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Biomedical subjects

L Arbus

Publications and source records attributed to L Arbus.

At least 37 records · Page 2Linked to original sources

[Somatotropin secretion during sleep in 60 cases of growth retardation in children].

A study of nocturnal somatotropic secretion with sleep polygraphic recording was performed in 60 children, aged 1 to 18 years and presenting with growth retardation greater than or equal to -2SD. GH secretion was analysed according to the peak value, the number of peaks greater than 5 ng/ml and the integrated concentration (surface under the curve divided by the duration of the test). The children were studied in four groups according to the responses to pharmacologic stimulation tests: a normal group (n = 7), a group with complete somatotropic deficiency (n = 4), a group with partial somatotropic deficiency (n = 39) and a group with dissociated responses (n = 12). Results are concordant between sleep secretion and pharmacologic tests in the first two groups. On the contrary, in the two last, the study of the sleep secretion allows to differentiate children with hyposecretion ("true partial deficiencies") from children with normal secretion ("false partial deficiencies") or abnormal responders). In other respects, correlations between LH maximum peak and stages of sleep are analysed. The maximum peak was observed in only 33.9% of cases during stage IV, 21.5% of cases during stages I, II, III, in 19.6% of cases during wakefulness and in 25% of cases during paradoxical stage. The maximum peak was observed in only 48% of cases during the first cycle of sleep and in 52% of cases during the other cycles. These results show that the correlation between maximum peak, stage IV and first cycle of sleep is not absolute.

Adolescent↗

[The role of paradoxical sleep in learning in man].

The authors have tried to specify the role of paradoxical sleep (PS) in the learning process in man. For their study they used 12 medical students. Three polygraphic recordings of sleep were performed over 3 consecutive days. The night of the third day was preceded by the learning test (a series of 4 tests). A simultaneous study was carried out of the effects of learning on sleep and vice versa. This study does not show any significant increase in the total time of paradoxical sleep during the night which followed the learning. Only the second period of PS was increased. Thus, this research does not seem to confirm the results obtained in animals. But this disagreement may be explained by the limited number of subjects or by the contents of the tests used. On the other hand, the authors did obtain results which seem to confirm the favourable influence of sleep as a whole on the learning process.

Adolescent↗

[Anterior and posterior medullary analgesic stimulation, using a percutaneous implantation technic].

The technique of percutaneous implantation of a pain-relieving stimulator reduces the surgical procedure considerably. This advantage is, however, lessened by the absence of precision in placing epidural electrodes, and by the risk of their later displacement leading to inadequate stimulation. To reduce this disadvantage the authors suggest a technique that is a modification of the classical open procedure: it is particularly suitable for implantation at the cervico-dorsal junction. In 12 patients treated by percutaneous implantation, 5 received, from epidural electrodes, an anterior medullary electrical stimulation which caused analgesia without paraesthesiae in the painful ares. The results, however, do not justify a conclusion that anterior medullary stimulation is better than posterior column stimulation.

Adult↗

[The measurement of sensory conduction in the median nerve and its diagnostic value in the carpal canal syndrome (author's transl)].

The authors studied the rate of sensory conduction of the median nerve in three groups of subjects: a group including subjects of different ages in order to determine the variations in conduction and the evoked response as a function of age; a group of patients with the carpal canal syndrome; a group treated by median nerve infiltration in the carpal canal. It was confirmed that there is a slowing of the rate of sensory conduction and spreading of the evoked response in the elderly subjects. The electromyographic data in the carpal canal syndrome is defined, as well as the difficulty of diagnosis which sometimes necessitates specific measurement of the conduction rate between the carpal canal limits.

Adolescent↗