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Biomedical subjects

L Clodius

Publications and source records attributed to L Clodius.

At least 37 records · Page 2Linked to original sources

[Place and value of tomodensitometry examination of malignant skin tumors of the face].

Computerized tomography of the face offers a new technique for the evaluation of malignant tumors. It serves to ascertain exactly the extension of the malignant process and to establish the indication for surgery in the best possible conditions. A brief clinical description of the most frequent tumors of the face is given and the indications for this examination are discussed. The technical aspect of CT is also presented. In the light of four cases selected among patients who had been treated for squamous cell carcinoma of the face, the authors demonstrate the value of the examination. They believe that computed tomography is fully indicated in recurrent tumors of the face and in complex localisation such as the medial angle of the eye, the external auditory canal, the alar base of the nose or the orbits.

Aged↗

[Plastic surgery therapy of extensive port-wine stain of the face].

In contrast to true hemangiomas which are vascular tumors, port-wine stains are vascular malformations consisting of mature teleangiectatic vessels in the dermis and the adjacent subcutis. In the case of large facial port-wine stains, no series of patients treated with consistently good results has so far been reported. The patients presented here have been treated by subtotal excision of the naevus flammeus and the resultant defects covered by carefully selected full thickness skin grafts. The results in 50 patients operated upon by this method, and the complications encountered are reported.

Adolescent↗

[Neuroradiology in the assessment and treatment of facial hemangiomas].

The introduction of superselective angiography of the branches of the external carotid artery has opened new perspectives in the evaluation and treatment of patients with craniofacial hemangioma. Angiographically craniofacial hemangiomas are classified into three morphologic (arteriovenous, capillary, venous) and two hemodynamic (high-flow and slow-flow) types. Embolization is a measure which serves for reduction of mass, significant decrease of intraoperative hemorrhage and treatment of skin complications such as necrosis, ulcerations, etc. Embolization should be followed by surgical resection of the hemangioma. This report is based on experience with angiographic exploration and embolization of 39 facial hemangiomas.

Adolescent↗

[Psychosocial problems and their management in patients with port-wine stain of the face].

Psychosocial problems and coping in 20 patients with facial naevus flammeus and their families are described. They can be divided into two groups, one of 15 patients in whom coping strategies are regressive, and one of 5 patients in whom they are progressive. In the regressive patients the self-esteem is unstable and social contacts are difficult. The progressive patients are hardly aware of negative reactions from their environment and are scarcely affected in their social contacts. The indication for treatment is discussed.

Adaptation, Psychological↗

[Scar revision].

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Cicatrix↗

The lymphatics of the groin flap.

This communication briefly discusses lymph-draining potentials and problems of skin flaps; describes specifically the lymphatics of the groin flap, an axial pattern flap; gives examples of its clinical application as a lymphatic wick; and explains its partial success and failure. The concept of axial pattern flaps was developed when the groin flap was described in 1972 by McGregor and Jackson. Attempts were subsequently made to delineate the extent of the vascular territories of these axial vessels. Although the flap was initially used as a pedicle flap, transfer of its vascular territory based on the axial vessels was soon undertaken, producing the so-called free flap. One desirable characteristic of this axial pattern flap was the remarkable absence of edema following elevation and transfer or transplantation to the new site. This stimulated one of us (L.C.) to review the lymph-draining potential of this flap.

Adult↗

[Problems of microsurgery in lymphedema].

Microsurgery for primary and secondary lymphedema at present consists of shunts between lymphatic vessels and veins. The surgical technique has been well established for more than a decade. The problems consist of the irreversible changes in the peripheral lymphatic system and in the connective tissues, as well as the obliteration of the deep lymphatics, best suited for lymphaticovenous anastomoses. These changes are recognized only late, after clinical swelling becomes manifest. Therefore, lymphaticovenous shunts should be performed prophylactically. Their number should be sufficiently high to solve the quantitative problem, caused by the reduced lymphatic transport capacity.

Extracellular Space↗

The problems of lymphatic microsurgery for lymphedema.

The problems of microsurgery for lymphedema consist of the discrepancy between the excellent technical possibilities, especially of microsurgical lympho-venous shunts and the subsequently insufficient reduction of the lymphedematous tissue fibrosis and sclerosis. Generally, the lymphatic surgeon considers the lymphatic system to be a canalicular system of drainage tubes, of lymph collectors. Bypassing a lymph block through peripheral lympho-venous shunts should therefore solve the problem of lymphstasis, present in each type of lymphedema. In chronic lymphedema however, not only the canalicular lymphatic system, but also the tissues, and integral part of the lymphatic system, are affected. In chronic lymphedema, canalicular repair, for reasons of quantitative lymph drainage, exceptionally only provides a "restitutio ad integrum" of the tissues, altered by lymph stasis.

Animals↗

Tissue changes in chronic experimental lymphoedema in dogs.

Chronic lymphoedema was experimentally induced in the legs of dogs and studied with the electron microscope, including by quantitation. It was found that some cells (macrophages, fibroblasts and, to a lesser extent, lymphocytes) increased greatly in numbers and relative volumes. Collagen (and fat cells) also greatly increased in relative volume. The lengths of blood vessels and initial lymphatics were much greater in the injured tissue. The numbers of small vesicles and vacuoles rose greatly in both types of vessels. Both also had many open endothelial junctions--although no doubt from different causes. It is probably caused by excessive accumulations of proteins, so chronic lymphoedema is probably a form of chronic inflammation.

Animals↗

[Bilateral amputation above the knee following incorrect treatment of lymphatic oedema (author's transl)].

A 31 years old man, suffering from lymphatic oedema of the left leg, underwent invasive diagnostics and subsequently a reduction plasty. This was followed by large leg ulcers and finally amputation above knee. Some months later, the right leg became also oedematous and was treated in the same way (invasive diagnostic, reduction-plasty, leg ulcers, amputation above knee). Shortly that the the right arm began to swell. Due to adequate conservative therapy the swelling of the right arm could be lessened.

Adult↗