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Biomedical subjects

K Mattila

Publications and source records attributed to K Mattila.

At least 109 records · Page 6Linked to original sources
PubMed1979

Separation of the integral membrane glycoproteins E1 and E2 of Semliki Forest virus by affinity chromatography on concanavalin A-Sepharose.

The membrane glycoproteins E1 and E2 of Semliki Forest virus are of about equal size but can be separated from each other by affinity chromatography on a concanavalin A-Sepharose column in the presence of sodium dodecyl sulfate. The E1 protein eluted like glycopeptides containing two peripheral sugar branches composed of N-acetylglucosamine, mannose, galactose and sialic acid. The E2 eluted like glycopeptides containing only N-acetylglucosamine and mannose.

Carbon Radioisotopes↗
PubMed1978

Diagnosis of fractures of the head and neck with the aid of cylindrical pantomograms taken with a new device.

The use of cylindrical image layers in pantomographic roentgen diagnosis of fractures of the middle third of the face and base of the skull, is presented. Three dimensional pictures are presented from the horizontal, backward tilt (retroversion) and forward tilt (anteversion) projections as well as the projection of the base of the skull, which yield most information. Of these, the horizontal projection may be considered to be the projection which provides the best basic picture of the middle third of the face. The backward tilt projection reveals the bone structures of the central area and fractures in them best. Fractures in the lateral region are best seen in the forward tilt projection. The radiography of the base of the skull and the lateral walls on one film also presents a new application of the pantomographic technique. The positions of the patient used in taking these roentgenograms with a new pantomographic device developed for patients in a horizontal position are explained, and photographs of them presented. The future aims of this investigation series are referred to in the discussion.

Cervical Vertebrae↗
PubMed1977

Determination of the gonial angle from the orthopantomogram.

This study demonstrates that the size of the gonial angle can be determined from the orthopantomogram with the same degree of accuracy as from the generally used lateral cephalogram, the gonial angle being formed by the tangents of the lower border of the mandible and the distal border of the ascending ramus and the condyle on each side. It also shows that the right and left gonial angles can be quite easily determined individually from orthopantomograms, thus avoiding the disturbing influence of the superimposed images found on lateral cephalograms. It proves conclusively that the orthopantomogram is the more obvious choice for determination of the gonial angles.

Adolescent↗
PubMed1976

Protein-bound oligosaccharides of Semliki Forest virus.

Semliki Forest virus was grown in BHK cells and labeled in vivo with radioactive monosaccharides. Pronase digests of the virus chromatographed on Bio-Gel P6 revealed glycopeptides of A-type and B-type. (For the nomenclature see Johnson, J. and Clamp, J.R. (1971) Biochem. J. 123, 739-745.) The former was labeled with [3H]fucose, [3H]galactose, [3H]mannose and [14C]glucosamine, the latter only with [3H]mannose and [14C]glucosamine. The three envelope glycoproteins E1, E2 and E3 were isolated by sodium dodecyl sulfate-polyacrylamide gel electrophoresis and subjected to pronase digestion. The glycoproteins E1 and E3 revealed glycopeptides of A-type. E2 revealed glycopeptides of B-type. E2 yielded additionally a glycopeptide (Mr3100) which was heavily labeled from [3H]galactose, but only marginally from [14C]glucosamine, [3H]fucose and [3H]mannose. Whether this glycopeptide belongs to the A-type or not remains uncertain. The apparent molecular weights of the A-type units measured by gel filtration were 3400 in E1 and 4000 in E3; the B-type unit of E2 had an apparent molecular weight of 2000. Combined with the findings of our earlier chemical analysis these data suggest that E1 and E3 contain on the average one A-type unit; E2 probably contains one 3100 dalton unit plus one or two B-type units.

Amino Acids↗
PubMed1976

Follow-up study of apicoectomized molars.

The present material consists of 46 respected molars, 20 of which were located in the maxilla and 26 in the mandible. Altogether, 93 different roots were resected and 109 root fillings made. The follow-up study was made 1-6 years after the apicoectomy. The patients were examined clinically, special attention being paid to the subjective and objective symptoms shown by each apicoetomized tooth. Then a stereoscopic picture of the resected tooth and an orthopantomogram were taken. Of these 46 apicoectomized teeth, 33 (71%) showed complete healing, five (11%) were uncertain, four (9%) showed unsatisfactory healing, and four (9%) were extracted. When examining molars it seems reasonable to study each root as a separate case. Among the 93 apicoectomized roots, there were 75 (81%) cases of complete healing, six (6%) of uncertain healing, four (4%) of unsatisfactory healing, and eight (9%) extractions. There was no difference between the groups of radicular cysts and periapical granulomas in healing. The percentage of cases of complete healing was higher when approximately one-half of the roots were resected than when approximately one-third were resected. The orthograde root filling made in connection with resection was found better than the retrograde or the earlier orthograde filling. It was also found that when several periapical lesions were present in the other teeth, the number of complete healings in the group of resected teeth was less.

Adolescent↗