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PubMed · 9061487

Novel polymeric solid-phase extraction material for complex biological matrices. Portable and disposable artificial kidney.

V A Davankov·L A Pavlova·M P Tsyurupa·D R Tur
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Abstract

The replacement of conventional hemodialysis treatment for a patient with malfunctioning kidneys by providing him/her with a portable and disposable "artificial kidney" which is connected to implanted artery and veneous cannulas on a patient's wrist is discussed. During a continuous flow of blood, plasma diffuses through a plasmapheretic membrane, passes through a bed of plasmacompatible sorbent Styrosorb, and arrives at an ultrafiltration membrane. Vacuum-operated ultrafiltration removes excess water together with dissolved urea and other small molecules, and Stryosorb removes medium-sized toxic substances. The hemocompatibility of the sorbent is improved by chemical modification of the surface.

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Biocompatible MaterialsHemofiltrationHumansKidneys, ArtificialPolystyrenesRenal DialysisUltrafiltrationJournal Article

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V A Davankov, L A Pavlova, M P Tsyurupa, D R Tur. 1997-02-07. Novel polymeric solid-phase extraction material for complex biological matrices. Portable and disposable artificial kidney.. https://doi.org/10.1016/s0378-4347(96)00307-6

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