Decreased deformability in aging erythrocytes.
Deformability of bovine erythrocytes separated according to density (and age) was estimated by a modified Teitel's filterability test, the centrifugational test of Sirs, and viscosity measurements of cell suspensions. Both youngest and oldest erythrocytes were found to be less deformable than middle-aged cells, a result speaking against any chief role for deformability in the recognition of senescent erythrocytes and their removal from the circulation.
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