Pathogenic concept of fat embolism. Clinical and biological study of 18 cases.
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Biomedical subjects
Publications and source records attributed to L Arbus.
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In 45 cases of ruptured intra-cranial aneurysms the authors studied the standard E.E.G. data under carotid compression and controlled hypotension; the changes observed were analysed and their value assessed for judging the state of the patient's cerebral circulation. A normal resting E.E.G. carries a good prognosis. Carotid compression and controlled hypotension provide a useful assessment of the supply and elasticity of the cerebral vessels; the occurrence of slow waves during controlled hypotension is an alarm signal which often helps in anaesthetic procedure.
Brain electrical activity mapping (BEAM) allows the study of electrical visual reactivity on a computerized electroencephalogram (EEG). We carried out 150 BEAM studies on 120 infants to evaluate the usefulness and reliability of this noninvasive technique in the assessment of vision in very young children, compared with other methods (clinical testing, preferential looking, and visual evoked potentials). BEAM demonstrated amblyopia at a cortical level and showed specific electrical signs of amblyopia. The visual reactivity was variably affected depending on the type of amblyopia present. In addition, different results of BEAM corresponded to different kinds of visual maturation delay and strabismus in the absence of amblyopia. BEAM appears to be useful in the initial screening and during treatment of deprivation and strabismic amblyopia, especially when other methods have failed to elicit the level of vision.
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Zopiclone 7.5 mg and triazolam 0.50 mg have been compared in a double-blind randomized cross-over sleep laboratory study. After a 6-day placebo, 12 healthy male volunteers aged 20-35 years received 2 active treatment sequences of 6 days separated by a 8-day placebo period and followed by a withdrawal period with placebo for 8 days. 22 polygraphic sleep recordings have been performed. The duration of nocturnal awakenings decreases at the beginning of treatment. Sleep onset latency is significantly decreased as well as the number of awakenings during sleep at the end of treatment. Both drugs improve the sleep efficiency index. Zopiclone increases total sleep time at the beginning and at the end of treatment. Triazolam increases this parameter at the end of the study only. Zopiclone, unlike triazolam increases the duration of deep NREM sleep-stages 3 and 4--at the beginning of treatment. No significant changes in sleep parameters were seen with zopiclone nor triazolam at the end of treatment. In sleep questionnaires, sleep onset latency is shorter under zopiclone than under triazolam and daytime drowsiness is less frequent with zopiclone.
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