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Biomedical subjects

L A Lobes

Publications and source records attributed to L A Lobes.

30 records · Page 2Linked to original sources
PubMed1980

Incidence of cystoid macular edema following scleral buckling procedure.

Sixty eyes of 58 patients who underwent scleral buckling procedures were prospectively evaluated with postoperative fluorescein angiograms. Forty-three percent of these eyes showed angiographic cystoid macular edema (CME). Aphakic patients showed a 64% incidence of cystect the final visual acuity of aphakic patients but significantly reduced the visual recovery in the phakic group. The incidence of CME was not related to preoperative foveal detachment, duration of aphakia, duration of detachment, surgical approach, or refraction.

Aphakia↗
PubMed1979

Serum and vitreous Toxocara antibody in nematode endophthalmitis.

Five patients had a clinical diagnosis of nematode endophthalmitis and had both a serum and vitreous titer for Toxocara antibody. All five patients had a vitreous titer that was equal to or greater than the serum titer. Serum and vitreous obtained from ten other patients who had no evidence of endophthalmitis did not show this correlation. This study provides the clinician with a further understanding of the meaning of a positive enzyme-linked immunosorbent assay titer as well as an additional area for analysis in selected patients with ocular inflammation.

Antibodies↗
PubMed1978

The incidence of macular pucker after retinal detachment surgery.

In a study of 63 cases of macular pucker among 857 patients who underwent retinal detachment repair, we isolated several statistically significant risk factors: preoperative vision of less than 6/15 (20/50); preoperative presence of rolled edges, starfolds, or equatorial ridges; re-operations; choroidal hemorrhage; and age past 30 years. We were unable to confirm the risk associated with vitreous loss, vitreous hemorrhage, and degeneration. Results suggested that macular pucker after detachment surgery is produced by a membrane similar in origin to those causing other forms of periretinal proliferation.

Adult↗
PubMed1978

Armrest support for the slit-lamp delivery argon laser system.

We designed a new armrest for use at the argon laser. The arm support can be used on either the right- or left-hand side of slit-lamp tables of varying thicknesses. The continuous screw adjustment allows for easy height adjustment of the arm support. The construction of the armrest facilitates the adjustment and manipulation of a fundus contact lens, which is so necessary to the successful performance of argon laser photocoagulation.

Arm↗
PubMed1978

The electro-oculogram in human retinal detachment.

Thirteen patients with retinal detachment and surgical reattachment were studied with preoperative and multiple postoperative electro-oculograms. The light rise was reduced to a mean of 1.17 with detachment but recovered in 77% to a 1.87 ratio, the equivalent of the control eye. This recovery was complete within 66 days in 80% of patients who eventually did return to normal. This rapid recovery parallels the rapid return of anatomical, biochemical, and electrophysiological function demonstrated in experimental detachment.

Adolescent↗
PubMed1976

Ocular alkali burns in a large urban area.

A retrospective study of 63 ocular alkali burn victims revealed that black males in the 30 to 49 year age group were at highest risk, and that the burns were most commonly sustained via assault. One hundred eyes were involved, and in 38 cases there was bilateral involvement. There were 116 hospital admissions and 125 surgical procedures, yet 58% of the injured eyes had a final visual acuity of less than 20/200. Other demographic and socioeconomic factors were characterized to identify this event as a public health problem with well-defined risk factors and unsatisfactory treatment. Primary preventive measures are, therefore, necessary.

Adult↗
PubMedDate not supplied

Contribution of diabetes duration before puberty to development of microvascular complications in IDDM subjects.

The contribution of diabetes duration, both pre- and postpuberty, to the development of microvascular complications and mortality in diabetic subjects was investigated in three study populations from the Children's Hospital of Pittsburgh Insulin-Dependent Diabetes Mellitus (IDDM) Registry. Life-table analyses by total and postpubertal IDDM duration were used to evaluate differences in the prevalence of microvascular complications and diabetes-related mortality in subjects diagnosed before and during puberty, as defined by an age at IDDM onset marker of 11 yr for girls and 12 yr for boys. The prevalence of retinopathy and overt nephropathy in 552 White adult diabetic subjects (population 1, mean IDDM duration 20.8 yr was significantly greater in subjects diagnosed during puberty compared with those diagnosed before puberty. However, similar analyses by postpubertal duration showed no difference in microvascular complication prevalence between the two groups. These findings did not appear to be due to a confounding effect of age. Additional analyses of 239 adolescent diabetic subjects (population 2, mean duration 8.3 yr) revealed the same trend for the prevalence of retinopathy. Finally, results concerning the risk of diabetes-related mortality in a cohort of 1582 subjects (population 3, mean duration 12.9 yr) indicated that postpubertal duration of IDDM may be a more accurate determinant of the development of microvascular complications and diabetes-related mortality than total duration, and it is suggested that the contribution of the prepubertal years of diabetes to long-term prognosis may be minimal.

Adolescent↗
PubMedDate not supplied

Progressive retinopathy with improved control in diabetic dwarfism (Mauriac's syndrome).

We report four children aged 11-18 1/2 yr first seen 7-14 yr after the diagnosis of insulin-dependent diabetes. At presentation, all had marked short stature, two had hepatomegaly, and the older three had delayed adolescence. They had been severely underinsulinized. Initial funduscopy demonstrated only occasion microaneurysms in two children and a single intraretinal hemorrhage in another. The youngest was normal. Improved control required large increases in insulin dosage. Growth rate improved significantly and hepatomegaly regressed. Puberty progressed rapidly in two older patients with poor final height. Paradoxically, with improved control, retinopathy progressed rapidly with appearance of multiple microaneurysms, nerve fiber layer infarctions, intraretinal microangiopathic changes, hemorrhages, exudates, and macular edema in all the patients and severe proliferation changes in three. One child with proliferative retinopathy in both eyes developed vitreous hemorrhage and blindness in one eye. Two required panretinal photocoagulation with no further progression of their retinopathy. These rapidly progressive retinal changes remain unexplained. We advise caution when correcting metabolic derangements of diabetic patients who have been poorly controlled for a prolonged period.

Adolescent↗