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Biomedical subjects

K Katevuo

Publications and source records attributed to K Katevuo.

At least 37 records · Page 2Linked to original sources

Late compression neuropathies after Colles' fractures.

Conservative management of 166 Colles' fractures was associated with a 12% rate of late compression neuropathies (mean follow-up period, 28 months). Compression of the median nerve (8%) was twice as common as ulnar nerve compression (4%). Eighty-five percent of the patients with median nerve compression had malunion with radial collapse with or without other deformities (dorsal angulation/radial displacement). Patients with ulnar nerve compression had either malunion with radial collapse or volar subluxation of the ulnar head in those fractures that healed with dorsal angulation. Patients without nerve complications showed a significantly lower rate of malunions. These results demonstrate that anatomic derangements play a role in the development of late compression neuropathies following Colles' fractures.

Adolescent↗

Early surgical exploration and epineural repair in birth brachial palsy.

The management of birth brachial palsy (Erb-Duchenne, Klumpke) has been traditionally conservative, and that is why the condition leaves some patients with impaired upper limb function for life. Development of anaesthesiology and microsurgical techniques have made safe early surgical repair of selected palsies possible. A 12 years' experience of early exploration of 11 patients aged from 2 weeks to 7 months is evaluated. The technique of direct epineural repair of ruptured roots has been successful in the early treatment of birth palsy. In the follow-up of 1 to 13 years after operation 7/11 patients regained good to excellent hand function.

Birth Injuries↗

Diagnosis and treatment of renal angiomyolipoma.

A series of nine patients surgically treated for histologically verified renal angiomyolipoma is presented. Only one patient had extrarenal stigmata of tuberous sclerosis. No evidence of malignancy was found. In three cases a preoperative diagnosis was achieved with computed tomography (CT), use of which is recommended in evaluation of renal tumours. Six angiomyolipomas were solitary and three bilateral. Abdominal or flank pain was present in eight cases and perirenal haemorrhage in four. Solitary tumours were treated with nephrectomy. For bilateral tumour, nephrectomy and conservative renal surgery were used in two cases and bilateral nephrectomy and kidney transplantation were performed in the third case. When adipose tissue containing renal tumour is demonstrated at CT, conservative surgery should be considered.

Adult↗

Computed tomography of the pituitary fossa in primary hypothyroidism. Effect of thyroxine treatment.

Computed tomography of the pituitary fossa was performed in 12 patients with primary hypothyroidism before and after thyroxine treatment. In three, herniation of the diaphragma sellae precluded accurate measurement of the density of the hypophysis. Eight of the remaining patients showed abnormally increased density of the pituitary gland after intravenous injection of contrast substance which was significantly correlated with the serum TSH-level (r = 0.913, P less than 0.001). After thyroxine treatment the intrasellar density decreased substantially in all but one. We suggest that the observed contrast enhancement reflects increased pituitary circulation associated with the augmented function of TSH-producing cells in response to thyroid hormone deficiency.

Adolescent↗

Skeletal changes in dentists and farmers in Finland.

Two groups were studied: dentists and farmers from the Turku area. Radiologic examination of both groups included the spinal column, rib cage and shoulder joint. Spondylosis of the cervical spine was present in 68 (52.1%) of the dentists and 59 (19.2%) of the farmers. Lumbar spondylosis was more common among farmers than among dentists in the corresponding age group. Changes in the shoulder joint occurred significantly more often in dentists than in farmers. The findings in this study indicate that dentists appear to belong to the group doing heavy work.

Adult↗

Computed tomography in a case of ophthalmoplegia syndrome.

Until now the radiological diagnosis of the Tolosa-Hunt syndrome has been made on orbital venography or arteriography. A case of Tolosa-Hunt syndrome, studied using computed tomography (CT), indicates that CT may be valuable in confirming the clinical diagnosis.

Dexamethasone↗

Direct coronal CT: an aid to the diagnosis of sellar lesions.

The qualities of the CT scanners used have a decisive influence on the results presented in various papers dealing with sellar CT examinations. Our conclusions are presented with this in mind. In the great majority of cases, direct coronal CT through the sellar area is available and gives essential information about this region. The size and origin of a tumour can be determined and differential diagnosis between a tumour and an empty sella is possible. Coronal scanning must be considered a necessary part of sellar region CT. The use of lateral digital localizer seems essential in order to avoid the main shortcoming of this modality, namely artifacts caused by metallic dental fillings. However, in a certain significant number of cases difficulties still exist. Artifacts cannot always be avoided and diagnostic slices cannot then be obtained. The differential diagnosis between an empty sella and a cystic lesion, between different tumour types or between an aneurysm and tumour may also sometimes be impossible. Computer histographic analysis, sequential or dynamic CT studies as well as carotid angiography may increase the chances of differential diagnosis between neoplasms, and carotid angiography is essential in the detection of vascular lesions. The problem of truly reliable microadenoma detection has not so far been solved. The significant frequency of examinations spoiled by artifacts emphasizes the need for high quality reconstructions and also points to the fact that metrizamide cisternography with hypocycloid tomography still has a definitive role in radiological examination of the sellar area.

Adolescent↗

Serial nuclear magnetic resonance (NMR) imaging in patients with cerebral infarction.

Seven patients with supratentorial infarction were studied by means of serial nuclear magnetic resonance imaging using saturation recovery (SR) and proton density (PD) sequences. The earliest changes were visible in the more sensitive T1 dependent images (SR) and may reflect the cytotoxic component of ischemic brain edema. Further progress was also clearly discernible in the PD images and may mainly reflect the slower vasogenic component of ischemic brain edema. Nuclear magnetic resonance imaging seems to provide a new approach to early diagnosis of ischemic brain infarction. Furthermore, it may elucidate some aspects of the pathophysiology of ischemic stroke in man.

Adult↗

Is chronic brain damage in boxing a hazard of the past?

Of fourteen boxers with a mean age of 31 years who had been Finnish, Scandinavian, or European champions, only one showed deficits in neurological status and he and one other had had episodes of inappropriate behaviour which were attributed to boxing. However, computed tomography revealed pathological findings attributable to brain injury in four of six professional and one of eight amateur boxers. Two of the professionals and four of the amateurs had electroencephalographic abnormalities which may have been caused by brain injury. Twelve of the boxers had psychological test results which suggested brain injury, although only two professionals had definite deviation from normal. The results indicate that modern medical control of boxing cannot prevent chronic brain injuries but may create a dangerous illusion of safety. The only way to prevent brain injuries is to disqualify blows to the head.

Adolescent↗

The effect of intravenously administered sincalide on the human gallbladder during oral cholecystography.

Sincalide, the C-terminal octapeptide fragment of the cholecystokinin, was used to contract the gallbladder during routine oral cholecystography in 18 patients. In 14 patients clinically important contraction occurred. The average reduction in gallbladder size for these patients was 32.7% of the preinjection size (range 15.1%-67.9%). Within 8-12 minutes cystic duct visualisation occurred in 8 and common bile duct visualisation in 3 patients. Spasm of the gallbladder neck was found in 2 cases. The blood pressure and heart rate did not change significantly during the study. Six patients felt slight nausea for 1-4 minutes and two vomited. We conclude that sincalide may be useful in biliary tract function studies in special clinical conditions (i.e. upper abdominal pain with unknown aetiology).

Adult↗

Sodium taurocholate, ineffective as an adjuvant in oral cholecystography.

The effect of 6 g sodium taurocholate on the visualization of the gall bladder with calcium iopodate (Solu-Biloptin, Leiras, Schering AG) was studied on 140 patients with a control group of 99 patients. The administration of sodium taurocholate with a contrast medium did not improve the opacification of the gall bladder in oral cholecystography with calcium iopodate but induced a significant increase in side effects.

Adolescent↗

Angiography and computed tomography in the diagnosis of primary lymphoma of the brain.

Three patients with primary lymphomas of the brain are presented. The angiographic and computed tomographic (CT) appearances resembled the few cases reported previously. In all three cases angiography showed avascular tumours with little vessel displacement or involvement whereas the CT scans showed large strongly and homogeneously enhancing tumour masses. Neither method alone gives pathognomonic appearances, but taken together angiography and CT should suggest the diagnosis of this rare tumour.

Adult↗

Metrizamide cisternography with hypocycloid and computed tomography in sellar and suprasellar lesions.

Metrizamide cisternography with both hypocycloid and computed tomography was performed on 23 patients with a sellar or a suprasellar lesion. The degree of an extrasellar tumour extension or the presence of an empty sella was detected precisely. The procedure was easy to perform and the side-effects were mild to moderate in most patients. When used carefully this diagnostic method provides valuable information when choosing the appropriate treatment for patients with sellar or parasellar lesions.

Adult↗

The effect of drugs with different mechanisms of action on the contraction of the human gallbladder.

The effects of drugs with different mechanisms of action on the human gallbladder smooth muscle are reviewed. Sincalide, the C-terminal octapeptide fragment of cholecystokinin, caused a clinically important contraction of the gallbladder during oral cholecystography in 72% of the patients. Within 8-12 min cystic duct visualization occurred in 44% and common bile duct visualization, in 17%. On the other hand, the standard concentration meal (200 ml cream) caused a more reliable gallbladder contraction in 30 min. One tablet of Baralgin, i.v. proxyphylline (300 mg), and i.v. glycopyrrolate (0.2 mg) had no relaxing effect on the contracted gallbladder during oral cholecystography. Similarly, i.v. metoclopramide (20 mg) and i.v. prostaglandin E2 (25, 50, and 75 micrograms) were ineffective, whereas 1 ampule of Baralgin and 1 ampule of Palerol i.v. caused a significant dilatation. Litalgin i.v. 1 ampule, i.v. papaverine (40 mg), and sublingual nitroglycerin (0.5 mg) had a slight relaxing effect on the smooth muscle of the gallbladder. In an acute attack of pain in a patient with gallstones, i.v. administered Baralgin and Palerol seem to be effective; i.v. Litalgin, i.v. papaverine, and sublingual nitroglycerin may be of value in milder biliary tract disorders, but the benefit of i.v. proxyphylline, i.v. glycopyrrolate, and oral Baralgin is questionable. Metoclopramide can be used as an antiemetic drug in patients with gallstones.

Cholecystography↗