Biomedical subjects

L A Pavlova

Publications and source records attributed to L A Pavlova.

15 recordsLinked to original sources

PubMed2003

Electron-probe X-ray microanalysis of individual particles of solid snow sediment with size factor correction.

A technique is proposed for X-ray electron-probe microanalysis (EPMA) of individual particles of solid snow sediment. Two sample preparation procedures were used to analyze the sediments. The PAP-method and the original bi-exponential model were used for matrix correction and the calculation of elemental composition. A method of calculating composition has been developed for approximately spherical individual particles, comparable in size with an area of X-ray generation. An analytical expression is proposed for determining the composition of these particles, taking account of their size. Including the size factor reduces the error of composition determination from 0.5-45 to 0.2-22% relative percent, for particles in the size range 1-3 microm.

Journal Article↗

PubMed1999

[Investigation and identification of the antimicrobial component of the drug "Tomatol"].

Antimicrobial activity of Tomatol against laboratory strains of Escherichia coli ATCC 25922, Staphylococcus aureus ATCC 6538-P and Candida albicans ATCC 885-653 as well as against clinical isolates of Enterobacter spp., Streptococcus spp., Staphylococcus spp., Klebsiella spp. and Escherichia spp. was tested. Tomatol was shown to have a broad antimicrobial spectrum including gram-positive and gram-negative organisms and Candida. The TLC investigation demonstrated that the Tomatol antimicrobial component was that of a complex of organic acids such as succinic, citric, tartaric and others.

Anti-Bacterial Agents↗

PubMed1997

Novel polymeric solid-phase extraction material for complex biological matrices. Portable and disposable artificial kidney.

The replacement of conventional hemodialysis treatment for a patient with malfunctioning kidneys by providing him/her with a portable and disposable "artificial kidney" which is connected to implanted artery and veneous cannulas on a patient's wrist is discussed. During a continuous flow of blood, plasma diffuses through a plasmapheretic membrane, passes through a bed of plasmacompatible sorbent Styrosorb, and arrives at an ultrafiltration membrane. Vacuum-operated ultrafiltration removes excess water together with dissolved urea and other small molecules, and Stryosorb removes medium-sized toxic substances. The hemocompatibility of the sorbent is improved by chemical modification of the surface.

Biocompatible Materials↗

PubMed1995

[Antimicrobial and antitrichomonal activity of 5-nitroimidazole derivatives in an in vitro experiment].

The comparative study on the antimicrobial activity of metronidazole and its complex with cobalt sulfate showed that the complex formation increased 2-4 times the metronidazole activity against elective anaerobes. The study of the drug action on Trichomonas spp. revealed that as a result of the complexing with cobalt sulfate the metronidazole efficacy against the Trichomonas strains isolated from the discharge of a female patient with metronidazole resistant trichomoniasis increased, the activating effect of the complex on the host cells being suggested.

Cobalt↗

PubMed1992

[The prevention of the translocation of intestinal microflora after the rescue of an organism from a terminal state].

In experiments on guinea pigs, the animals were resuscitated from clinical death caused by the acute loss of blood and subsequently treated intragastrically with enterosorbents: activated carbon fibrous material, alone and in combination with polymyxin B, polyphepan (a lignin derivative), polymethyloxan hydrogel and the sorbent Enterocat. In the animals, not treated during the postresuscitation period, a high population level of enterobacteria and Gram-positive aerobic cocci was registered in the contents of the small and large intestines and their translocation to mesenteric lymph nodes, liver, spleen and blood was observed. The amount of lactobacilli in the small intestine was decreased. Enterosorbents were found to decrease a high population level of intestinal microflora, to prevent the translocation of Gram-positive aerobic cocci and to inhibit the penetration of enterobacteria through the enteric barrier in the postresuscitation period. Combined use of activated carbon fibrous material with polymyxin B proved to be most effective for the elimination of enterobacteria.

Acute Disease↗

PubMed1989

[Evaluation of the effectiveness of health-related improvement in working conditions of postal services employees].

Basing on the physiological and hygienic research performed after a series of prophylactic measures, it was established that the introduction of rational working conditions in combination with physically active rest influences most postively the functional neuro-muscular state of upper extremities in telephone operators and mail sorters, and has a positive bearing on the hemodynamic indices, CNS and regulatory mechanisms status of operators and mail sorters.

Humans↗

PubMed1989

[Isolation of Campylobacter jejuni and Campylobacter coli from children with acute intestinal diseases].

In this work the data obtained in the examination of 338 children with diarrhea, aged 5 days to 14 years, are presented. The methods used for the collection of samples and their storage till the moment of inoculation are described. The possibility of using the microscopic examination of Campylobacter-containing native feces is shown. The work resulted in the isolation of 85 C. jejuni and C. coli strains. As shown in this work, the isolation of Campylobacter depended on the age of children and the season. The etiological importance of Campylobacter for the development of acute enterocolitis and gastroenteritis in 10% of the children under examination is suggested.

Acute Disease↗

PubMed1988