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Biomedical subjects

L A Lobes

Publications and source records attributed to L A Lobes.

At least 19 recordsLinked to original sources
PubMed1991

Management of ocular penetration from injection of local anesthesia preceding cataract surgery.

We herein describe 12 patients who suffered penetration or perforation of the globe during injection of a local anesthetic before cataract surgery. Minimum follow-up was 6 months. Six eyes had a final visual acuity of 20/50 or better and an attached retina. Four eyes had an attached retina with a visual acuity of 20/80 to 2/200. Two eyes were anatomic failures because of a recurrent retinal detachment complicated by proliferative vitreoretinopathy. These cases show that retinal penetrations without retinal detachment may be treated effectively with photocoagulation. Vitreous surgery is recommended when the retinal penetration is associated with a retinal detachment. Eyes with a dense vitreous hemorrhage and a suspicion of a penetrating injury should either be followed up closely with echography or should undergo vitreous surgery since the extent of the injury cannot be determined.

Adult↗
PubMed1987

A psychophysical technique for measuring cone photopigment bleaching.

A new, clinically applicable test has been developed to measure the bleaching of the foveal cone photopigments. This noninvasive test is called steady-state color matching. Steady-state color matching is based on the dependence of a color match on the optical density of the cone photopigments. By measuring the color match as a function of retinal illuminance, it is possible to compute the optical density of the cone photopigments at each illuminance. Thus, abnormalities of photopigment bleaching can be detected. This study demonstrates that the technique is readily performed by a clinical population. Patients with central serous retinopathy and retinitis pigmentosa are shown to have low effective optical densities.

Adolescent↗
PubMed1987

Cone photopigment bleaching abnormalities in diabetes.

We have used a color-matching technique to obtain estimates of the optical density of cone photopigments as a function of retinal illuminance in patients with insulin-dependent diabetes mellitus (IDDM). We found that the half-bleach illuminance of some patients is abnormally high. That is, it takes more light to bleach an equivalent amount of photopigment in these patients. Since low illuminance color matches for these patients are normal, this implies that these patients have normal amounts of photopigment, but the photopigment is not bleaching normally. This result clearly points to abnormalities in the outer retina of these diabetic patients. The most likely causes of this abnormality are either decreases in the ability of the cones to absorb light, or an increased rate of regeneration of the cone photopigments.

Adolescent↗
PubMed1986

Hepatitis B infection in ophthalmologists.

A seroepidemiologic survey of ophthalmologists in Western Pennsylvania was performed to define the hepatitis B virus (HBV) exposure risk for this subspecialty population. Of 70 participating ophthalmologists, only 5 (7.1%) had serologic evidence of prior hepatitis (positive hepatitis B surface antibody and antibody to the core antigen of hepatitis B). No participants were found to be HBsAg (hepatitis B surface antigen) positive. The infection rate for ophthalmologists appears lower than that previously described for physicians involved in surgical and nonsurgical medical specialties. However, caution is still recommended since hands and surgical instruments may become contaminated with HBV from the blood and secretions of hepatitis B patients or carriers.

Adult↗
PubMed1985

Pupillary abnormalities induced by argon laser photocoagulation.

Twenty-two patients who underwent panretinal argon laser ablation for proliferative diabetic retinopathy were studied for post-laser pupillary abnormalities. All 22 patients developed sector palsies of the iris sphincter. Fifteen demonstrated supersensitivity to 0.125% pilocarpine in the treated eye. Four of 12 patients developed accommodative paresis in the treated eye. Six showed light near dissociation in the treated eye. The sector palsies and associated cholinergic supersensitivity of the iris sphincter, the accommodative paresis, and light near dissociation imply that the laser treatment damaged the ocular parasympathetic innervation.

Adult↗
PubMed1984

Presumed toxoplasmic papillitis.

Six patients with ocular toxoplasmosis are described whose only active site of inflammation was at the optic nervehead. These patients presented with severe papillitis, vitreous inflammation, and sector or nerve fiber bundle field defects. Because of the papillitis and the absence of other typical foci of retinitis to suggest toxoplasmosis in these patients, the initial diagnoses were usually incorrect. These cases are presented to familiarize ophthalmologists with this unusual cause of papillitis.

Adolescent↗
PubMed1983

Syphilitic neuroretinitis.

Four patients (three men, 32, 43, and 53 years old, and one 37-year-old woman) with syphilitic neuroretinitis had cerebrospinal fluid evidence of neurosyphilis. Therapy failed in one patient given penicillin G benzathine intramuscularly and it may have failed in a second patient. Another treatment failure occurred in a patient given tetracycline orally. Intramuscular penicillin G benzathine or intramuscular penicillin G procaine in doses of less than 2.4 million units/day does not produce spirocheticidal drug levels in the cerebrospinal fluid. All four patients improved after high-dose treatment with aqueous penicillin G.

Administration, Oral↗
PubMed1981

Computerized axial tomography in the detection of intraocular foreign bodies.

CAT scanning was used in the localization of intraocular and periorbital foreign bodies in 36 consecutive patients. The method was found to be convenient, well-tolerated by the patient, and provided accurate and useful clinical information. Six cases are described to illustrate clinical situations where traditional localizing methods were unable to supply satisfactory information and where CAT scanning proved to be of significant assistance. This included uncooperative patients, multiple foreign bodies, anterior foreign bodies, and foreign bodies adjacent to the posterior scleral wall.

Adult↗
PubMed1981

Panfunduscope contact lens for argon laser therapy.

The Rodenstock panfunduscope lens adds significantly to the safety of argon laser pan retinal ablation by allowing easy and constant visualization of the relationship of burns to the fovea. One can constantly monitor the overall pattern of photocoagulation being achieved, thereby eliminating skipped areas. The increased safety and speed of the procedure may benefit both surgeon and patient.

Argon↗
PubMed1981

Polytetrafluoroethylene in experimental retinal detachment surgery.

Expanded polytetrafluoroethylene (PTFE) material was evaluated as an adjunctive material for retinal detachment surgery. A 4 mm sponge was wrapped in a 4 mm diameter tube of PTFE and sutured episclerally. Additionally, PTFE was rolled and sutured into an episcleral pocket as an implant material. Microscopic sectioning demonstrated a minimal inflammatory response and ingrowth of connective tissue into the PTFE. The intrascleral PTFE had also become successfully infiltrated with connective tissue, creating a thick, fibrovascular intrascleral implant. This material may prove useful in preventing extrusion of Silastic sponge exoplants, as a buckling element for intrascleral procedures, or as a covering for staphylomatous areas that require episcleral buckling.

Animals↗
PubMed1981

Diabetic retinopathy in Mauriac's syndrome. Paradoxical deterioration with improved metabolic control.

We report four children with marked short stature, hepatomegaly, and delayed adolescence. Initial funduscopy demonstrated only occasional microaneurysms in two children and a single intraretinal hemorrhage in another. Improved control required large increases in insulin dosage. Growth rate improved significantly and hepatomegaly regressed. Puberty progressed rapidly in two older patients with poor final height. Paradoxically, with improved control, retinopathy progressed rapidly. One child with proliferative retinopathy in both eyes developed vitreous hemorrhage and blindness in one eye. Two required pan retinal photocoagulation with no further progression of their retinopathy. These rapidly progressive retinal changes remain unexplained. We advise caution when correcting metabolic derangements of diabetic patients who have been poorly controlled for a prolonged period.

Adolescent↗
PubMed1980

Technique for removing a fishhook from the posterior segment of the eye.

A man was admitted to the hospital with a penetrating injury to the eye caused by a fishhook. One of the current techniques for removing cutaneously embedded hooks was used to remove it. This technique, in conjunction with detachment surgery, resulted in the successful restoration of vision in our patient. To our knowledge, this is the first report of the successful removal of a fishhook that penetrated the retina and lay within the vitreous of the eye.

Eye Foreign Bodies↗
PubMed1980

Subretinal lesions following scleral buckling procedure.

In five patients, subretinal lesions developed several weeks after scleral buckling procedures for retinal detachment. The lesions appear to be subretinal, well circumscribed, dome shaped, yellow-orange unassociated with edema or disturbance of the overlying retina, and unaccompanied by overlying inflammatory cells in the vitreous. All were located temporal to the fovea in the posterior pole. The angiographic pattern was characteristic, showing obscuration of the usual appearance of the lamina choroidocapillaris. Throughout the angiogram, the lesion remained unchanged, showing no increasing hyperfluorescence or hypofluorescence. Final visual acuities were 20/40 or better in all five patients, with follow-up periods from three to seven months. There is some evidence to suggest that these lesions represent persistent, isolated pockets of subretinal fluid.

Adult↗