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Biomedical subjects

K Ia Gurevich

Publications and source records attributed to K Ia Gurevich.

At least 37 records · Page 2Linked to original sources
PubMed1984

[Use of thymalin in trauma patients].

A clinical study of the thymus preparation Thymalin was carried out in 23 patients with special reference to its use for prevention and treatment of infectious complications of critical traumas. The complex treatment can improve the clinical course of the trauma disease and normalize immune indices of the patients.

Adjuvants, Immunologic↗
PubMed1979

[Dependence of the effectiveness of massive blood transfusions on the state of cellular and humoral immunity in severe mechanical injury].

The observation of 97 patients with severe mechanical traumas has shown massive hemotransfusions performed within the first two days subsequent to trauma against the background of maximum reduced cell immunity to be much more efficient than the massive hemotransfusion performed within the 3d--7th days after trauma (against the background of repairing cell immunity).

Acute Disease↗
PubMedDate not supplied

[Therapeutic plasmapheresis in suppurative-septic surgery].

The results of the clinico-laboratory analysis conducted in 69 patients with varying forms of acute purulent surgical infections have shown that the therapeutic plasmapheresis is attended by the improvement of the disease clinical picture, and attenuation of endotoxicosis by day 3 after the perfusion. Indications and contraindications for plasmapheresis in critical patients are considered, the causes of unsuccessful plasmapheresis procedures are analyzed, the ways for the improvement of this operation are outlined.

Acute Disease↗
PubMedDate not supplied

[The use of extracorporeal detoxication methods in treating infectious disease patients].

The article summarizes the results of 1090 operations of extracorporal detoxication (ED) performed on severe infectious patients. ED was realized by methods of hemosorption, plasmasorption, plasmapheresis for viral hepatitis, typhoid diseases and mixed infections. For each category of patients indications and counterindications for ED application were worked out. Positive results were marked at 54-92% of cases, depending on nosological forms, period of illness and ED type. The authors propose a scheme of indications, optimal parameters and criteria for ED efficiency estimation. ED methods adopted for Afghan conditions can be successfully used in other regions with dry and hot climate.

Afghanistan↗
PubMedDate not supplied

[A sorption microfilter for blood transfusions].

A special device is developed to purify the conserved blood from microaggregations and toxic agents. It also decreases the CO2 level and the citrate content. The device combines the properties of a microfilter and a sorption column. The specifications of the device are given.

Adsorption↗
PubMedDate not supplied

[Feasibility of correction of blood aggregation properties in the course of extracorporeal hemosorption in atherosclerosis patients].

Aggregation and rheological properties of blood were evaluated in 20 atherosclerotic patients after cryoplasmosorption. The change of the patients' plasma for extracorporeally modified autoplasma reduced coagulation potential, enhanced fibrinolysis and suppressed anticoagulation systems. Clinical efficacy manifested in decreased frequency and duration of anginal episodes, intensity of intermittent claudication. Biochemically, cholesterol levels and atherogenic index lowering was evident.

Arteriosclerosis↗
PubMedDate not supplied

[Differentiated approach to the treatment of autoimmune ophthalmopathy].

The results of comprehensive examinations and therapy of 67 patients with autoimmune ophthalmopathy are presented. In 80% of the patients the disease coursed along with thyrotoxicosis, in 10% thyroid function was reduced because of autoimmune thyroiditis, and in the rest autoimmune ophthalmopathy was an individual entity. A staged therapeutic complex for the treatment of this condition is suggested, aimed at correction of thyroid function (stage 1), followed by pathogenetic therapy including antiinflammatory measures, glucocorticoids and nonsteroid antiinflammatory drugs to arrest aseptic inflammation in the orbit, and immunosuppressive therapy to correct the immunity shifts. After clinical and immunologic remission was achieved, courses of maintenance therapy (nonsteroid antiinflammatory drugs) were carried out for 3-5 months monitored by blood analyses and ophthalmologic examinations, immunity status tests, CT clinical data. Choice of the treatment strategy was governed by the morphologic variant of ophthalmopathy, immunologic activity of the process, disease severity and pattern. Such an approach helped achieve positive results and clinico-immunologic remission, as well as timely prevent the progress of the disease.

Adolescent↗
PubMedDate not supplied

[The detoxifying function of the pulmonary parenchyma in patients with acute infectious lung destruction].

The study of arteriovenous ratio of medium-molecular oligopeptides level in 32 patients with acute infectious lung destructions has established an important detoxicating role of the lungs in endotoxemia syndrome during pulmonary-pleural suppurations. It has been found that, with the pronounced endotoxemia syndrome, during catabolic phase of the disease the lungs turn from toxin filter into their source. Detoxicating capacity of the lung parenchyma was shown to be more dependent on the severity of general metabolic disturbances than on the dissemination of suppurative lung destruction.

Acute Disease↗