PubMed Health⌕ Search

Biomedical subjects

L G Wiman

Publications and source records attributed to L G Wiman.

At least 55 records · Page 3Linked to original sources
PubMed1976

Scanning electron microscopy of the bronchial mucosa in some lung diseases using bronchoscopy specimens. A pilot study including cases of bronchial carcinoma, sarcoidosis, silicosis and tuberculosis.

In order to study the lung defence mechanisms and the mucociliary transport system scanning electron microscopy was performed on biopsy specimens obtained at bronchoscopy under local anaesthesia. There were great variations in the appearance of the cilitated epithelium from the large bronchi in 40 patients with bronchial carcinoma, sarcoidosis, silicosis, tuberculosis and other lung diseases. Areas with a low frequency of cilia were observed mainly in granulomatous disorders, and in silicosis, atypical cilia occurred abundantly. Squamous metaplasia with a complete loss of cilia was found in chronic bronchitis, bronchial carcinoma, after radiotherapy and in two of seven cases of sarcoidosis. Scanning electron microscopy seems to be an excellent method for studying the surface of the bronchial epithelium in many lung diseases, and may prove to be helpful in occupational medicine.

Adult↗
PubMed1975

Pulmonary lesions and autoimmune reactions after long-term nitrofurantoin treatment.

Hypersensitivity reactions in two women with pulmonary lesions, autoimmune reactions with positive antinuclear factor and liver damage following long-term nitrofurantoin treatment are discussed. One patient had taken nitrofurantoin for more than 1 year and the other for more than 2 when their symptoms appeared. They were in a very poor condition, but recovered when the drug was withdrawn. Lymphocyte transformation test in vitro showed significant blast-transformation, indicating the involvement of immunological mechanisms. Treatment with corticosteroids had not been instituted.

Autoimmune Diseases↗