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Biomedical subjects

L Ciompi

Publications and source records attributed to L Ciompi.

53 records · Page 3Linked to original sources

Late suicide in former mental patients.

Results from the long-term follow-up studies "The Enquĕte of Lausanne" are presented, concerning the incidence of suicide in old age of former mental patients. Among 1,891 studied deaths, 107 (5.6%) known suicides occurred; the suicide rate for all diagnostic groups, except mental retardation (only females), being considerably higher than in the general Swiss population of the same age, especially for depressions, alcoholism, neurotic and psychopathic personality disorders.

Adult↗

[Comparative study of long-term mortality in the mentally ill].

The mortality in mental illness has been studied after an average follow-up period of 3-4 decades in a material of 5661 former in-patients of the Psychiatric University Hospital of Lausanne (Switzerland), from which 3520 probands were dead at the date of reference. By use of an improved method, the calculations showed in all diagnostic groups, and generally more marked in women than in men, a 1,34 to 9,72 times higher mortality than in the general population, increasing in the following order: head injuries, psychogenic and psychopathic disorders, manic syndromes, schizophrenia, depressions, mental retardation, alcoholisme, other psychosis, epilepsy, general paralysis, other cerebro-organic conditions. Several possible explanations of these results are discussed.

Adjustment Disorders↗

Learning from outcome studies. Toward a comprehensive biological-psychosocial understanding of schizophrenia.

According to results from three major European long-term outcome studies on schizophrenia, from other comparable studies, and from additional investigations on rehabilitation and on the influence of psychosocial factors, long-term evolution of schizophrenia is much more variable and considerably better than hitherto admitted. On this basis, the author presents a comprehensive biological-psychosocial evolutionary model of schizophrenia in three phases, centered around the vulnerability- and information-processing hypotheses. Long-term evolution of schizophrenia cannot be sufficiently represented by a linear organic process mainly determined by genetic factors. Environmental and, in particular, psychosocial factors, also seem to play an important role. Vicious biological-psychosocial circles with multiple feedback effects can lead to non-linear escalating processes. Chronic states appear to be the result of complex interactions between preexisting vulnerability and autoprotective counterregulations on a biological, psychological and social level. Some therapeutic consequences and possible future developments of these concepts are presented.

Humans↗