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K I Panchenko

Publications and source records attributed to K I Panchenko.

At least 19 recordsLinked to original sources
PubMed2006

[Leiomyomatosis of the lung].

The paper describes a case of diffuse leiomyomatosis of the lung in a 45-year-old female. Leiomyomatosis, a disease noted in females, is considered to include 4 types of multiple smooth muscle lesions: 1) benign metastasizing leiomyoma; 2) lymphangioleiomyomatosis; 3) leiomyomatous peritoneal dissemination; and 4) intravenous leiomyomatosis. The authors present a classification proposed by E. Martin who attempts to pool in it all multiple leiomyomatous lesions observed in females, males, and children.

Biopsy↗
PubMed2002

[Goodpasture syndrome].

Explore the source record for details and available documents.

Anti-Glomerular Basement Membrane Disease↗
PubMed1999

[Comparative sonographic, x-ray and morphological studies of the salivary glands in Sjögren's syndrome].

AIM: To define diagnostic value of parotid gland (PG) sonography in Sjogren's syndrome (SS) as compared to sialography and morphological changes of labial salivary glands (LSG). MATERIALS AND METHODS: Examination of 50 females with primary (20 patients) and secondary (30 patients) SS consisted of clinical, ultrasonic, x-ray and morphological investigations. RESULTS: Sonographically, PG in SS is characterized by nonhomogeneity of parenchymal picture detected in 75% of patients with primary and 50% of patients with secondary SS. Moderate and severe nonhomogeneity of PG parenchyma was seen in the stage of marked manifestations of chronic parenchymatous parotitis. CONCLUSION: Relationship between PG sonographic image in SS and morphological changes in LSG need further study. PG sonography may help in combined examination of SS patients.

Adult↗
PubMed1998

[Correlation between the count of the various intraepithelial mononuclear leukocytes and tumor progression in the stomach].

A study of 35 gastrobioptates sampled from benign epithelial proliferates, adenomas with advanced epithelial dysplasia and adenocarcinomas was conducted using standard original procedures of staining and DNA identification. Also, the method of direct immunoluminescence using fluoroesceinisothiocymate-labeled monoclonal antibodies against human antigens CD4, CD8, CD25 and CD45 was employed. It was found that, among microscopic intraepithelial mononuclear leukocytes, only few bear the immunohistochemical markers of activity. The distribution of intraepithelial mononuclear leukocytes in the stomach of a cancer patient is changed.

Adenocarcinoma↗
PubMed1997

[The clinico-morphological characteristics of sarcoid sialoadenitis].

Eight patients with sarcoidosis of the parotid salivary gland and submandibular area were examined. Primary involvement of the intra- or intra- and extraglandular lymph nodes with a probable secondary involvement of the salivary gland parenchyma was detected. Clinical, x-ray, and cytological findings were nonspecific, typical rather of a tumor of chronic sialadenitis. Histological findings were decisive for the diagnosis of sarcoidosis.

Adult↗
PubMed1997

[Clinical significance of Willebrand's factor antigen in patients with primary Sjogren's syndrome].

Concentration of von Willebrand's factor antigen (WFAg) was measured by solid phase enzyme immunoassay in the blood serum of 17 female patients (mean age 56.7 +/- 12.1 years) with primary Sjogren's syndrome (PSS) lasting, on the average, 4.1 +/- 1.5 years. Mean WFAg level in patients with PSS was equal to 2.56 +/- 1.4 IU/ml and exceeded significantly that of donors' (1.06 +/- 0.34, p < 0.001). In 9(53%) of 17 patients WFAg concentration was higher than normal (> 2.1 IU/ml). WFAg mean levels and frequency of its elevation did not differ significantly in patients with chronic parotitis, enlarged salivary glands, arthralgia/arthritis, lymphadenopathy, lung lesions, polyneuropathy and patients free of the above symptoms. In patients with myalgia, Raynaud's syndrome, skin vasculitis and vascular diseases WFAg concentrations were higher than in patients without them. There was no significant correlation between WFAg level and ESR, concentration of C-reactive protein, presence of rheumatoid and antinuclear factors.

Adult↗
PubMed1995

[The effect of basic therapy on the morphological picture of the rectal mucosa in patients with rheumatoid arthritis].

140 rectal mucosa biopsies were obtained from 86 patients with rheumatoid arthritis (RA), from 54 RA patients prior to or after a year basic therapy with either methotrexate or sulfa drug (sulfasalazine or salazopyridazine). 80% of the examinees exhibited large macrophages, lymphoid follicules, IgM- and IgG-containing cells. The knowledge of the initial morphologic changes in the rectal mucosa from RA patients helps predict efficacy of methotrexate or sulfonic drug treatment. Rectoromanoscopy with biopsy proved important diagnostic tool in RA capable of differentiating the disease variants, prompting valid therapeutic approach with control of the treatment results.

Adult↗
PubMed1994

The fate of free, pedicled and free vascularized cancellous iliac bone grafts and the effect on the healing of femoral osteotomy: an experimental study.

A new model for vascularized and nonvascularized iliac bone autograft transfer to a femoral shaft osteotomy site is presented in this experimental study. As demonstrated on roentgenograms taken at 4 to 6 weeks postoperatively, callus formation between vascularized grafts and recipient sites was 1.5 to 2 times faster than in the nonvascularized graft transfer. According to densitometric analysis, conventional free grafts lost more hydroxyapatite and restored their mineral structure at a slower rate than vascularized grafts. There was no difference between free vascularized and pedicled grafts in the rate of mineral deposition changes, but the pedicle grafts had more significant loss of bone density. Formation and mineralization of periosteal callus between the femoral-shaft fragments took place more rapidly in the first 12 weeks after pedicled bone transplantation. The correlation between the densitometric results and morphologic behavior of transplanted bones was examined. It was demonstrated that all of the grafts at the recipient site underwent remodeling into cortical bone. However, vascularized, and especially pedicled, grafts maintained their cancellous structure relatively longer.

Animals↗
PubMed1994

[The x-ray changes in the parotid salivary glands of patients with Sjögren's disease].

The data obtained upon sialography of the parotid glands (PG) in 28 patients with Sjogren's disease (SD) were compared to clinical SD manifestations, PG regional circulation and histological picture of the labial salivary glands. 24 patients exhibited classical sialography characterized by sialoectasias, enlarged ducts, obscure outlines of the latter. 4 sialograms displayed the duct narrowing, noncontrast parenchyma outlines, unclear images of sialoectasias. Severe xerostomia, marked dryness of the vermilion border, rare enlargement of the salivary glands and parotitis recurrences occurred more frequently in patients with narrow efferent PG ducts. These changes are attributed to vascular sclerosis, devascularization, stromal sclerosis and parenchymal PG atrophy.

Adult↗
PubMed1990

[The regional circulation of the parotid gland in Sjögren's disease].

Morphological methods, rheography and coagulography were used to study regional circulation in the parotid salivary gland (PSG) in 20 patients with the primary dry syndrome (Sjögren's disease). It has been established that in the presence of immune inflammation with the predominance of traits characteristic of delayed-type hypersensitivity, the vascular bed of the PSG undergoes transformation (changes in the tone, elasticity of vessels, blood flow rate, dystonia of resistive and atonia of capacitance microvessels, lymphostasis, and so forth). The changes in regional circulation are not infrequently coupled with a high concentration of fibrinogen and low fibrinolytic activity of the blood tending towards hypercoagulation.

Adult↗
PubMed1988

[Changes of the dermal-fascial autograft after transplantation on the vascular-nervous connections using a microsurgical technique].

In 56 dogs 86 microsurgical operations on transplantation of free dermal-facial autografts from the internal knee surface have been performed on the hidden vascular-nervous bundle. The animals have been observed for 1 day up to 1 year. The implanted grafts (63) have been studied, using a complex of anatomical, histological and roentgenological methods. During early time (up to 7 days) after the operation in the flap signs of edema, dystrophy and inflammatory infiltration of tissues predominate. The graft gets blood at the expense of the restored main artery and has no vascular connections with the surrounding tissues. Its nervous conductors are fragmented. During 2 weeks--1 month epidermis completely regenerates along the line of the dermal suture. In the flap bed mature granulations result in vascular connections with its surrounding tissues. These connections become stable by the end of the first month, this means that the graft has implanted. Its nervous fibers are also restored. Long-term observations demonstrate that the adaptive changes of the flap and its vascular bed are near to completion. By the end of the 1st year restoration of the main innervational connections of the graft takes place. According to the data obtained, the nervous conductors grow into it along the sewed hidden nerve and along the course of paravasal nerve plexuses. Across the scar from the surrounding tissues the dermal-fascial autograft does not reinnervate.

Animals↗