl)].
In this paper the known constituents of the vegetables mentioned in the title are reviewed, except for proteins, carbohydrates, triglyceride-fatty acids, and vitamins, with particular emphasis on volatiles, organic acids, phenolics, crotenoids, sterols, bitter principles, nonprotein-N-compounds.
Carboxylic Acids↗
Flavonoid glycosides and hydroxycinnamic acid esters of blackcurrants (Ribes nigrum). Phenolics of fruits 9.
The major flavonol glycosides of ripe blackcurrants (Ribes nigrum cv. Silvergieters Schwarze), myricetin 3-beta-D-glucopyranoside, rutin, and isoquercitrin, have been isolated in crystalline form. Analysis by thin-layer chromatography confirmed the occurrence of the 3-rutinosides and 3-glucosides of cyanidin and delphinidin. No free flavonoid aglycones could, however, be detected in the fresh berries. The major constituent fluorescing blue under ultraviolet light on paper and cellulose thin-layer chromatograms, was isolated and characterized as 1-O-caffeyl-beta-D-glucopyranose. Also isolated were 1-O-ferulyl- and 1-O-p-coumaryl-beta-D-glucopyranose. The occurrence fo hydroxycinnamyl-D-glucoses in blackcurrants does not appear to have been recognized previously.
Chromatography, Thin Layer↗
[Isolation and identification of flavon(ol)-O-glycosides in caraway (Carum carvi L.), fennel (Foeniculum vulgare Mill.), anise (Pimpinella anisum L.), and coriander (Coriandrum sativum L.), and of flavon-C-glycosides in anise. I. Phenolics of spices (author's transl)].
The flavonoid constituents of various spices were separated by means of chromatography on cellulose colums, and the following compounds were obtained crystalline: Quercetin 3-glucuronide from caraway, fennel, anise, and coriander; isoquercitrin from caraway and fennel; rutin from fennel and anise; quercetin 3-O-caffeylglucoside and kaempferol 3-glucoside from caraway; quercetin 3-arabinoside from fennel, and luteolin 7-glucoside, isoorientin and isovitexin from anise. Other constitutents which were however not obtained crystalline, but which could be identified by the usual procedures were kaempferol 3-glucuronide and kaempferol 3-arabinoside in fennel, apigenin 7-glucoside and a luteolin glycoside in anise, and isoquercitrin and rutin in coriander. The glycosides contained in the fruit of the four spices also occur in the leaves. Leaves of caraway and fennel in addition contain isorhammetin glycosides in low concentration.
Condiments↗
Further attenuated live measles vaccines: the need for revised recommendations.
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Aging↗
[Testicular torsion--acute scrotum].
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Acute Disease↗
[Rehabilitation of patients with myocardial infarct in the German Democratic Republic. Current status and further development].
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Germany, East↗
Risk of congenital abnormality after inadvertent rubella vaccination of pregnant women.
The risk to a fetus after rubella vaccination of its mother is unknown. The Center for Disease Control has compiled information from the pregnancies of 343 women inadvertently given rubella vaccine shortly before or after conception. The pregnancies of 145 women were terminated by therapeutic abortion, and rubella vaccine virus was recovered from the products of conception of nine women, including six of the 28 known to be seronegative to rubella at the time of vaccination. None of the 172 infants carried to term had either clinical or serologic evidence of rubella infection, including 38 infants of women known to be susceptible and 12 additional women estimated to be susceptible at the time of rubella vaccination. On the basis of the binomial distribution, the maximum risk of fetal infection after maternal rubella vaccination is between 5 and 10 per cent. The actual risk is probably less.
Abortion, Therapeutic↗