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L A Parolis

Publications and source records attributed to L A Parolis.

42 records · Page 3Linked to original sources
PubMed1988

A structural investigation of the capsular polysaccharide of Klebsiella K69.

The structure of the capsular polysaccharide isolated from Klebsiella serotype K69 has been investigated by a combination of chemical and spectroscopic methods. The repeating structure of the deacetylated polysaccharide is shown to be of the "3 + 1 + 1" type, and it carries a 1-carboxyethylidene acetal at positions 4 and 6 of a terminal galactosyl group. The location of acetyl groups in the polysaccharide has not been established. The repeating unit of the deacetylated polysaccharide has the following structure. (Formula: see text).

Carbohydrate Conformation↗
PubMed1987

The structure of the neuraminic acid-containing capsular polysaccharide of Escherichia coli serotype K9.

The acidic capsular polysaccharide isolated from Escherichia coli O9:K9:H12 was investigated by using n.m.r. spectroscopy, methylation analysis, periodate oxidation, and bacteriophage-borne enzyme degradation. The polysaccharide, the structure of which is shown below, is the third E. coli capsular polysaccharide reported to contain neuraminic acid, the others being the K1 and K92 polysaccharides, and it is the first in the E. coli series shown to contain a 4-linked neuraminic acid unit. (formula; see text).

Carbohydrate Conformation↗
PubMed1987

Structural investigation of the capsular polysaccharide from Escherichia coli O9:K37 (A 84a).

The structure of the capsular polysaccharide from E. coli O9:K37 (A 84a) has been studied, using methylation analysis, Smith degradation, and graded acid hydrolysis. The configurations at the anomeric centres were assigned by 1H-n.m.r. spectroscopy of the polysaccharide and its derivatives and oligosaccharide fragments. The polysaccharide has the following trisaccharide repeating-unit which is unique in the E. coli series of capsular polysaccharides in possessing a 1-carboxyethylidene group as the sole acidic function. (Formula: see text) E. coli capsular polysaccharides have been classified into seventy-four serotypes. The structures of about twenty of these polysaccharides have been elucidated, one of which, K29, has been reported to contain a 1-carboxyethylidene group. In continuation of a programme aimed at establishing the structural basis for the serology and immunochemistry of the E. coli capsular antigens, we now report on the structure of the capsular polysaccharide from E. coli O9:K37.

Carbohydrate Conformation↗
PubMed1986

The structural elucidation of the capsular polysaccharide of Klebsiella K68.

The structure of the capsular polysaccharide isolated from Klebsiella K68 bacteria has been elucidated by both chemical and spectroscopic methods. The structure is of the "3 + 1" type, similar in pattern to the structures of the polysaccharides of Klebsiella K11 and K57, having a single branch point on the uronic acid. The polysaccharide is shown to consist of the following repeating unit: (Formula: see text).

Carbohydrate Conformation↗
PubMed1985

A structural investigation of the capsular polysaccharide of Klebsiella K14.

The structure of the capsular polysaccharide isolated from Klebsiella serotype K14 has been investigated employing a combination of chemical and spectroscopic methods. The repeating structure is shown to be of the "4 + 1 + 1" type, and it carries a 1-carboxyethylidene acetal substituent at positions 4 and 6 of a terminal glucose residue. The polysaccharide is one of a group of only three Klebsiella polysaccharides that have been found to contain a galactofuranose residue in the repeating unit. The repeating unit has the following structure: (Formula: see text).

Carbohydrate Conformation↗