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Biomedical subjects

K Katevuo

Publications and source records attributed to K Katevuo.

49 records · Page 3Linked to original sources
PubMed1981

The effect of intravenously administered Palerol and Litalgin on the contraction of the human gallbladder.

One ampule of Palerol and one of Litalgin (combination preparations with vagolytic, smooth-muscle relaxing, and analgesic effects) were injected intravenously in a double-blind study in random order to 19 patients having a routine oral cholecystography. Palerol had a significant dilatation effect on the smooth muscle of the contracted gallbladder, but Litalgin only prevented further contraction caused by fatty meals. Side effects were minimal. Palerol seems to be useful in acute gallstone attacks.

Adult↗
PubMed1981

Aminophylline in ureterolithiasis: preliminary report.

Aminophylline (3 mg/kg i.v.) was injected in six patients with colicky pain caused by a ureter stone. In all but one this theophylline derivative caused a prompt and subjectively clear decrease in pain lasting from 30 min to 2 h. Serum levels over 12 microgram/ml were associated with good pain relief. A controlled study with an intravenous aminophylline infusion is warranted, because the pain-decreasing effect was too short-lasting after a single injection.

Adult↗
PubMed1979

Computer aided diagnosis of bone tumors.

Four radiologists, three of whom having no special expertise in bone tumor radiology, analysed 177 bone tumors. One of the radiologists, using a computer aided bone tumor program, performed significantly better than the other two at a comparable level of training and was able to compete successfully with the fourth radiologist experienced in bone diagnosis. The results validate the assumption that computer aided diagnostic programs may improve the diagnostic accuracy of radiologists having limited experience with the problem at hand.

Bone Neoplasms↗
PubMed1979

The effect of intravenously administered glycopyrrolate and orally given analgetic-spasmolytic combination preparation on the contraction of the human gallbladder.

The effects of intravenously administered glycopyrrolate 0.2 mg (n = 10, Group I) or one orally given analgesic-spasmolytic combination preparation tablet (n = 10, Group II) on the contraction of human gallbladder during control oral cholecystography were compared with patients without any medication (n = 10, Group III). Neither drug had any effect on the gallbladder contraction and, hence, their usefulness in a patient with pain caused by gallstones is questionable. Heart rates and blood pressures were constant in Groups II and III but in Group I glycopyrrolate occasionally caused slight tachycardia and elevated blood pressure. Only in Group I 2 patients had mild side-effects (anticholinergic).

Administration, Oral↗
PubMed1979

Common bile duct visualization with a nonvisualized gallbladder in oral cholecystography: radiological and surgical study.

A series of 203 cholecystectomied patients in which the gallbladder was not visualized in oral cholecystography is analysed. In 72 cases the common bile duct was seen. In 4 cases it was dilated. At operation, cholecystolithiasis was found in 189 cases, a calculus in the common bile duct in 3 cases, and a neoplasm in 3 cases. In 6 cases there was inflammation but no calculi. Administration of 2 g of sodium iopanoate on 2 successive days before the examination seems to result in frequent visualization of the common bile duct. It also seems to be an accurate method in biliary tract disease when the gallbladder was not adequately visualized.

Cholecystitis↗
PubMed1978

The effect of sublingually administered nitroglycerin on the contraction of the human gallbladder.

Nitroglycerin (0.5 mg) was administered sublingually either before (n = 10) or after (n = 10) a standard contraction meal (200 ml of cream) during oral cholecystography. In both groups the standard contraction meal caused a significant contraction of the gallbladder. Nitroglycerin had no significant dilatation effect; hence its benefit during an acute attack of pain in a patient with gallstones seems to be questionable.

Adolescent↗
PubMed1978

The effect of papaverine on the contraction of the human gallbladder.

In a double-blind study, 40 mg of papaverine (Group I) or the same amount of placebo (1.0 ml of physiological saline, Group II)was injected intravenously in 19 patients to study the effect of papaverine on the contractility of the gallbladder in connection with routine oral cholecystography. In both groups a standard contraction meal (200 ml of cream) caused a significant contraction of the gallbladder (at 30 minutes). Thereafter, intravenously administered papaverine significantly inhibited further contraction caused by the fatty meal, but no significant dilatation was observed. This difference between the two groups lasted throughout the whole study period to 60 minutes after the drug administration. This time period mainly consisted of the distributional alpha-phase of the drug concentrations determined by gas chromatography in the serum. Because no dilation effect on the gallbladder was found, the clinical spasmolytic response to papaverine during an acute attack of pain in a patient with gallstones seems to be questionable.

Adult↗
PubMed1978

The effect of intravenously administered proxyphylline and Baralgin on the contraction of the human gallbladder.

In subsequent studies 300 mg of proxyphylline (Group 1) and 1 amp Baralgin (Group 2) were administered intravenously to 20 patients in order to study the relaxing effect of proxyphylline and Baralgin on the contracted gallbladder in connection with routine oral cholecystography. After the standard contraction meal (200 ml cream) the intravenously administered proxyphylline had no relaxing effect on the human gallbladder, whereas Baralgin caused a significant dilation. The dilation effect lasted throughout the whole study period (60 min). Proxyphylline concentrations in the serum, determined by gas-liquid chromatography, proved to be on the therapeutic level which is said to be effective in the treatment of obstructive pulmonary disease. Because with proxyphylline no dilation effect on the gallbladder was found, the clinical spasmolytic response to proxyphylline during an acute attack of pain in a patient suffering from gallstones seems to be questionable. Baralgin caused a significant dilation effect on the gallbladder, and it seems to be a useful agent in an acute gallstone attack.

Adult↗
PubMedDate not supplied

The effect of metoclopramide on the contraction of the human gallbladder.

In a double blind study 45 patients were given either an i.v. injection of 20 mg Primperan (20 mg metoclopramide, Lundbeck, n = 15), 20 mg Metopram (20 mg metoclopramide, Leiras, n = 15) or a corresponding amount of physiological saline (n = 15) and the effect of metoclopramide on the human gallbladder was studied in x-ray examination of gallbladder. The gallstones do not appear to be a contraindication for the clinical use of metoclopramide as an antiemetic drug. No contraction of the gallbladder was demonstrated, even though metoclopramide has been shown to contact intestinal smooth muscle. Primperan caused more side effects than Metopram. Sedation seems to be the most common side effect of metoclopramide.

Cholecystography↗
PubMedDate not supplied

Magnetic resonance imaging of intracranial neoplasms at 0.02 tesla.

Sixty-five patients with single or multiple intracranial neoplasms were examined with an MR imager operating at 0.02 tesla. In 56 patients the diagnosis was histologically confirmed. All patients had an abnormal CT finding. MR images were positive in 59 cases, while the lesion remained undetected or equivocal in 6 cases (2 pituitary adenomas and 4 meningiomas). The MR signal intensity of several meningiomas was equal to that of normal brain tissue. Some astrocytomas were better delineated on MRI than on CT. For the study of pituitary lesions, the spatial resolution was unsatisfactory. The ultralow field MR imager was found to be sensitive for the detection of other intracranial neoplasms.

Adenoma↗
PubMedDate not supplied

A non-cystic mesenchymal hamartoma of the liver--an unusual case of an unusual entity. Case report and review of the literature.

We report here a case of non-cystic mesenchymal liver hamartoma in a young adult woman. The patient was preoperatively examined with ultrasound (US), computed tomography (CT) and angiography. US and CT revealed signs of a benign tumor in the left liver lobe. Angiographically the tumor had pathological blood vessels. Histologically it proved to be an unusual non-cystic form of benign mesenchymal hamartoma.

Adult↗