[Changes in the blood sugar, serum insulin, cortisol and growth hormone levels in brain injuries].
Explore the source record for details and available documents.
Biomedical subjects
Publications and source records attributed to L Kammerer.
Explore the source record for details and available documents.
Dermatoglyphic features of 290 children and 180 adults with diabetes mellitus were investigated. WD occurred significantly more frequently on the fingers, and pattern intensity was low in certain interdigital areas in these patients. A high TRC value was more frequent in both girls and boys with diabetes mellitus than in the controls.
In patients with brain injury a correlation was found between the states of consciousness and the fasting (basal) blood-sugar level. Deep coma was associated with a high blood-sugar level, whereas when consciousness was regained a prompt decrease in the blood-sugar level was observed. It is concluded that brain lesions which affect the state of consciousness also influence the fasting glucose level. The degree and course of the blood-sugar changes may have prognostic significance.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
The left ventricular systolic function of 32 patients with insulin-dependent diabetes mellitus was investigated by measurement of systolic time intervals. Patients with clinical signs of sclerosis in the coronary arteries were excluded. Twenty-nine sex- and age-matched healthy people served as controls. Resting values of PEP/LVET ratio and of the corrected pre-ejection period were significantly higher in diabetics than in controls. The alterations of systolic time intervals during volume-loading induced by passive leg-raising as well as by isometric handgrip test indicated an increase in left ventricular performance in healthy people. The unchanged systolic time intervals observed in diabetics during the same loadings indicated a decrease in the functional reserve of the diabetic left ventricle. The systolic time intervals observed in patients with type-1 diabetes could be evaluated as a preclinical abnormality of left ventricular performance and as early signs of diabetic cardiomyopathy.
In vitro platelet aggregometry was performed in 201 patients with diabetes mellitus, and in 106 controls. The complication-free and retinopathic patients showed hyperaggregability to collagen and arachidonic acid, and also to epinephrine and adenosine diphosphate when neuropathy occurred. Patients with nephropathy, both with and without azotemia, had diminished in vitro platelet responses to each of the four stimuli as compared to age- and sex-matched controls. These characteristics were independent of the type of diabetes. It is concluded that diabetic nephropathy is characterized by reduced platelet in vitro reactivity. Further research is necessary to explain in vitro hypoaggregability in contrast to the numerous proofs of in vivo hyperfunction of platelets in diabetes.