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Biomedical subjects

K K Gupta

Publications and source records attributed to K K Gupta.

At least 19 recordsLinked to original sources

Subretinal fluid in the diagnosis of posterior scleritis.

The etiology of subretinal mass lesions is very difficult to establish. A 28-year-old man presented to us with an area of choroiditis, which progressed, despite corticosteroid and antibiotic therapy, to an exudative retinal detachment, secondary glaucoma and a painful blind eye. To develop a means of identifying the cause of such lesions, we did a subretinal fluid tap prior to enucleation. Cytopathology showed only inflammatory cells and the final histopathological diagnosis was that of a granulomatous scleritis.

Adult

Fracture of the navicular sesamoid bone: a case report.

The case history of a 45-year-old female patient who sustained a fracture of the right navicular sesamoid bone, probably due to sudden stretching of the tibialis posterior muscle, is described, and the literature briefly reviewed.

Female

Evidence for coupled synthesis of mRNA for ribosomal proteins and rRNA.

Two-dimensional gel electrophoresis revealed quantitative differences in the 35S-methionine labeled proteins synthesized in vitro in the wheat germ system containing poly A(+) mRNA of normal liver, regenerating liver or Novikoff hepatoma cells. A group of low molecular weight proteins which comigrated with proteins of 40S ribosomal subunits were synthesized in a much greater concentration with the poly A(+) mRNA from the latter two sources. This correlates with increased synthesis of ribosomal proteins in regenerating liver or tumors which is temporally coupled with the increased nucleolar synthesis of rRNA precursors.

Animals

Macroaneurysms of the retinal arteries.

Six patients with spontaneous retinal and/or vitreous hemorrhages were found, on evaluation by fluorescein angiography, to have macroaneurysms involving the major retinal arteries. All showed evidence of other vascular disease. With absorption of the hemorrhages, five patients experienced appreciable improvement in vision. The aneurysms appeared to diminish in size as a result of fibrous changes within the arterial walls. In one patient, however, a second vitreous hemorrhage occurred several months later. The possibility of repeated hemorrhage suggests that more consideration should be given to treatment of these aneurysms.

Aged