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Biomedical subjects

L G Petersson

Publications and source records attributed to L G Petersson.

At least 55 records · Page 3Linked to original sources

Fluoride supplemented and non gamma 2 amalgam. A comparative clinical study into the primary and permanent dentition in children.

The purpose of the present study has been to test and compare the clinical performance of two dental analgams, a non gamma 2 amalgam (Amalcap) and a fluoride supplemented amalgam (Yata) containing 0,5% fluoride as stannous fluoride. During a period of almost one year, 196 fillings were made on contralateral cavities in primary as well as permanent teeth. The patients, all school children, received on the same occasion, randomly in one side of the mouth the F-supplemented amalgam and, in the corresponding contralateral tooth surface, the non gamma 2 amalgam. After four years of observation, no significant differences were found between the two tested amalgams concerning their clinical qualities such as corrosion, tooth colouration, filling edges, over- and underfilling, isthmus fractures or secondary caries. However, the low number of secondary caries occurring during the test period (2-3%) did not permit any conclusion about the preventive effect of the F-supplemented amalgam against secondary caries to be drawn. Further clinical studies, therefore, will show if fluoride supplemented amalgam is a really effective way to prevent secondary caries. Many categories of patients with extremely long intervals between dental treatments i e military and fleet personnel, certain foreign personnel, some handicapped groups and specific risk ages, as well as other specific intra-oral situations should benefit from filling therapy with fluoride supplemented amalgam. Such studies should be undertaken in order to evaluate the preventive clinical effect from fluoride supplemented amalgams.

Child↗

Effect on caries of different fluoride prophylactic programs in preschool children. A two year clinical study.

376 three-year old children were divided into four experimental groups and exposed to different combinations of preventive programs for a period of two years. All the groups were given the same basic prophylactic information. Additionally Group I received fluoride tablets (FLUDENT) for daily sucking twice a day plus a placebo dentifrice free of fluoride. Group II was given a fluoride dentifrice containing 0.025% F, (ACTA). Group III was given a placebo dentifrice plus fluoride varnish (Duraphat) twice a year. Group IV a fluoride dentifrice containing 0.025% F (ACTA) plus fluoride varnish (Duraphat) twice a year. No statistically significant difference in caries increment during the two experimental years was found between the groups. A tendency to lower caries increment was found in Group IV, i.e. in the children using the low fluoride dentifrice and treated twice a year with fluoride varnish.

Child, Preschool↗

Effects of premilking udder preparation on bacterial population, sediment, and iodine residue in milk.

Udder preparations that wet both udder surfaces and teats had the highest standard plate count in milk compared with methods that wet teats only. Physical action of cleaning teats with a dry towel lowered bacterial count compared with preparations wetting both udder surfaces and teats. Methods resulting in lowest bacterial counts were the use of water hose, wet towel, or premilking disinfectant teat dip followed by drying with paper towels. Counts of coliform and Staphylococcus sp. followed similar trends. In most comparisons, addition of udder wash sanitizer was of marginal or no benefit. Standard plate count of teat rinses after udder preparation confirmed the benefit of cleaning and drying teats. Physical manipulation of teats during cleaning was essential for lowering sediment in milk. Drying of teats with a paper towel for at least 10 s after dipping with a 1% iodophor disinfectant dip was essential for reducing iodine residue. Both premilking and postmilking disinfectant teat dipping with a 1% iodophor teat dip caused higher iodine residue in milk than premilking disinfectant dip with subsequent drying. A .5% iodophor teat dip contributed less iodine in milk than a 1% iodophor teat dip. Premilking udder preparation affects bacterial count, sediment, and iodine residue in milk.

Animals↗

Fluorine concentration in primary tooth enamel in 6-year-olds after 3 years of daily intake of fluoride-containing tablets (Fludent).

The purpose of this study was to determine the posteruptive uptake of fluorine in primary tooth enamel after daily consumption of a fluoride-containing sucking tablet for three years. The material consisted of 17 children, who had been advised to suck on 1 NaF tablet (Fludent, 0.25 mg F) daily at bedtime from 3 to 6 years of age (test group), and 17 children without tablet supply (control group). No other fluoride preparation was used during the period. A chemical biopsy method, described by Koch et al. (1982), was used to determine the fluorine concentration in enamel at the age of 6. Two consecutive layers on the upper central primary incisors of each child were etched off by perchloric acid. Chemical analysis of the test solutions was used to determine the thickness of the enamel layers and the fluorine content. Statistical evaluations were performed by analysis-of-variance. The results showed that fluorine was incorporated in primary tooth enamel as a topical effect of the fluoride tablet intake. There was a statistically significant difference (p less than 0.05) between the groups regarding fluorine measured on the layers combined and in the out layer (approximately equal to 5 micron thick), but not in the inner layer (approximately equal to 8 micron). It was concluded that the posteruptively increased enamel fluorine concentration probably contributes to the caries-preventive effect of NaF tablets.

Biopsy↗

Kinetics of fluorine in deciduous enamel after application of fluoride-containing varnish (Duraphat). II. A statistical approach to the design and evaluation of a clinical experiment.

The aim of this report is to discuss the design and technique for evaluation of an in vivo experiment on the kinetics of fluorine in deciduous enamel after application of fluorine-containing varnish (Duraphat). The analysis of variance technique used in the analysis of the results of the experiments is described in more detail than in the preceding report. The figure technique used in this report series is described. The method error study performed before carrying out the main experiment is analysed. A brief discussion follows about the consequences that different method errors have on the design of the experiment. The conclusion is that analysis of variance is a more reliable tool than multiple t-test, when evaluation of experiments is to be carried out.

Analysis of Variance↗

Kinetics of fluorine in deciduous enamel after application of fluoride-containing varnish (Duraphat).

The fluorine concentration in tooth enamel was determined in vivo after one single application of Duraphat fluoride varnish from 24 hours up to six months after treatment. A micro-acid-drop technique was used in 68 clinically intact deciduous upper central incisors in 34 pre-school children 4-5 years of age to determined the fluoride concentration in the enamel. The experimental data from the biopsy procedures were analysed by means of analysis of variance. The application of fluoride varnish results in an increase in fluoride in surface as well as subsurface enamel 24 hours after treatment. Thereafter a releasing process of fluorine from the enamel seems to start. Therefore the results indicate that there might be a caries inhibiting effect of fluoride varnish in primary enamel based more upon the kinetics of fluorine rather than a permanent uptake.

Child, Preschool↗

Inhibiting effect on demineralization of permanent root surfaces after different topical application of fluorides and a solution containing Fe- and Al-ions.

Fifteen roots were used in this study to compare different topical fluoride compounds on the inhibiting effect of artificial root surface carious lesions. A 2% NaF-solution, Duraphat and a test solution-containing Fe+3, Al+3 with and without fluoride were tested. The results indicated that only the test solution independent of fluoride was able to increase acid resistance. No differences could be observed between the controls and the surfaces treated with the other fluoride agents. The test solution thus seem to be applicable against root surface caries.

Administration, Topical↗

Effect of 250 and 1000 ppm fluoride dentifrice on caries. A three-year clinical study.

In a 3-year clinical trial, the caries prophylactic effect of two dentifrices containing 1000 ppm F and one containing 250 ppm F was compared. 541 twelve and thirteen-year-old children took part in the study. The children were randomly divided into three groups. Each group of children and their families used one of the dentifrices daily at home. The children were examined for caries at the start of the study and again after an interval of one year. The caries increment was equal in the three groups during the experimental period. This indicates that a 250 ppm F dentifrice has the same caries preventive effect as a 1000 ppm F dentifrice.

Adolescent↗

Development of artificial carious lesions in enamel after F-varnish (Duraphat) and F-Fe-Al-solution treatment.

An acidified gel system was used to study the development of initial enamel lesions using a test solution containing fluoride in combination with iron and aluminium ions compared to a fluoride varnish (Duraphat). The experiments were performed on both permanent and deciduous teeth. The results showed that the fluoride varnish was superior in retarding the development of initial enamel lesions compared to the test solution. The expected positive effect of trace elements in combination with fluorine could be demonstrated in this experiment. Deciduous enamel showed less acid resistance than permanent enamel under similar experimental conditions.

Aluminum↗

Effect of flouride varnish (Duraphat) treatment every six months compared with weekly mouthrinses with 0.2 per cent NaF solution on dental caries.

Recent studies have shown a high fluorine uptake in the enamel and a considerable caries reduction following the application of varnished containing fluoride. As the application is easy to carry out it may in certain situations serve as an alternative to other topical fluoride school programmes. The aim of the present study, therefore, was to compare the caries increment in schoolchildren exposed to a fluoride varnish (Duraphat) every six months and in children receiving the conventional weekly fluoride mouthrinsing programme with 0.2 per cent sodium fluoride over a two-year period. Two hundred 14-year-old children, divided into one test and one control group took part in the study. They were clinically and radiographically examined every year. Preexperimental data revealed no differences between the groups. During the experimental period the children in the fluoride varnish group developed a statistically significant lower number of new carious lesions compared with those in the mouthrinsing group. The difference in caries increment was about 30 per cent. Further clinical studies to compare the effects of various topical fluoride programmes are recommended.

Adolescent↗