Biomedical subjects

K-P Hermann

Publications and source records attributed to K-P Hermann.

4 recordsLinked to original sources

PubMed2005

[Clinical results of digital mammography].

Digital mammography is the technology of the future in breast diagnosis. This article provides an overview of all digital mammography units admitted by the Food and Drug Administration (FDA), results of clinical studies, soft copy reading, CAD (computer aided detection), and presents an overview on possible further developments. It is obvious that clinical results are equivalent to conventional screen film mammography and digital mammography.

Breast Neoplasms↗

PubMed2004

[Phantom study for the detection of simulated lesions in five different digital and one conventional mammography system].

PURPOSE: Experimental phantom study for the detection of simulated lesions with five different digital and one conventional screen-film mammography system. MATERIALS AND METHODS: Three radiographs were obtained at various configurations of the phantom with one conventional screen-film system (Mammomat 3000 N) (Siemens), five digital systems (high resolution computed radiography system [Fuji/Siemens], one a-Si detector [GE Medical Systems], two a-Se detectors [Siemens; Hologic / Lorad] and one CCD detector [Fischer Imaging]), applying the same exposure parameters. The Wisconsin Mammographic Random Phantom, Model 152 A, was used. Five investigators with different experience in mammography (3 months to more than 4 years) evaluated the 18 randomly selected radiographs. RESULTS: No significant differences were found in the detection rate of simulated breast lesions for conventional screen-film mammography (84.9 %), high resolution computed radiography (86.7 %) and digital mammography with an a-Si detector (89.8 %). Highly significantly better results (p < 0.001) were found with the two a-Se systems (97.3 %) and the CCD system (100 %). CONCLUSION: Conventional screen-film mammography can be replaced by high resolution computed radiography and digital mammography with a-Si-, a-Se- and CCD-detectors. This has to be confirmed in further clinical studies.

Computer Simulation↗

PubMed2003

Dose reduction in full-field digital mammography: an anthropomorphic breast phantom study.

The aim of this study was to evaluate the potential for radiation dose reduction by using other beam qualities in full-field digital mammography (FFDM) compared with screen-film mammography (SFM). FFDM was performed using an amorphous silicon detector with a caesium iodide scintillator layer (Senographe 2000D, GE, Milwaukee, USA). SFM was performed using a state-of-the-art conventional system (Senographe DMR, GE, Milwaukee, USA) with a dedicated screen-film combination. An anthropomorphic breast phantom with superimposed microcalcifications (50-200 microm) was used to evaluate the detectability of microcalcifications. Contact mammograms and magnification views (m=1.8) performed with both the digital and the screen-film system were compared. Images were exposed automatically. Molybdenum/Molybdenum (Mo/Mo) anode-filter combination, 28 kVp and 63 mAs were selected by the automatic optimization of parameters (AOP) of the conventional system. This exposure protocol (protocol A) was also used as baseline for the digital system. Dose reduction in digital mammography was achieved by using protocol B with Mo/Rh and 31 kVp and protocol C with Rh/Rh and 32 kVp. The detectability of microcalcifications was assessed by 3 experienced readers with a confidence level ranging from 1 to 5. A receiver operating characteristic (ROC) analysis was performed. In protocol A the area under the ROC-curve (A(z)) for contact views performed by the screen-film system was 0.64 and for those performed with the FFDM system 0.68. The A(z) values were 0.74 in protocol B and 0.65 in protocol C for the digital system. For the conventional and digital magnification views A(z) values were 0.71 and 0.79, respectively. For protocol B the A(z) value was 0.81 and for protocol C it was 0.76. There is no statistically significant difference in the A(z) values for the different protocols in digital mammography and no significant difference from the screen-film system. A potential for dose reduction by using other beam qualities seems to be possible with this digital system.

Anthropometry↗

PubMed2002

Magnification mammography: a comparison of full-field digital mammography and screen-film mammography for the detection of simulated small masses and microcalcifications.

The objective of this study was a comparison of a full-field digital mammography (FFDM) system and a conventional screen-film mammography (SFM) system with respect to the detectability of simulated small masses and microcalcifications in the magnification mode. All images were obtained using 1.8 times magnification. The FFDM images were obtained at radiation dose levels of 1.39, 1.0, 0.7, 0.49 and 0.24 times that of the SFM images. A contrast-detail phantom was used to compare the detection of simulated lesions using a four alternative forced-choice reader study with three readers. The correct observation ratio (COR) was calculated as the fraction of correctly identified lesions to the total number of simulated lesions. Soft-copy reading was performed for all digital images. Direct magnification images acquired with the digital system showed a lower object contrast threshold than those acquired with the conventional system. For equal radiation dose, the digital system provided a significantly increased COR (0.95) compared with the screen-film system (0.82). For simulated microcalcifications, the corresponding difference was 0.90 to 0.72. The digital system allowed equal detection to screen-film at 40% of the radiation dose used for screen film. Digital magnification images are superior to screen-film magnification images for the detection of simulated small masses and microcalcifications even at a lower radiation dose.

Breast Diseases↗