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K J Reynolds

Publications and source records attributed to K J Reynolds.

5 recordsLinked to original sources

In vitro performance test system for pulse oximeters.

An in vitro system was developed capable of testing the accuracy and reproducibility of pulse oximeter readings. The pulse oximeter probe receives signals through a pulsating blood cuvette. The development of the design of the cuvette is described. Using the final design (or 'model finger'), a comparison is made between readings from a Datex Satlite pulse oximeter (SpO2) and saturation values obtained by use of a multi-wavelength bench oximeter (SaO2). Linear regression analysis of the data gives SpO2 = 0.88 SaO2 + 11.2 (r = 0.979, p < 0.001).

Fingers

Response of 10 pulse oximeters to an in vitro test system.

Pulse oximeters are often used in situations in which severe hypoxaemia may occur. We have developed an in vitro system to test the accuracy of pulse oximeter calibration. The probe of 10 different oximeters was attached to a model finger in an in vitro blood circuit, and pulse oximeter readings (SpO2) were compared with multi-wavelength in vitro oximeter readings (SO2) over a range of SO2 values from 50 to 100%. The oximeters tested varied widely in their accuracy and linearity. We conclude that the system can test the accuracy, reproducibility and linearity of response of pulse oximeter readings at low oxyhaemoglobin saturations.

Calibration

Temperature dependence of led and its theoretical effect on pulse oximetry.

Ambient temperature is known to affect the emission spectrum of a light-emitting diode (LED). This study has investigated the effect of changes in ambient temperature on the emission spectra of two LED with peak emission wavelengths similar to those used in pulse oximetry. There was a 5.5-nm increase in the peak wavelength for a 660-nm LED, and a 7.8-nm increase in the peak wavelength for a 950-nm LED as temperature increased from 0 to 50 degrees C. Using a simple theoretical model based on the Beer-Lambert law, the effect of these shifts in wavelength on pulse oximeter accuracy was examined and found to be negligible over the temperature range studied.

Electrodes

The effect of varying LED intensity on pulse oximeter accuracy.

Most pulse oximeters automatically alter the intensity of their light-emitting diodes (LEDs) according to the absorption of the finger, toe or earlobe to which they are attached. This paper investigates the effect of changing LED intensity on pulse oximeter accuracy. Our results show that the peak wavelength of a red LED typically increases by 8 nm as its intensity is increased ten-fold. To determine whether this shift introduces a significant error, a simple theoretical model based on the Beer-Lambert law is used. The model predicts that a 10:1 change in LED intensity results in a 2.5% error at 50% arterial oxygen saturation (SpO2). At high saturations (SpO2 greater than or equal to 85%) the model predicts little loss of accuracy and thus any effect due to changes in LED intensity will be apparent only at low saturations.

Equipment Design